Search database by RMgm ID
RMgm-4857
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0943400; Gene model (P.falciparum): PF3D7_1103500; Gene product: CPW-WPC family protein (CPW1) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4858
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1015400; Gene model (P.falciparum): PF3D7_1429300; Gene product: CPW-WPC family protein (CPW4) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4859
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1449300; Gene model (P.falciparum): PF3D7_1234700; Gene product: upregulated in late gametocytes ULG8 (CPW-WPC family protein; CPW2) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4860
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1218300; Gene model (P.falciparum): PF3D7_0320200; Gene product: CPW-WPC family protein (CPW3) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4861
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0704900; Gene model (P.falciparum): PF3D7_0825700; Gene product: crystalloid-specific PH domain-containing protein, putative (CryPH, PH-like (PHL) domain-containing protein; PHL3) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4862
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0417200; Gene model (P.falciparum): PF3D7_0904200; Gene product: PH domain-containing protein, putative (PH, PH-like (PHL) domain-containing protein; PHL1) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4863
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0704800; Gene model (P.falciparum): PF3D7_0825800; Gene product: conserved protein, unknown function (PH-like (PHL) domain-containing protein; PHL2) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4864
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0902900; Gene model (P.falciparum): PF3D7_1146100; Gene product: conserved protein, unknown function (PH-like (PHL) domain-containing protein; PHL4) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4865
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1104100; Gene model (P.falciparum): PF3D7_0504500; Gene product: MOLO1 domain-containing protein, putative (TPM2) Name tag: GFP |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4866
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Details mutation: 'promoter-swap' mutant; the RON4 promoter replaced by the promoter of PBANKA_1443300 (msp9) |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4867
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_0713100; Gene model (P.falciparum): PF3D7_0817700; Gene product: rhoptry neck protein 5 (RON5) Details mutation: 'promoter-swap' mutant; the RON5 promoter replaced by the promoter of PBANKA_1443300 (msp9) |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; |
RMgm-4868
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Details mutation: C-terminal tagging of CDPK4 with the AID-2xHA degron |
| Transgene |
Transgene not Plasmodium: (myc-tagged) Os-TIR1 protein Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0514900; Gene product: 28 kDa ookinete surface protein (P28) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4869
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_1351500; Gene model (P.falciparum): PF3D7_1337800; Gene product: calcium-dependent protein kinase 5 (CDPK5) Details mutation: C-terminal tagging of CDPK5 with the AID-2xHA degron |
| Transgene |
Transgene not Plasmodium: (myc-tagged) Os-TIR1 protein Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0514900; Gene product: 28 kDa ookinete surface protein (P28) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4870
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene not Plasmodium: Cas9 from Streptococcus pyogenes Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
| Phenotype |
Oocyst;
|
RMgm-4871
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0304800; Gene model (P.falciparum): PF3D7_0207400; Gene product: serine repeat antigen 7 (serine repeat antigen 7, SERA7, SERA4) |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Liver stage; |
RMgm-4872
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0304800; Gene model (P.falciparum): PF3D7_0207400; Gene product: serine repeat antigen 7 (serine repeat antigen 7, SERA7, SERA4) Name tag: mCherry |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Sporozoite; Liver stage; |
RMgm-4873
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1346500; Gene model (P.falciparum): PF3D7_1331600; Gene product: protein tyrosine phosphatase-like protein, putative (PTPLA; 3-hydroxyacyl-CoA dehydratase; DEH) |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Oocyst;
Sporozoite; |
RMgm-4874
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0807700; Gene model (P.falciparum): PF3D7_0317500; Gene product: kinesin-5 (EG5) |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4875
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0807700; Gene model (P.falciparum): PF3D7_0317500; Gene product: kinesin-5 (EG5) Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-4876
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0205600; Gene model (P.falciparum): PF3D7_0107800; Gene product: double-strand break repair protein MRE11 (MRE11) |
| Phenotype |
Oocyst;
Sporozoite; |
RMgm-4877
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0205600; Gene model (P.falciparum): PF3D7_0107800; Gene product: double-strand break repair protein MRE11 (MRE11) Name tag: GFP |
| Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-4878
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_1356700; Gene model (P.falciparum): PF3D7_1343700; Gene product: kelch protein K13 (Kelch13) Details mutation: Several mutations in K13 associated with artemisinin resistance |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Asexual bloodstage;
