Search database by RMgm ID
RMgm-214
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1315700; Gene model (P.falciparum): PF3D7_1452000; Gene product: rhoptry neck protein 2 (RON2) |
Phenotype | No phenotype has been described |
RMgm-215
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1418300; Gene model (P.falciparum): PF3D7_1320000; Gene product: golgi protein 1 | rhoptry protein 2, putative (PRP2, putative rhoptry protein 2) Name tag: EGFP |
Phenotype |
Asexual bloodstage;
Oocyst;
Sporozoite; |
RMgm-216
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1418300; Gene model (P.falciparum): PF3D7_1320000; Gene product: golgi protein 1 | rhoptry protein 2, putative (PRP2, putative rhoptry protein 2) |
Phenotype | No phenotype has been described |
RMgm-217
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0819900; Gene model (P.falciparum): PF3D7_0919000; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) Name tag: GFP |
Transgene |
Transgene Plasmodium: Gene model: PBANKA_0819900; Gene model (P.falciparum): PF3D7_0919000; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) Promoter: Gene model: PBANKA_0819900; Gene model (P.falciparum): PF3D7_0919000; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) 3'UTR: Gene model: PBANKA_0819900; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-or d-type unit)) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-218
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0819900; Gene model (P.falciparum): PF3D7_0919000; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) Name tag: GFP |
Transgene |
Transgene Plasmodium: Gene model: PBANKA_0819900; Gene model (P.falciparum): PF3D7_0919000; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) Promoter: Gene model: PBANKA_0819900; Gene model (P.falciparum): PF3D7_0919000; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) 3'UTR: Gene model: PBANKA_0819900; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-or d-type unit)) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-219
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0719900; Gene model (P.falciparum): PF3D7_0417800; Gene product: cdc2-related protein kinase 1 (CRK-1) |
Phenotype | No phenotype has been described |
RMgm-220
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0901300; Gene model (P.falciparum): PF3D7_1147800; Gene product: membrane associated erythrocyte binding-like protein (MAEBL) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-221
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PBANKA_0837161; Gene model (P.falciparum): Not available; Gene product: BIR protein PIR protein (BIR38, Plasmodium berghei interspersed repeat protein 38) Promoter: Gene model: PBANKA_0837161; Gene model (P.falciparum): Not available; Gene product: BIR protein PIR protein (BIR38, Plasmodium berghei interspersed repeat protein 38) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Asexual bloodstage;
|
RMgm-222
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0515000; Gene model (P.falciparum): PF3D7_1031000; Gene product: ookinete surface protein P25 (Pbs25; P25) Details mutation: P25 and P28 of P. berghei replaced by the P25 of P. vivax (PVP01_0616100) |
Mutated | Gene model (rodent): PBANKA_0514900; Gene model (P.falciparum): PF3D7_1030900; Gene product: ookinete surface protein P28 (Pbs21; P28) Details mutation: P25 and P28 of P. berghei replaced by the P25 of P. vivax (PVP01_0616100) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-223
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0515000; Gene model (P.falciparum): PF3D7_1031000; Gene product: ookinete surface protein P25 (Pbs25; P25) Details mutation: P25 and P28 of P. berghei replaced by a hybrid of PbP25 and P25 of P. vivax (PVP01_0616100) |
Mutated | Gene model (rodent): PBANKA_0514900; Gene model (P.falciparum): PF3D7_1030900; Gene product: ookinete surface protein P28 (Pbs21; P28) Details mutation: P25 and P28 of P. berghei replaced by a hybrid of PbP25 and P25 of P. vivax (PVP01_0616100) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-224
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1349100; Gene model (P.falciparum): PF3D7_1335100; Gene product: merozoite surface protein 7 (MSP7) |
Phenotype |
Asexual bloodstage;
|
RMgm-225
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1102200; Gene model (P.falciparum): PF3D7_0502400; Gene product: merozoite surface protein 8 | ring-stage membrane protein 1 (MSP8) Details mutation: The protein lacks the C-terminal EGF domains and the GPP-anchor sequence. |
Phenotype |
Asexual bloodstage;
|
RMgm-226
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: LacZ (β-Galactosidase) Promoter: Gene model: PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: PBANKA_0403200; Gene product: circumsporozoite (CS) protein (CSP) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-227
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PBANKA_0719300; Gene model (P.falciparum): PF3D7_0417200; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Asexual bloodstage;
Oocyst;
Sporozoite; Liver stage; |
RMgm-228
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0414800; Gene model (P.falciparum): PF3D7_0906500; Gene product: arginase |
Phenotype |
Asexual bloodstage;
|
RMgm-229
