RMgmDB - Rodent Malaria genetically modified Parasites

RMgm-4958

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PbANKA_0800600; Gene model (P.falciparum): PF3D7_0702900; Gene product: centrin, putative
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-4959

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0209200; Gene model (P.falciparum): PF3D7_0103900; Gene product: parasite-infected erythrocyte surface protein (PIESP15)
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-4960

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0522500; Gene model (P.falciparum): PF3D7_0422100; Gene product: transmembrane emp24 domain-containing protein, putative
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Liver stage;

RMgm-4961

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1241700; Gene model (P.falciparum): PF3D7_0526900; Gene product: transmembrane emp24 domain-containing protein, putative
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Liver stage;

RMgm-4962

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0715500; Gene model (P.falciparum): PF3D7_0413500; Gene product: phosphoglucomutase-2 (PGM2) Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_0715500; Gene product: phosphoglucomutase-2 (PGM2)
Phenotype	Asexual bloodstage;

RMgm-4963

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1024800; Gene model (P.falciparum): PF3D7_1417900; Gene product: ATP synthase-associated protein, putative Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_1024800; Gene product: ATP synthase-associated protein, putative
Phenotype	Asexual bloodstage;

RMgm-4964

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0109600; Gene model (P.falciparum): PF3D7_0611300; Gene product: ATP synthase-associated protein, putative Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_0109600; Gene product: ATP synthase-associated protein, putative
Phenotype	Asexual bloodstage;

RMgm-4965

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0708900; Gene model (P.falciparum): PF3D7_0821900; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_0708900; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4966

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0310100; Gene model (P.falciparum): PF3D7_0213200; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_0310100; Gene product: PF3D7_0213200 (conserved protein, unknown function)
Phenotype	Asexual bloodstage;

RMgm-4967

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1203200; Gene model (P.falciparum): PF3D7_1004900; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_1203200; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4968

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0827900; Gene model (P.falciparum): PF3D7_0927100; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_0827900; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4969

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1103500; Gene model (P.falciparum): PF3D7_0503900; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_1103500; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4970

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0914000; Gene model (P.falciparum): PF3D7_1134400; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_0914000; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4971

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1350000; Gene model (P.falciparum): PF3D7_1336100; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_1350000; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4972

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1459800; Gene model (P.falciparum): PF3D7_1246700; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_1459800; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4973

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0814400; Gene model (P.falciparum): PF3D7_0913400; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_0814400; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4974

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0927100; Gene model (P.falciparum): PF3D7_1121200; Gene product: conserved protein, unknown function Name tag: triple-HA
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0914400; Gene model (P.falciparum): PF3D7_0831700; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) 3'UTR: Gene model: PBANKA_0914400; Gene product: heat shock protein 70 (HSP70x, HSP70-3, UIS24) Insertion locus: Gene model: PBANKA_0927100; Gene product: conserved protein, unknown function
Phenotype	Asexual bloodstage;

RMgm-4975

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0604400; Gene model (P.falciparum): PF3D7_1205700; Gene product: targeted glyoxalase II (tGLO2)
Phenotype	No phenotype has been described

RMgm-4976

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1004000; Gene model (P.falciparum): PF3D7_0406400; Gene product: cytosolic glyoxalase II (cGLO2)
Phenotype	No phenotype has been described

RMgm-4977

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0604400; Gene model (P.falciparum): PF3D7_1205700; Gene product: targeted glyoxalase II (tGLO2)
Disrupted	Gene model (rodent): PBANKA_1004000; Gene model (P.falciparum): PF3D7_0406400; Gene product: cytosolic glyoxalase II (cGLO2)
Phenotype	Liver stage;

RMgm-4978

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_1017000; Gene model (P.falciparum): PF3D7_1429200; Gene product: AP2 domain transcription factor AP2-O3, putative (ApiAP2; AP2-O3; PbAP2-FG2) Name tag: HA
Phenotype	Gametocyte/Gamete; Oocyst;

RMgm-4979

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_1017000; Gene model (P.falciparum): PF3D7_1429200; Gene product: AP2 domain transcription factor AP2-O3, putative (ApiAP2; AP2-O3; PbAP2-FG2)
Phenotype	Fertilization and ookinete;

RMgm-4980

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_0408600; Gene model (P.falciparum): PF3D7_0308000; Gene product: DNA polymerase delta small subunit, putative (dpod2) Name tag: GFP
Tagged	Gene model (rodent): PY17X_1323300; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (CCp2, LAP4) Name tag: mCherry
Phenotype	Gametocyte/Gamete;