|
RMgm-4879
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0614300; Gene model (P.falciparum): PF3D7_0716600; Gene product: cysteine desulfurase (SufS) |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Asexual bloodstage;
|
RMgm-4880
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_1122100; Gene model (P.falciparum): PF3D7_0623200; Gene product: ferredoxin--NADP reductase (FNR) Details mutation: FNR promoter replaced by eef1a promoter |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Asexual bloodstage;
|
RMgm-4881
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0931500; Gene model (P.falciparum): PF3D7_1116500; Gene product: folate transporter 2 (FT2) |
| Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (Dhfs-fpgs) Replacement locus: Gene model: PBANKA_0931500; Gene product: folate transporter 2 (FT2) |
| Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4882
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0931500; Gene model (P.falciparum): PF3D7_1116500; Gene product: folate transporter 2 (FT2) Name tag: mCherry-3xMyc |
| Transgene |
Transgene not Plasmodium: GFP tagged to CPN20, PBANKA_1347800 Promoter: Gene model: PBANKA_1347800; Gene model (P.falciparum): PF3D7_1333000; Gene product: 20 kDa chaperonin (CPN20) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_0931500; Gene product: folate transporter 2 (FT2) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Oocyst;
Sporozoite; |
RMgm-4883
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_0719300; Gene model (P.falciparum): PF3D7_0417200; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) Details mutation: Pbdhfr/ts replaced with a mutated P. falciparum dhfr/ts (N51I, C59R, S108N, I164L) |
| Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Asexual bloodstage;
|
RMgm-4884
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1037800; Gene model (P.falciparum): PF3D7_1404300; Gene product: secreted ookinete adhesive protein, putative (SOAP) Name tag: APEX2 + cmyc |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4885
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1105300; Gene model (P.falciparum): PF3D7_0505700; Gene product: conserved Plasmodium membrane protein, unknown function (akratin) |
| Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_1105300; Gene product: conserved Plasmodium membrane protein, unknown function (akratin) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-4886
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_1105300; Gene model (P.falciparum): PF3D7_0505700; Gene product: conserved Plasmodium membrane protein, unknown function (akratin) Details mutation: C-terminal EYKK motif changed into four alanines and GFP tag |
| Phenotype |
Gametocyte/Gamete;
Oocyst;
|
RMgm-4887
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_1105300; Gene model (P.falciparum): PF3D7_0505700; Gene product: conserved Plasmodium membrane protein, unknown function (akratin) Details mutation: P. berghei akratin gene replaced with P. falciparum akratin gene with a GFP tag |
| Phenotype | No phenotype has been described |
RMgm-4888
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1105300; Gene model (P.falciparum): PF3D7_0505700; Gene product: conserved Plasmodium membrane protein, unknown function (akratin) Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-4889
| Malaria parasite | P. yoelii |
| Genotype | |
| Disrupted | Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1) |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4890
| Malaria parasite | P. yoelii |
| Genotype | |
| Disrupted | Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4891
| Malaria parasite | P. yoelii |
| Genotype | |
| Disrupted | Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1) |
| Disrupted | Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4892
| Malaria parasite | P. yoelii |
| Genotype | |
| Mutated | Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1) Details mutation: N-terminal cysteines (C7/C8) replaced with A7/A8 (alanine) and C-terminal BFP::3V5 tag |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4893
| Malaria parasite | P. yoelii |
| Genotype | |
| Tagged | Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1) Name tag: sextuple HA epitope (6HA) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-4894
| Malaria parasite | P. yoelii |
| Genotype | |
| Tagged | Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) Name tag: sextuple HA epitope (6HA) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-4895
| Malaria parasite | P. yoelii |
| Genotype | |
| Tagged | Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) Name tag: sextuple HA epitope (6HA) |
| Tagged | Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1) Name tag: 3xV5 |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4896
| Malaria parasite | P. yoelii |
| Genotype | |
| Tagged | Gene model (rodent): PY17X_0109900; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2) Name tag: sextuple HA epitope (6HA) |
| Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4897
| Malaria parasite | P. yoelii |
| Genotype | |
| Genetic modification not successful | |
| Disrupted | Gene model (rodent): PY17X_0109900; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2) |
| Phenotype | No phenotype has been described |
RMgm-4898
| Malaria parasite | P. yoelii |
| Genotype | |
| Mutated | Gene model (rodent): PY17X_0109900; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2) Details mutation: 'promoter-swap' mutant; the promoter of DHHC2 replaced by the promoter of PY17X_1402200 (clag) |
| Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-4899
| Malaria parasite | P. yoelii |
| Genotype | |