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0925500; Gene model (P.falciparum): PF3D7_1122800; Gene product: calcium-dependent protein kinase 6 (CDPK6) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-230
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1442000; Gene model (P.falciparum): PF3D7_1227200; Gene product: potassium channel (Kch1) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-231
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1432200; Gene model (P.falciparum): PF3D7_1216500; Gene product: male development gene 1 | protein of early gametocyte 3 (MDV-1; PEG3; MDV-1/PEG3) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-232
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1006200; Gene model (P.falciparum): PF3D7_0408600; Gene product: sporozoite invasion-associated protein 1 (Sporozoite Invasion-Associated Protein-1; SIAP-1; SIAP-1/ag17/S5) Name tag: mCherry |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-233
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1006200; Gene model (P.falciparum): PF3D7_0408600; Gene product: sporozoite invasion-associated protein 1 (Sporozoite Invasion-Associated Protein-1; SIAP-1; SIAP-1/ag17/S5) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-234
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1006200; Gene model (P.falciparum): PF3D7_0408600; Gene product: sporozoite invasion-associated protein 1 (Sporozoite Invasion-Associated Protein-1; SIAP-1; SIAP-1/ag17/S5) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_1006200; Gene product: sporozoite invasion-associated protein 1 (Sporozoite Invasion-Associated Protein-1; SIAP-1; SIAP-1/ag17/S5) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-235
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1037500; Gene model (P.falciparum): PF3D7_1411100; Gene product: conserved Plasmodium membrane protein, unknown function (Adenylyl cyclase α; ACα) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-236
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0417100; Gene model (P.falciparum): PF3D7_0904300; Gene product: conserved protein, unknown function (CRAGS, CRMP-related antigen of gametocytes and schizonts) |
Phenotype | No phenotype has been described |
RMgm-237
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1024600; Gene model (P.falciparum): PF3D7_1418100; Gene product: liver specific protein 1, putative (LISP1, liver specific protein 1) |
Phenotype |
Liver stage; |
RMgm-238
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0903600; Gene model (P.falciparum): PF3D7_1145400; Gene product: dynamin-like protein (DYN1; dynamin1) |
Phenotype | No phenotype has been described |
RMgm-239
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0912100; Gene model (P.falciparum): PF3D7_1136500; Gene product: casein kinase 1 |
Phenotype | No phenotype has been described |
RMgm-241
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1413100; Gene model (P.falciparum): PF3D7_1314600; Gene product: lipoate-protein ligase 1 (lipoic acid protein ligase A1) |
Phenotype | No phenotype has been described |
RMgm-242
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1364300; Gene model (P.falciparum): PF3D7_1351600; Gene product: glycerol kinase |
Phenotype | No phenotype has been described |
RMgm-243
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1204900; Gene model (P.falciparum): PF3D7_1006700; Gene product: conserved Plasmodium protein, unknown function |
Phenotype | No phenotype has been described |
RMgm-244
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0403800; Gene model (P.falciparum): PF3D7_0305300; Gene product: conserved Plasmodium membrane protein, unknown function |
Phenotype | No phenotype has been described |
RMgm-246
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0819900; Gene model (P.falciparum): PF3D7_0919000; Gene product: nucleosome assembly protein (NAPS, nucleosome assembly protein S; SET) |
Phenotype | No phenotype has been described |
RMgm-247
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1443000; Gene model (P.falciparum): PF3D7_1228300; Gene product: NIMA related kinase 1 (nek-1) |
Phenotype | No phenotype has been described |
RMgm-248
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0836300; Gene model (P.falciparum): PF3D7_0935800; Gene product: cytoadherence linked asexual protein 9 (CLAG9) |
Phenotype | No phenotype has been described |
RMgm-250
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1402600; Gene model (P.falciparum): PF3D7_1304100; Gene product: DNA ligase I (PfLig1) |
Phenotype | No phenotype has been described |
RMgm-251
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_1432200; Gene model (P.falciparum): PF3D7_1216500; Gene product: male development gene 1 | protein of early gametocyte 3 (MDV-1; PEG3; MDV-1/PEG3) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Gametocyte/Gamete;
|
RMgm-252
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1241700; Gene model (P.falciparum): PF3D7_0526900; Gene product: transmembrane emp24 domain-containing protein, putative |
Phenotype | No phenotype has been described |
RMgm-253
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0932200; Gene model (P.falciparum): PF3D7_1115600; Gene product: peptidyl-prolyl cis-trans isomerase |
