Search database by RMgm ID
RMgm-328
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1232400; Gene model (P.falciparum): PF3D7_0517600; Gene product: F-actin-capping protein subunit beta, putative (CPβ, capping protein beta; UIS17, upregulated in infectious sporozoites gene 17) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-330
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0831000; Gene model (P.falciparum): PF3D7_0930300; Gene product: merozoite surface protein 1 (MSP-1, MSP1) Details mutation: Replacement of the P. berghei MSP-1 19 kD C-terminal with the P. falciparum MSP-1 19 kD C-terminal. |
Phenotype |
Asexual bloodstage;
|
RMgm-331
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-65) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene) |
Phenotype |
Asexual bloodstage;
Oocyst;
Liver stage; |
RMgm-332
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: CD4+ and CD8+ T cell epitopes and B cell epitopes (OVA, HA, gB) fused to GFP Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Asexual bloodstage;
|
RMgm-333
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-65) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit)) |
Phenotype |
Asexual bloodstage;
|
RMgm-334
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1040100; Gene model (P.falciparum): PF3D7_1401800; Gene product: choline kinase (CK) |
Phenotype | No phenotype has been described |
RMgm-335
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1415100; Gene model (P.falciparum): PF3D7_1316600; Gene product: choline-phosphate cytidylyltransferase (CCT) |
Phenotype | No phenotype has been described |
RMgm-336
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1127000; Gene model (P.falciparum): PF3D7_0628300; Gene product: choline/ethanolaminephosphotransferase, putative (CEPT) |
Phenotype | No phenotype has been described |
RMgm-337
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1360500; Gene model (P.falciparum): PF3D7_1347700; Gene product: ethanolamine-phosphate cytidylyltransferase (ECT) |
Phenotype | No phenotype has been described |
RMgm-338
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1040100; Gene model (P.falciparum): PF3D7_1401800; Gene product: choline kinase (CK) Name tag: GFP-mutant3 |
Phenotype |
Asexual bloodstage;
|
RMgm-339
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1415100; Gene model (P.falciparum): PF3D7_1316600; Gene product: choline-phosphate cytidylyltransferase (CCT) Name tag: GFP-mutant3 |
Phenotype |
Asexual bloodstage;
|
RMgm-340
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1127000; Gene model (P.falciparum): PF3D7_0628300; Gene product: choline/ethanolaminephosphotransferase, putative (CEPT) Name tag: GFP-mutant3 |
Phenotype |
Asexual bloodstage;
|
RMgm-341
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1360500; Gene model (P.falciparum): PF3D7_1347700; Gene product: ethanolamine-phosphate cytidylyltransferase (ECT) Name tag: GFP-mutant3 |
Phenotype |
Asexual bloodstage;
|
RMgm-342
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The endogenous P. berghei gene replaced with the ortholog of P. falciparum |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-344
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
|
RMgm-345
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1359600; Gene model (P.falciparum): PF3D7_1346700; Gene product: 6-cysteine protein | transmission blocking target antigen precursor (P48/45) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-346
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1359600; Gene model (P.falciparum): PF3D7_1346700; Gene product: 6-cysteine protein | transmission blocking target antigen precursor (P48/45) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-347
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1359700; Gene model (P.falciparum): PF3D7_1346800; Gene product: 6-cysteine protein (P47, Pfs47) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-348
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1359700; Gene model (P.falciparum): PF3D7_1346800; Gene product: 6-cysteine protein (P47; Pfs47) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-349
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1359700; Gene model (P.falciparum): PF3D7_1346800; Gene product: 6-cysteine protein (P47; Pfs47) |
Disrupted | Gene model (rodent): PBANKA_1359600; Gene model (P.falciparum): PF3D7_1346700; Gene product: 6-cysteine protein | transmission blocking target antigen precursor (P48/45) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-350
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0306100; Gene model (P.falciparum): PF3D7_0209000; Gene product: 6-cysteine protein | transmission-blocking target antigen s230 (P230) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-351
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0306000; Gene model (P.falciparum): PF3D7_0208900; Gene product: 6-cysteine protein (P230p) |
Phenotype | No phenotype has been described |
RMgm-352
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0306000; Gene model (P.falciparum): PF3D7_0208900; Gene product: 6-cysteine protein (P230p) |
Phenotype | No phenotype has been described |
RMgm-353
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1002100; Gene model (P.falciparum): PF3D7_0404400; Gene product: 6-cysteine protein (P36, Pbs36) |
Phenotype |
Liver stage; |
RMgm-354
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1107600; Gene model (P.falciparum): PF3D7_0508000; Gene product: 6-cysteine protein (P38, Pf38) |
Phenotype | No phenotype has been described |
RMgm-355
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1300700; Gene model (P.falciparum): PF3D7_1475500; Gene product: LCCL domain-containing protein (LAP2; LCCL/lectin adhesive-like protein 2; CCp1) Name tag: EGFP |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-356