| Mutated | Gene model (rodent): PY17X_0109900; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2) Details mutation: Glycine 128 changed to alanine |
| Tagged | Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1) Name tag: sextuple HA epitope (6HA) |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4900
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene not Plasmodium: DiCre Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): heat shock protein 70; Gene product: HSP70 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype | No phenotype has been described |
RMgm-4901
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: A series of mutants expressing an additional copy of CSP, tagged with GFP at different locations |
| Tagged | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Name tag: GFP |
| Phenotype |
Oocyst;
Sporozoite; |
RMgm-4902
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0204700; Gene model (P.falciparum): PF3D7_0204700; Gene product: hexose transporter (HT1) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4903
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_1137800; Gene model (P.falciparum): PF3D7_1137800; Gene product: sporozoite surface protein essential for liver stage development, putative (SPELD) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4904
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0830300; Gene model (P.falciparum): PF3D7_0830300; Gene product: sporozoite invasion-associated protein 2 (SIAP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4905
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0212600; Gene model (P.falciparum): PF3D7_0212600; Gene product: secreted protein with altered thrombospondin repeat domain (SPATR) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4906
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_1027800; Gene model (P.falciparum): PF3D7_1027800; Gene product: 60S ribosomal protein L3 (RPL3) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4907
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_1016900; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 (ETRAMP10.3) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4908
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_1449000; Gene model (P.falciparum): PF3D7_1449000; Gene product: gamete egress and sporozoite traversal protein, putative (GEST) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4910
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0812300; Gene model (P.falciparum): PF3D7_0812300; Gene product: sporozoite surface protein 3, putative (SSP3) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4911
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0408600; Gene model (P.falciparum): PF3D7_0408600; Gene product: sporozoite invasion-associated protein 1 (SIAP1) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4912
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0404400; Gene model (P.falciparum): PF3D7_0404400; Gene product: 6-cysteine protein P36 (P36) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4913
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0404500; Gene model (P.falciparum): PF3D7_0404500; Gene product: 6-cysteine protein P52 (P52, P36p) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4914
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0408700; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 (PLP1, PPLP1, SPECT2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4915
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_1147800; Gene model (P.falciparum): PF3D7_1147800; Gene product: membrane associated erythrocyte binding-like protein (MAEBL) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (S1) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4916
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene Plasmodium: Gene model: PF3D7_0317100; Gene model (P.falciparum): PF3D7_0317100; Gene product: 6-cysteine protein (B9) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (S1) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4917
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_0808100; Gene model (P.falciparum): PF3D7_0317100; Gene product: 6-cysteine protein (B9) Details mutation: The endogenous P. berghei b9 gene replaced with the P. falciparum b9 ortholog |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4918
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1006300; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 (PLP1, PPLP1, SPECT2) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; |
RMgm-4919
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PF3D7_0408700; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 (PLP1, PPLP1, SPECT2) Details mutation: The endogenous P. berghei plp1/spect2 gene replaced with the P. falciparum plp1/spect2 ortholog |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Sporozoite; Liver stage; |
RMgm-4920
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1206800; Gene model (P.falciparum): PF3D7_1008600; Gene product: zinc finger (CCCH type) protein, putative (S1) |
| Transgene |
Transgene not Plasmodium: Ovalbumin (OVA ) fused to HEP17/EXP1 Promoter: Gene model: PBANKA_0926700; Gene model (P.falciparum): PF3D7_1121600; Gene product: exported protein 1 | circumsporozoite-related antigen | parasitophorous vacuole membrane antigen QF 116 (HEP17; EXP1) 3'UTR: Gene model: PBANKA_0926700; Gene product: exported protein 1, putative circumsporozoite-related antigen (HEP17; EXP1) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype | No phenotype has been described |
RMgm-4921