RMgm-4981

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_0502300; Gene model (P.falciparum): PF3D7_1017000; Gene product: DNA polymerase delta catalytic subunit (dpod1) Name tag: GFP
Tagged	Gene model (rodent): PY17X_1323300; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (CCp2, LAP4) Name tag: mCherry
Phenotype	Gametocyte/Gamete;

RMgm-4982

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_0419400; Gene model (P.falciparum): PF3D7_0904800; Gene product: replication protein A1, small fragment (rpa1) Name tag: GFP
Tagged	Gene model (rodent): PY17X_1323300; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (CCp2, LAP4) Name tag: mCherry
Phenotype	Gametocyte/Gamete;

RMgm-4983

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_0805800; Gene model (P.falciparum): PF3D7_0705400; Gene product: DNA replication licensing factor MCM7 (mcm7) Name tag: GFP
Tagged	Gene model (rodent): PY17X_1323300; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (CCp2, LAP4) Name tag: mCherry
Phenotype	Gametocyte/Gamete;

RMgm-4984

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1347400; Gene model (P.falciparum): PF3D7_1332600; Gene product: DNA-(apurinic or apyrimidinic site) lyase 1 (APN1)
Phenotype	No phenotype has been described

RMgm-4985

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1347400; Gene model (P.falciparum): PF3D7_1332600; Gene product: DNA-(apurinic or apyrimidinic site) lyase 1 (APN1) Name tag: 3xHA-mCherry
Phenotype	Asexual bloodstage; Oocyst;

RMgm-4986

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0404100; Gene model (P.falciparum): PF3D7_0305600; Gene product: DNA-(apurinic or apyrimidinic site) endonuclease (APE1)
Phenotype	Liver stage;

RMgm-4987

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. berghei csp gene replaced by P. falciparum csp
Mutated	Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein \| sporozoite surface protein 2 (TRAP; SSP2) Details mutation: The P. berghei trap gene replaced by P. falciparum trap
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-4988

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1400800; Gene model (P.falciparum): PF3D7_1302200; Gene product: protein UIS3 (UIS3; ETRAMP13)
Transgene	Transgene not Plasmodium: Venus and luciferase (Veluc) Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_1400800; Gene product: protein UIS3 (UIS3)
Phenotype	Liver stage;

RMgm-4989

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1355700; Gene model (P.falciparum): PF3D7_1342600; Gene product: myosin A (MyoA) Details mutation: serine position 19 replaced with phosphorylation incompatible alanine
Phenotype	Sporozoite; Liver stage;

RMgm-4990

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: SYIPSAEKI amino acids replaced by SIINFEKL (H-2-Kb-restricted CD8+ T-cell epitope of ovalbumin)
Phenotype	No phenotype has been described

RMgm-4991

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0501200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 \| protein of early gametocyte 4 (UIS4; ETRAMP10.3) Details mutation: UIS4 tagged with amino acids SIINFEKL (a H-2-Kb-restricted CD8+ T-cell epitope of ovalbumin)
Phenotype	No phenotype has been described

RMgm-4992

Malaria parasite	P. yoelii
Genotype
Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) 3'UTR: Gene model: PBANKA_0403200; Gene product: circumsporozoite (CS) protein (CSP) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p; 230p)
Phenotype	Sporozoite;

RMgm-4993

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1446100; Gene model (P.falciparum): Pf3D7_ 1231400; Gene product: membrane protein ICM1 (ICM1) Name tag: triple-HA
Phenotype	Asexual bloodstage; Gametocyte/Gamete;

RMgm-4994

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PBANKA_1446100; Gene model (P.falciparum): Pf3D7_ 1231400; Gene product: membrane protein ICM1 (ICM1)
Phenotype	No phenotype has been described

RMgm-4995

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1446100; Gene model (P.falciparum): Pf3D7_ 1231400; Gene product: membrane protein ICM1 (ICM1) Details mutation: 'promoter swap mutant': the promoter of icm1 replaced with the ama1 promoter (PBANKA_0915000).
Phenotype	Gametocyte/Gamete;

RMgm-4996

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1446100; Gene model (P.falciparum): Pf3D7_ 1231400; Gene product: membrane protein ICM1 (ICM1) Details mutation: 'promoter swap mutant': the promoter of icm1 replaced with the clag9 promoter (PBANKA_140060).
Phenotype	Gametocyte/Gamete;