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0204500; Gene model (P.falciparum): PF3D7_0109100; Gene product: LCCL domain-containing protein (LAP3; LCCL/lectin adhesive-like protein 2; CCp5) Name tag: EGFP |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-357
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details mutation: The mutant contains a mutated pkg gene with two FRT sites Details conditional mutagenesis: The FRTed sequenmce of pkg is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-358
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1301300; Gene model (P.falciparum): PF3D7_1474900; Gene product: trailer hitch homolog, putative (CITH; CAR-I/Trailer Hitch Homolog) Name tag: GFP |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-359
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1301300; Gene model (P.falciparum): PF3D7_1474900; Gene product: trailer hitch homolog, putative (CITH; CAR-I/Trailer Hitch Homolog) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-360
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1301300; Gene model (P.falciparum): PF3D7_1474900; Gene product: trailer hitch homolog, putative (CITH; CAR-I/Trailer Hitch Homolog) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-361
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1217700; Gene model (P.falciparum): PF3D7_0320800; Gene product: ATP-dependent RNA helicase DDX6 (DOZI, protein development of zygote inhibited) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-363
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1218100; Gene model (P.falciparum): PF3D7_0320400; Gene product: oocyst capsule protein Cap380, putative (PbCap380, Plasmodium oocyst capsule protein) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-365
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0305100; Gene model (P.falciparum): Not available; Gene product: serine repeat antigen 1 (SERA-1) Name tag: mCherry |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (230p) |
Phenotype |
Liver stage; |
RMgm-366
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0305000; Gene model (P.falciparum): Not available; Gene product: serine repeat antigen 2 (SERA-2) Name tag: mCherry |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-367
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0305100; Gene model (P.falciparum): Not available; Gene product: serine repeat antigen 1 (SERA1) |
Phenotype | No phenotype has been described |
RMgm-368
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0305000; Gene model (P.falciparum): Not available; Gene product: serine repeat antigen 2 (SERA2) |
Phenotype | No phenotype has been described |
RMgm-369
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0305100; Gene model (P.falciparum): Not available; Gene product: serine repeat antigen 1 (SERA1) |
Disrupted | Gene model (rodent): PBANKA_0305000; Gene model (P.falciparum): Not available; Gene product: serine repeat antigen 2 (SERA2) |
Phenotype | No phenotype has been described |
RMgm-370
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1210000; Gene model (P.falciparum): PF3D7_1008600; Gene product: zinc finger (CCCH type) protein, putative (S1) |
Transgene |
Transgene not Plasmodium: DsRed Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PY05712; Gene product: Zinc finger C-x8-C-x5-C-x3-H type, putative (S1) |
Phenotype | No phenotype has been described |
RMgm-371
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_0925800; Gene model (P.falciparum): PF3D7_1124500; Gene product: pyruvate dehydrogenase E1 component subunit alpha (PDH E1α) Name tag: c-myc |
Phenotype |
Sporozoite; Liver stage; |
RMgm-372
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_0715100; Gene model (P.falciparum): PF3D7_0815900; Gene product: dihydrolipoyl dehydrogenase, apicoplast (dihydrolipoamide dehydrogenase; PDH E3; E3) Name tag: c-myc |
Phenotype |
Sporozoite; Liver stage; |
RMgm-373
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1210000; Gene model (P.falciparum): PF3D7_1008600; Gene product: zinc finger (CCCH type) protein, putative (S1) |
Transgene |
Transgene not Plasmodium: DsRed Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PY05712; Gene product: Zinc finger C-x8-C-x5-C-x3-H type, putative (S1) |
Phenotype | No phenotype has been described |
RMgm-374
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1206800; Gene model (P.falciparum): PF3D7_1008600; Gene product: zinc finger (CCCH type) protein, putative (S1) |
Transgene |
Transgene not Plasmodium: DsRed Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger C-x8-C-x5-C-x3-H type, putative (S1) |
Phenotype | No phenotype has been described |
RMgm-375
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit)) |
Phenotype |
Asexual bloodstage;
|
RMgm-376
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_0925800; Gene model (P.falciparum): PF3D7_1124500; Gene product: pyruvate dehydrogenase E1 component subunit alpha (PDH E1α) |
Phenotype |
Liver stage; |
RMgm-377
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_0715100; Gene model (P.falciparum): PF3D7_0815900; Gene product: dihydrolipoyl dehydrogenase, apicoplast (dihydrolipoamide dehydrogenase; PDH E3; E3) |
Phenotype |
Liver stage; |
RMgm-378
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_0925800; Gene model (P.falciparum): PF3D7_1124500; Gene product: pyruvate dehydrogenase E1 component subunit alpha (PDH E1α) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PY00819; Gene product: pyruvate dehydrogenase E1 alpha subunit (PDH E1α) |
Phenotype |
Liver stage; |
RMgm-379
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_0715100; Gene model (P.falciparum): PF3D7_0815900; Gene product: dihydrolipoyl dehydrogenase, apicoplast (dihydrolipoamide dehydrogenase; PDH E3; E3) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PY00573; Gene product: lipoamide dehydrogenase (dihydrolipoamide dehydrogenase; PDH E3; E3) |
Phenotype |
Liver stage; |
RMgm-380
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