Phenotype | No phenotype has been described |
RMgm-254
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1113400; Gene model (P.falciparum): PF3D7_0513700; Gene product: secreted ookinete protein, putative | 6-cysteine protein (PSOP12, putative secreted ookinete protein 12) |
Phenotype | No phenotype has been described |
RMgm-255
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1232200; Gene model (P.falciparum): PF3D7_0517400; Gene product: FACT complex subunit SPT16, putative (FACT-L; FACT) |
Phenotype | No phenotype has been described |
RMgm-256
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1229800; Gene model (P.falciparum): PF3D7_0615100; Gene product: enoyl-acyl carrier reductase (FABI) |
Phenotype | No phenotype has been described |
RMgm-257
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0616700; Gene model (P.falciparum): PF3D7_0719200; Gene product: NIMA related kinase 4 (serine/threonine protein kinase, Pfnek-4) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-259
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: GFP(gfp-mut3) fused to the HT-motif of the P. falciparum HRPII gene Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit)) |
Phenotype |
Asexual bloodstage;
|
RMgm-260
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1212700; Gene model (P.falciparum): PF3D7_1014300; Gene product: SPRY domain-containing protein, putative |
Phenotype | No phenotype has been described |
RMgm-261
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1231300; Gene model (P.falciparum): PF3D7_0516500; Gene product: major facilitator superfamily domain-containing protein, putative |
Phenotype | No phenotype has been described |
RMgm-262
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1018200; Gene model (P.falciparum): PF3D7_1426400; Gene product: MORN repeat protein, putative |
Phenotype | No phenotype has been described |
RMgm-263
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1463000; Gene model (P.falciparum): PF3D7_1250100; Gene product: osmiophilic body protein G377 (PbG377) |
Phenotype |
Gametocyte/Gamete;
|
RMgm-264
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0209300; Gene model (P.falciparum): PF3D7_0103800; Gene product: actin-related protein (ARP1; actin3) |
Phenotype | No phenotype has been described |
RMgm-265
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0915600; Gene model (P.falciparum): PF3D7_1132800; Gene product: aquaglyceroporin |
Phenotype |
Asexual bloodstage;
Sporozoite; Liver stage; |
RMgm-266
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0416700; Gene model (P.falciparum): PF3D7_0904700; Gene product: bacterial histone-like protein (PbHU) |
Phenotype | No phenotype has been described |
RMgm-267
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: GFP (with ACP leader sequence for apicoplast targeting) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR/TS) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit)) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-268
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Sporozoite; |
RMgm-269
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: Flp recombinase of yeast (Flp) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Insertion locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Sporozoite; |
RMgm-270
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0831000; Gene model (P.falciparum): PF3D7_0930300; Gene product: merozoite surface protein 1 (MSP-1, MSP1) Details mutation: The mutant contains a FRTed 3'UTR of the msp-1 locus Details conditional mutagenesis: The 3'UTR of msp1 is removed in the sporozoite stage by the Flp/FRT system. |
Transgene |
Transgene not Plasmodium: Flp recombinase of yeast (Flp) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Insertion locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-271
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: GFP (GFP-mut3) Promoter: Gene model: PBANKA_0304900; Gene model (P.falciparum): PF3D7_0207500; Gene product: serine repeat antigen 6 (PbSERA3) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Liver stage; |
RMgm-272
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0304900; Gene model (P.falciparum): PF3D7_0207500; Gene product: serine repeat antigen 6 (PbSERA3) Name tag: TAP |
Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-273
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0515000; Gene model (P.falciparum): PF3D7_1031000; Gene product: ookinete surface protein P25 (Pbs25; P25) Details mutation: P25 and P28 of P. berghei replaced by the P25 of P. falciparum (PF3D7_1031000) |
Mutated | Gene model (rodent): PBANKA_0514900; Gene model (P.falciparum): PF3D7_1030900; Gene product: ookinete surface protein P28 (Pbs21; P28) Details mutation: P25 and P28 of P. berghei replaced by the P25 of P. falciparum (PF3D7_1031000) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-274
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: GFP (mut3) Promoter: Gene model: PBANKA_0412900; Gene model (P.falciparum): PF3D7_0315200; Gene product: circumsporozoite- and TRAP-related protein 3'UTR: Gene model: PBANKA_0514900; Gene product: 28 kDa ookinete surface protein (Pbs21; P28) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (d-type unit)) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-275