RMgm-4997

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0201700; Gene model (P.falciparum): PF3D7_0112100; Gene product: PIMMS1 protein (PIMMS1)
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Oocyst; Sporozoite; Liver stage;

RMgm-4998

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1457700; Gene model (P.falciparum): PF3D7_1244500; Gene product: PIMMS57 protein (PIMMS57)
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Oocyst; Sporozoite; Liver stage;

RMgm-4999

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1422900; Gene model (P.falciparum): PF3D7_0814600; Gene product: PIMMS22 protein, putative (PIMMS22)
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Oocyst; Sporozoite; Liver stage;

RMgm-5000

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0201700; Gene model (P.falciparum): PF3D7_0112100; Gene product: PIMMS1 protein (PIMMS1) Name tag: GFP
Phenotype	Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5001

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1457700; Gene model (P.falciparum): PF3D7_1244500; Gene product: PIMMS57 protein (PIMMS57) Name tag: GFP
Phenotype	Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5002

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1422900; Gene model (P.falciparum): PF3D7_0814600; Gene product: PIMMS22 protein, putative (PIMMS22) Name tag: GFP
Phenotype	Fertilization and ookinete; Sporozoite;

RMgm-5003

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1028300; Gene model (P.falciparum): PF3D7_1414400; Gene product: serine/threonine protein phosphatase PP1 (PP1) Details mutation: 'promoter swap mutant': the promoter of pp1 replaced with the ama1 promoter (PBANKA_0915000).
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

RMgm-5004

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1028300; Gene model (P.falciparum): PF3D7_1414400; Gene product: serine/threonine protein phosphatase PP1 (PP1) Name tag: GFP
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

RMgm-5005

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: Deletion of (N-terminal) repeats of the central repeat sequence of CSP
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-5006

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: Deletion of (C-terminal) repeats of the central repeat sequence of CSP
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-5007

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: Deletion of of internally located repeats of the central repeat sequence of CSP
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Sporozoite; Liver stage;

RMgm-5008

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: randomly scrambled amino acid sequences of the repeats of the central repeat sequence of CSP
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Sporozoite; Liver stage;

RMgm-5009

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0202700; Gene model (P.falciparum): PF3D7_0111000; Gene product: kinesin-8B, putative
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

RMgm-5010

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PBANKA_1458300; Gene model (P.falciparum): PF3D7_1245100; Gene product: kinesin-13, putative (KLP8)
Phenotype	No phenotype has been described

RMgm-5011

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1458800; Gene model (P.falciparum): PF3D7_1245600; Gene product: kinesin-15, putative
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

RMgm-5012

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0622400; Gene model (P.falciparum): PF3D7_0724900; Gene product: kinesin-20, putative
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

RMgm-5013

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0805900; Gene model (P.falciparum): PF3D7_0319400; Gene product: kinesin-8X
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Oocyst; Sporozoite;

RMgm-5014

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0807700; Gene model (P.falciparum): PF3D7_0317500; Gene product: kinesin-5 (EG5)
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Sporozoite; Liver stage;

RMgm-5015

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1208200; Gene model (P.falciparum): Not available; Gene product: kinesin-4
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-5016

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_060950; Gene model (P.falciparum): PF3D7_1211000; Gene product: kinesin-X3, putative (X3)
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-5017

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0902400; Gene model (P.falciparum): PF3D7_1146700; Gene product: kinesin-X4, putative (X4)
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-5018

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1458300; Gene model (P.falciparum): PF3D7_1245100; Gene product: kinesin-13, putative (KLP8) Details mutation: 'promoter swap mutant': the promoter of kinesin-1 replaced with the clag9 promoter (PBANKA_0836300).
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5019

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0202700; Gene model (P.falciparum): PF3D7_0111000; Gene product: kinesin-8B, putative Name tag: GFP
Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

RMgm-5020

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1458300; Gene model (P.falciparum): PF3D7_1245100; Gene product: kinesin-13, putative (KLP8) Name tag: GFP
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

RMgm-5021

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1458800; Gene model (P.falciparum): PF3D7_1245600; Gene product: kinesin-15, putative Name tag: GFP
Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

RMgm-5022

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0622400; Gene model (P.falciparum): PF3D7_0724900; Gene product: kinesin-20, putative Name tag: GFP
Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5023

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0805900; Gene model (P.falciparum): PF3D7_0319400; Gene product: kinesin-8X Name tag: GFP
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5024