|
RMgm-381
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1114900; Gene model (P.falciparum): PF3D7_0515300; Gene product: phosphatidylinositol 3-kinase (PI3K) |
Phenotype | No phenotype has been described |
RMgm-382
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1017100; Gene model (P.falciparum): PF3D7_1427500; Gene product: DNA mismatch repair protein MSH2, putative |
Phenotype | No phenotype has been described |
RMgm-383
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1105100; Gene model (P.falciparum): PF3D7_0505500; Gene product: DNA mismatch repair protein MSH6, putative |
Phenotype | No phenotype has been described |
RMgm-384
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0930200; Gene model (P.falciparum): PF3D7_1117800; Gene product: DNA mismatch repair protein MLH |
Phenotype | No phenotype has been described |
RMgm-385
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0208000; Gene model (P.falciparum): PF3D7_0105300; Gene product: cyclase-associated protein (C-CAP, C-terminal actin binding domain) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-386
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0208000; Gene model (P.falciparum): PF3D7_0105300; Gene product: cyclase-associated protein (PbC-CAP; C-terminal actin binding domain) Details mutation: Replacement of the P. berghei c-cap gene with the c-cap ortholog of Cryptosporidium parvum. |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-387
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1360100; Gene model (P.falciparum): PF3D7_1347200; Gene product: nucleoside transporter 1 (NT1) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Oocyst;
Sporozoite; |
RMgm-388
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1103100; Gene model (P.falciparum): PF3D7_0503400; Gene product: actin-depolymerizing factor 1 (ADF1) |
Phenotype | No phenotype has been described |
RMgm-389
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0833000; Gene model (P.falciparum): PF3D7_0932200; Gene product: profilin (Pfn) |
Phenotype | No phenotype has been described |
RMgm-390
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0302500; Gene model (P.falciparum): PF3D7_0204700; Gene product: hexose transporter (hexose transporter 1; PfHT1, PfHT, PbHT) |
Phenotype | No phenotype has been described |
RMgm-391
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0302500; Gene model (P.falciparum): PF3D7_0204700; Gene product: hexose transporter (hexose transporter 1; PfHT1, PfHT, PbHT) Name tag: GFP |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-392
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0409400; Gene model (P.falciparum): PF3D7_0311400; Gene product: protein kinase, putative (putative kinase related protein; PKRP) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-393
Malaria parasite | P. yoelii |
Genotype | |
Mutated | Gene model (rodent): PY17X_0502200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 | protein of early gametocyte 4 (UIS4, up-regulated in infective sporozoites, ETRAMP10.3) Details mutation: Replacement of P. yoelii uis4 with P. falciparum PF10_0164, C-terminally myc-tagged |
Phenotype |
Sporozoite; Liver stage; |
RMgm-394
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Tagged | Gene model (rodent): PBANKA_0708100; Gene model (P.falciparum): PF3D7_0822500; Gene product: dynein light chain 1 | leucine-rich repeat protein (PbDLC1; DLC1; PfLRR7) Name tag: c-myc |
Phenotype | No phenotype has been described |
RMgm-395
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_0502200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 | protein of early gametocyte 4 (UIS4, up-regulated in infective sporozoites, ETRAMP10.3) Name tag: c-myc |
Phenotype | No phenotype has been described |
RMgm-396
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PBANKA_0813000; Gene model (P.falciparum): PF3D7_0911900; Gene product: falstatin | inhibitor of cysteine proteases (inhibitor of cysteine proteases; ICP) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr-ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-398
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1329800; Gene model (P.falciparum): PF3D7_1466400; Gene product: AP2 domain transcription factor AP2-SP (Apetala2; AP2-Sp, AP2 in sporozoites; ApiAP2) Name tag: GFP |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-399
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1329800; Gene model (P.falciparum): PF3D7_1466400; Gene product: AP2 domain transcription factor AP2-SP (Apetala2; AP2-Sp; AP2 in sporozoites; ApiAP2) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-400
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0905900; Gene model (P.falciparum): PF3D7_1143100; Gene product: AP2 domain transcription factor AP2-O, putative (AP2-O, AP2 in ookinetes; ApiAP2) Details mutation: The AP2 domain of AP2-O swapped with that of AP2-Sp (PBANKA_132980) |
Phenotype |
Fertilization and ookinete;
|
RMgm-401
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1137500; Gene model (P.falciparum): PF3D7_1361400; Gene product: actin-depolymerizing factor 2 (ADF2, actin-depolymerization factor 2) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-402
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1318000; Gene model (P.falciparum): PF3D7_1454300; Gene product: SNF1-related serine/threonine protein kinase KIN Details modification: Transposase mediated piggyBac insertion into the ORF |
Phenotype | No phenotype has been described |
RMgm-403
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1023400; Gene model (P.falciparum): PF3D7_1419800; Gene product: glutathione reductase (GR) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-404
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1023400; Gene model (P.falciparum): PF3D7_1419800; Gene product: glutathione reductase (GR) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-405