Malaria parasite | P. yoelii |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PY17X_1337400; Gene model (P.falciparum): Not available; Gene product: duffy receptor, beta form precursor (erythrocyte binding like protein, EBL; PyEBL) |
Phenotype | No phenotype has been described |
RMgm-276
Malaria parasite | P. yoelii |
Genotype | |
Mutated | Gene model (rodent): PY17X_1337400; Gene model (P.falciparum): PF3D7_1301600; Gene product: duffy receptor, beta form precursor (erythrocyte binding like protein, EBL; PyEBL) Details mutation: The second Cys position in Region 6 of the ebl gene is substituted with Arg. |
Phenotype |
Asexual bloodstage;
|
RMgm-277
Malaria parasite | P. yoelii |
Genotype | |
Mutated | Gene model (rodent): PY17X_1337400; Gene model (P.falciparum): PF3D7_1301600; Gene product: erythrocyte binding antigen-140 (EBL; PyEBL) Details mutation: The Arg in Region 6 of the pyebl gene is substituted with Cys. |
Phenotype |
Asexual bloodstage;
|
RMgm-278
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites |
Phenotype |
Sporozoite; |
RMgm-279
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1024600; Gene model (P.falciparum): PF3D7_1418100; Gene product: liver specific protein 1, putative (LISP1, liver specific protein 1) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-280
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1024600; Gene model (P.falciparum): PF3D7_1418100; Gene product: liver specific protein 1, putative (LISP1, liver specific protein 1) |
Phenotype |
Liver stage; |
RMgm-281
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: ovalbumin (OVA) Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Insertion locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Asexual bloodstage;
|
RMgm-282
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1432200; Gene model (P.falciparum): PF3D7_1216500; Gene product: male development gene 1 | protein of early gametocyte 3 (MDV-1; PEG3; MDV-1/PEG3) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-283
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1432200; Gene model (P.falciparum): PF3D7_1216500; Gene product: male development gene 1 | protein of early gametocyte 3 (MDV-1; PEG3; MDV-1/PEG3) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-284
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1024600; Gene model (P.falciparum): PF3D7_1418100; Gene product: liver specific protein 1, putative (LISP1, liver specific protein 1) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-285
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: GFP fused to the amino terminal region of CSP (amino acids 1-74) with pexel motif mutations Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Asexual bloodstage;
|
RMgm-286
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: Mutation of two putative pexel/VTS motifs by mutation of conserved arginine and leucine to alanine |
Phenotype |
Liver stage; |
RMgm-288
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1240700; Gene model (P.falciparum): PF3D7_0525900; Gene product: NIMA related kinase 2 (NEK2) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-294
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1240700; Gene model (P.falciparum): PF3D7_0525900; Gene product: NIMA related kinase 2 (NEK2) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-295
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: tdTomato (RFP) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Asexual bloodstage;
Oocyst;
Sporozoite; Liver stage; |
RMgm-296
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: mCherry (RFP) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Asexual bloodstage;
Oocyst;
Sporozoite; Liver stage; |
RMgm-297
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1008500; Gene model (P.falciparum): PF3D7_1436300; Gene product: translocon component PTEX150 (PTEX150, Plasmodium translocon of exported proteins) |
Phenotype | No phenotype has been described |
RMgm-298
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1418900; Gene model (P.falciparum): PF3D7_1320600; Gene product: ras-related protein Rab-11A |
Phenotype | No phenotype has been described |
RMgm-299
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PBANKA_1418900; Gene model (P.falciparum): PF3D7_1320600; Gene product: ras-related protein Rab-11A Promoter: Gene model: PBANKA_1418900; Gene model (P.falciparum): PF3D7_1320600; Gene product: ras-related protein Rab-11A 3'UTR: Gene model: PBANKA_1418900; Gene product: ras-related protein Rab-11A Insertion locus: Gene model: PBANKA_1418900; Gene product: ras-related protein Rab-11A |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
|
RMgm-300
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0804300; Gene model (P.falciparum): PF3D7_0706700; Gene product: DNA mismatch repair protein MSH2, putative (MSH2-2) |
Phenotype | No phenotype has been described |
RMgm-301
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1318600; Gene model (P.falciparum): PF3D7_1454900; Gene product: conserved Plasmodium protein, unknown function |
Phenotype | No phenotype has been described |
RMgm-303
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1110900; Gene model (P.falciparum): PF3D7_0511400; Gene product: conserved Plasmodium protein, unknown function (J) |