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0807700; Gene model (P.falciparum): PF3D7_0317500; Gene product: kinesin-5 (EG5) Name tag: GFP
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5025

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_060950; Gene model (P.falciparum): PF3D7_1211000; Gene product: kinesin-X3, putative (X3) Name tag: GFP
Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5026

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0902400; Gene model (P.falciparum): PF3D7_1146700; Gene product: kinesin-X4, putative (X4) Name tag: GFP
Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

RMgm-5027

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1208200; Gene model (P.falciparum): Not available; Gene product: kinesin-4, putative Name tag: GFP
Phenotype	Oocyst;

RMgm-5029

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1437500; Gene model (P.falciparum): PF3D7_1222600; Gene product: AP2 domain transcription factor AP2-G (AP2-G; ApiAP2) Name tag: EGFP
Phenotype	Asexual bloodstage; Gametocyte/Gamete;

RMgm-5030

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1427700; Gene model (P.falciparum): PF3D7_0809700; Gene product: RuvB-like helicase 1 (RUVB1, RUVBL1, RvBL1) Name tag: mNeonGreen
Phenotype	Gametocyte/Gamete;

RMgm-5031

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1427700; Gene model (P.falciparum): PF3D7_0809700; Gene product: RuvB-like helicase 1 (RUVB1, RUVBL1, RvBL1)
Phenotype	Gametocyte/Gamete;

RMgm-5032

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0612400; Gene model (P.falciparum): PF3D7_0411000; Gene product: conserved Plasmodium protein, unknown function (AP2R-1, AP2-R1 (AP2 Transcription Factor-related gene 1), AP2-Z (AP2-zygote))
Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

RMgm-5033

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1418100; Gene model (P.falciparum): PF3D7_1319600; Gene product: ACDC domain-containing protein, putative (AP2R-2 (AP2 Transcription Factor-related gene 2))
Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

RMgm-5034

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0612400; Gene model (P.falciparum): PF3D7_0411000; Gene product: conserved Plasmodium protein, unknown function (AP2R-1, AP2-R1 (AP2 Transcription Factor-related gene 1), AP2-Z (AP2-zygote)) Name tag: mNeonGreen
Phenotype	Gametocyte/Gamete;

RMgm-5035

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1418100; Gene model (P.falciparum): PF3D7_1319600; Gene product: ACDC domain-containing protein, putative (AP2R-2 (AP2 Transcription Factor-related gene 2)) Name tag: mNeonGreen
Phenotype	Gametocyte/Gamete;

RMgm-5036

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_0938600; Gene model (P.falciparum): PF3D7_1111000; Gene product: tRNA m5C-methyltransferase, putative (NSUN2)
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5037

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_0804600; Gene model (P.falciparum): PF3D7_0704200; Gene product: tRNA m5C-methyltransferase, putative (NSUN1)
Phenotype	No phenotype has been described

RMgm-5038

Malaria parasite	P. yoelii
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PY17X_0920500; Gene model (P.falciparum): PF3D7_1129400; Gene product: rRNA (cytosine-C(5))-methyltransferase, putative (NOP2, NSUN3)
Phenotype	No phenotype has been described

RMgm-5039

Malaria parasite	P. yoelii
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PY17X_1447800; Gene model (P.falciparum): PF3D7_1230600; Gene product: sun-family protein, putative (NSUN4)
Phenotype	No phenotype has been described

RMgm-5040

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_0938600; Gene model (P.falciparum): PF3D7_1111000; Gene product: tRNA m5C-methyltransferase, putative (NSUN2) Name tag: 6xHA
Phenotype	No phenotype has been described

RMgm-5041

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1219500; Gene model (P.falciparum): PF3D7_0709000; Gene product: chloroquine resistance transporter (CRT) Details mutation: a mutated CRT with amino acid change N331I
Phenotype	Asexual bloodstage;

RMgm-5042

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1426700; Gene model (P.falciparum): PF3D7_0810800; Gene product: hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase putative (PPPK-DHPS, DHPS) Details mutation: a mutated DHPS with amino acid change A394G
Phenotype	Asexual bloodstage; Gametocyte/Gamete;

RMgm-5043

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1322200; Gene model (P.falciparum): PF3D7_1458500; Gene product: spindle assembly abnormal protein 4, putative (SAS4) Name tag: triple-HA
Phenotype	Gametocyte/Gamete;