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1468100; Gene model (P.falciparum): Not available; Gene product: rhoptry protein (235EBP-1; Py235EBP-1; erythrocyte binding protein 1) |
Phenotype | No phenotype has been described |
RMgm-406
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: PiggyBac transposase Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit)) |
Phenotype |
Asexual bloodstage;
|
RMgm-407
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: PH domain of human phospholipase Cδ1 (hPLCδ1) fused to YFP and CFP Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Gametocyte/Gamete;
|
RMgm-408
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1434000; Gene model (P.falciparum): PF3D7_1218400; Gene product: triose or hexose phosphate/phosphate translocator, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-409
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1038000; Gene model (P.falciparum): PF3D7_1404100; Gene product: cytochrome c, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-410
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1035100; Gene model (P.falciparum): PF3D7_1407100; Gene product: rRNA 2'-O-methyltransferase fibrillarin, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-411
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0210300; Gene model (P.falciparum): PF3D7_0102800; Gene product: conserved Plasmodium protein, unknown function Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-412
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0815500; Gene model (P.falciparum): PF3D7_0914500; Gene product: conserved Plasmodium protein, unknown function Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-413
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0927900; Gene model (P.falciparum): PF3D7_1120300; Gene product: CorA-like Mg2+ transporter protein, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-414
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0907100; Gene model (P.falciparum): PF3D7_1141900; Gene product: inner membrane complex protein 1b, putative (inner membrane complex protein 1b, putative) Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-415
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1204600; Gene model (P.falciparum): PF3D7_1006400; Gene product: conserved Plasmodium protein, unknown function Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-416
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1119600; Gene model (P.falciparum): PF3D7_0620400; Gene product: merozoite surface protein 10 Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-417
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0824400; Gene model (P.falciparum): PF3D7_0923500; Gene product: cyclin-dependent kinases regulatory subunit, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-418
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0622300; Gene model (P.falciparum): PF3D7_0724800; Gene product: kelch domain-containing protein, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-419
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1436500; Gene model (P.falciparum): PF3D7_1221300; Gene product: conserved Plasmodium protein, unknown function Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-420
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1438400; Gene model (P.falciparum): PF3D7_1223500; Gene product: conserved Plasmodium protein, unknown function Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-421
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1326700; Gene model (P.falciparum): PF3D7_1463100; Gene product: conserved Plasmodium protein, unknown function, pseudogene Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-422
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0622400; Gene model (P.falciparum): PF3D7_0724900; Gene product: kinesin-19, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-423
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0913000; Gene model (P.falciparum): PF3D7_1135600; Gene product: condensin-2 complex subunit D3, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-424
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1208600; Gene model (P.falciparum): PF3D7_1010200; Gene product: DNA2/NAM7 helicase, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-425
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0936500; Gene model (P.falciparum): PF3D7_1111100; Gene product: replication factor C subunit 5, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-426
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0617900; Gene model (P.falciparum): PF3D7_0720400; Gene product: ferrodoxin reductase-like protein Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-427
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-428
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1225100; Gene model (P.falciparum): PF3D7_0805500; Gene product: conserved Plasmodium protein, unknown function Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-429
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0912000; Gene model (P.falciparum): PF3D7_1136600; Gene product: conserved Plasmodium protein, unknown function Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-430
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0708500; Gene model (P.falciparum): PF3D7_0822200; Gene product: phosphorylated CTD interacting factor 1 WW domain-containing protein, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-431
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1462400; Gene model (P.falciparum): PF3D7_1249500; Gene product: protein CutA, putative Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |
RMgm-432
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_1321100; Gene model (P.falciparum): PF3D7_1457400; Gene product: conserved Plasmodium protein, unknown function Details modification: Transposase mediated piggyBac insertion into ORF |
Phenotype | No phenotype has been described |