Phenotype | No phenotype has been described |
RMgm-304
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0716400; Gene model (P.falciparum): PF3D7_0414400; Gene product: conserved Plasmodium protein, unknown function (L) |
Phenotype | No phenotype has been described |
RMgm-305
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1310300; Gene model (P.falciparum): PF3D7_1442600; Gene product: TRAP-like protein | sporozoite-specific transmembrane protein S6 (TREP; TRAP-related protein, S6; sporozoite specific gene 6; UOS3) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY04986; Gene product: TRAP-related protein (UOS3, up-regulated in ookinete sporozoites gene 3) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-306
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_1310300; Gene model (P.falciparum): PF3D7_1442600; Gene product: TRAP-like protein | sporozoite-specific transmembrane protein S6 (TREP; TRAP-related protein, S6; sporozoite specific gene 6; UOS3) Name tag: c-myc |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-307
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1136700; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCβ, guanylyl cyclase beta) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-308
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1333700; Gene model (P.falciparum): PF3D7_1470500; Gene product: phosphodiesterase delta, putative (PDEδ, phosphodiesterase delta) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-309
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1136700; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCβ, guanylyl cyclase beta) |
Disrupted | Gene model (rodent): PBANKA_1333700; Gene model (P.falciparum): PF3D7_1470500; Gene product: phosphodiesterase delta, putative (PDEδ, Phosphodiesterase delta) |
Phenotype |
Fertilization and ookinete;
|
RMgm-310
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0408200; Gene model (P.falciparum): PF3D7_0310100; Gene product: calcium-dependent protein kinase 3 (CDPK3) |
Disrupted | Gene model (rodent): PBANKA_1333700; Gene model (P.falciparum): PF3D7_1470500; Gene product: phosphodiesterase delta, putative (PDEδ, Phosphodiesterase delta) |
Phenotype |
Fertilization and ookinete;
|
RMgm-311
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: GFP |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-312
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1433700; Gene model (P.falciparum): PF3D7_1218100; Gene product: conserved Plasmodium protein, unknown function (H) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-313
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0508000; Gene model (P.falciparum): PF3D7_1023800; Gene product: conserved Plasmodium protein, unknown function (C) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-314
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1034400; Gene model (P.falciparum): PF3D7_1407800; Gene product: plasmepsin IV (PM4, plasmepsin 4) |
Phenotype |
Asexual bloodstage;
Oocyst;
Sporozoite; |
RMgm-315
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1034400; Gene model (P.falciparum): PF3D7_1407800; Gene product: plasmepsin IV (PM4, Plasmepsin 4) |
Phenotype |
Asexual bloodstage;
|
RMgm-316
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1034400; Gene model (P.falciparum): PF3D7_1407800; Gene product: plasmepsin IV (PM4, plasmepsin 4) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
|
RMgm-317
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-318
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1426200; Gene model (P.falciparum): PF3D7_0811300; Gene product: CCR4-associated factor 1 | poly(A) ribonuclease POP2 |
Phenotype | No phenotype has been described |
RMgm-321
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1038200; Gene model (P.falciparum): PF3D7_1403800; Gene product: nuclear formin-like protein MISFIT, putative | male-inherited sporulation factor important for transmission (MISFIT, male-inherited sporulation factor important for transmission) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-322
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1038200; Gene model (P.falciparum): PF3D7_1403800; Gene product: nuclear formin-like protein MISFIT, putative | male-inherited sporulation factor important for transmission (MISFIT, male-inherited sporulation factor important for transmission) Name tag: c-myc |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-323
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0910300; Gene model (P.falciparum): PF3D7_1138400; Gene product: guanylyl cyclase (Guanylyl cyclase alpha, GCα) |
Phenotype | No phenotype has been described |
RMgm-324
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0910300; Gene model (P.falciparum): PF3D7_1138400; Gene product: guanylyl cyclase (Guanylyl cyclase alpha, GCα) |
Phenotype | No phenotype has been described |
RMgm-325
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) |
Phenotype | No phenotype has been described |
RMgm-326
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0831000; Gene model (P.falciparum): PF3D7_0930300; Gene product: merozoite surface protein 1 (MSP-1; MSP1) |
Phenotype | No phenotype has been described |