RMgm-5044

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0106200; Gene model (P.falciparum): PF3D7_0607600; Gene product: spindle assembly abnormal protein 6, putative (SAS6) Name tag: triple-HA
Phenotype	Gametocyte/Gamete;

RMgm-5045

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1025100; Gene model (P.falciparum): PF3D7_1417600; Gene product: conserved Plasmodium protein, unknown function (oocyst capsule protein (OSCP))
Phenotype	Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

RMgm-5046

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_0809500; Gene model (P.falciparum): PF3D7_0319000; Gene product: P-type ATPase, putative (ATPase7)
Phenotype	Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5047

Malaria parasite	P. yoelii
Genotype
Mutated	Gene model (rodent): PY17X_0809500; Gene model (P.falciparum): PF3D7_0319000; Gene product: P-type ATPase, putative (ATPase7) Details mutation: In the atpase7 gene, E210 is replaced with Q
Phenotype	Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5048

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_0809500; Gene model (P.falciparum): PF3D7_0319000; Gene product: P-type ATPase, putative (ATPase7) Name tag: 6xHA
Phenotype	Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5049

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_0809500; Gene model (P.falciparum): PF3D7_0319000; Gene product: P-type ATPase, putative (ATPase7) Name tag: 4xMyc
Phenotype	Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-5050

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_0711800; Gene model (P.falciparum): PF3D7_0319000; Gene product: perforin-like protein 5 (PLP5, PPLP5, Plasmodium perforin-like protein 5; Membrane Attack Complex)
Phenotype	Fertilization and ookinete; Oocyst;

RMgm-5051

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_0415800; Gene model (P.falciparum): PF3D7_0315200; Gene product: circumsporozoite- and TRAP-related protein (CTRP)
Phenotype	Fertilization and ookinete; Oocyst;

RMgm-5052

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_1040200; Gene model (P.falciparum): PF3D7_1404300; Gene product: secreted ookinete adhesive protein, putative (SOAP) Name tag: 2A-GFP
Phenotype	Fertilization and ookinete; Oocyst;

RMgm-5053

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_1040200; Gene model (P.falciparum): PF3D7_1404300; Gene product: secreted ookinete adhesive protein, putative (SOAP) Name tag: 2A-mCherry
Phenotype	Fertilization and ookinete; Oocyst;

RMgm-5054

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_0514500; Gene model (P.falciparum): PF3D7_1029400; Gene product: LEM3/CDC50 family protein, putative (CDC50C) Name tag: AID degron motif
Transgene	Transgene not Plasmodium: the plant Oryza sativa auxin receptor transport inhibitor response 1 (TIR1) Promoter: Gene model: PY17X_1040200; Gene model (P.falciparum): PF3D7_1404300; Gene product: secreted ookinete adhesive protein, putative (soap) 3'UTR: Gene model: PY17X_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR-TS) Insertion locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein P230p
Phenotype	Fertilization and ookinete; Oocyst;

RMgm-5055

Malaria parasite	P. yoelii
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PY17X_0916600; Gene model (P.falciparum): PF3D7_1133300; Gene product: LEM3/CDC50 family protein, putative (CDC50c)
Phenotype	No phenotype has been described

RMgm-5056

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1310700; Gene model (P.falciparum): PF3D7_1446900; Gene product: glutaminyl-peptide cyclotransferase, putative (glutamyl cyclase, QC)
Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene	Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p)
Phenotype	Oocyst; Sporozoite; Liver stage;

RMgm-5057

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1310700; Gene model (P.falciparum): PF3D7_1446900; Gene product: glutaminyl-peptide cyclotransferase, putative (glutamyl cyclase, QC)
Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene	Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p)
Phenotype	Oocyst; Sporozoite; Liver stage;

RMgm-5058

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1310700; Gene model (P.falciparum): PF3D7_1446900; Gene product: glutaminyl-peptide cyclotransferase, putative (glutamyl cyclase, QC)
Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene	Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p)
Phenotype	Oocyst; Sporozoite; Liver stage;

all	gene disrupted	gene mutated / conditional mutagenesis	gene tagged	gene transgene all transgene promoter 3'UTR	gene other

all	gene disrupted	gene mutated / conditional mutagenesis	gene tagged	gene other

all	gene disrupted	gene mutated / conditional mutagenesis	gene tagged	gene transgene all transgene promoter 3'UTR	gene other

all	gene disrupted	gene mutated / conditional mutagenesis	gene tagged	gene transgene	gene other

RMgmDB - Rodent Malaria genetically modified Parasites

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