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene not Plasmodium: Ovalbumin (OVA ) fused to HEP17/EXP1 Promoter: Gene model: PBANKA_0926700; Gene model (P.falciparum): PF3D7_1121600; Gene product: exported protein 1 | circumsporozoite-related antigen | parasitophorous vacuole membrane antigen QF 116 (HEP17; EXP1) 3'UTR: Gene model: PBANKA_0926700; Gene product: exported protein 1, putative circumsporozoite-related antigen (HEP17; EXP1) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (s1) |
| Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-4922
| Malaria parasite | P. berghei |
| Genotype | |
| Transgene |
Transgene not Plasmodium: Ovalbumin (OVA ) fused to HEP17/EXP1 Promoter: Gene model: PBANKA_0926700; Gene model (P.falciparum): PF3D7_1121600; Gene product: exported protein 1 | circumsporozoite-related antigen | parasitophorous vacuole membrane antigen QF 116 (HEP17; EXP1) 3'UTR: Gene model: PBANKA_0926700; Gene product: exported protein 1, putative circumsporozoite-related antigen (HEP17; EXP1) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (s1) |
| Phenotype |
Asexual bloodstage;
|
RMgm-4923
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0305900; Gene model (P.falciparum): PF3D7_0208800; Gene product: conserved Plasmodium protein, unknown function (pb22) |
| Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-4924
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0305900; Gene model (P.falciparum): PF3D7_0208800; Gene product: conserved Plasmodium protein, unknown function (pb22) Name tag: HA |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4925
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_1400800; Gene model (P.falciparum): PF3D7_1302200; Gene product: early transcribed membrane protein 13 (ETRAMP13, UIS3) Details mutation: The P. berghei uis3 gene replaced with HA-tagged uis3 gene of P. falciparum |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Liver stage; |
RMgm-4926
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PY17X_0822200; Gene model (P.falciparum): PF3D7_0917900; Gene product: heat shock protein 70 (BIP) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Asexual bloodstage;
|
RMgm-4927
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PY17X_1402200; Gene model (P.falciparum): Not available; Gene product: cytoadherence linked asexual protein, putative (RhopH1A, clag-a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Liver stage; |
RMgm-4928
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PY17X_0418900; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative (dd) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
|
RMgm-4929
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PY17X_1323300; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (CCp2, LAP4) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
|
RMgm-4930
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PY17X_1354800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein (TRAP) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Gametocyte/Gamete;
Oocyst;
Sporozoite; |
RMgm-4931
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PY17X_0502200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 (UIS4) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-4932
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PY17X_1004400; Gene model (P.falciparum): PF3D7_0405300; Gene product: liver specific protein 2, putative (LISP2) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Gametocyte/Gamete;
Liver stage; |
RMgm-4933
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0800500; Gene model (P.falciparum): PF3D7_1252200; Gene product: chitinase (CHT1) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype | No phenotype has been described |
RMgm-4934
| Malaria parasite | P. berghei |
| Genotype | |
| Mutated | Gene model (rodent): PBANKA_0800500; Gene model (P.falciparum): PF3D7_1252200; Gene product: chitinase (CHT1) Details mutation: The P. berghei cht1 gene replaced by the cht1 gene of P. falciparum |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype | No phenotype has been described |
RMgm-4935
| Malaria parasite | P. yoelii |
| Genotype | |
| Disrupted | Gene model (rodent): PY17X_0405400; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CS; CSP) |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p; 230) |
| Phenotype |
Oocyst;
Sporozoite; |
RMgm-4936
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CS; CSP) |
| Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Oocyst;
Sporozoite; |
RMgm-4937
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1122300; Gene model (P.falciparum): PF3D7_0623400; Gene product: MEI2-like RNA-binding protein (Mei2) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Liver stage; |
RMgm-4938
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1024600; Gene model (P.falciparum): PF3D7_1418100; Gene product: liver specific protein 1, putative (LISP1) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
| Phenotype | No phenotype has been described |
RMgm-4939
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1122300; Gene model (P.falciparum): PF3D7_0623400; Gene product: MEI2-like RNA-binding protein (Mei2) |
| Disrupted | Gene model (rodent): PBANKA_1024600; Gene model (P.falciparum): PF3D7_1418100; Gene product: liver specific protein 1, putative (LISP1) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Liver stage; |
RMgm-4940
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1122300; Gene model (P.falciparum): PF3D7_0623400; Gene product: MEI2-like RNA-binding protein (Mei2) |
| Disrupted | Gene model (rodent): PBANKA_0101100; Gene model (P.falciparum): PF3D7_0602300; Gene product: liver merozoite formation protein, putative (PALM) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Liver stage; |
RMgm-4941
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1122300; Gene model (P.falciparum): PF3D7_0623400; Gene product: MEI2-like RNA-binding protein (Mei2) |
| Disrupted | Gene model (rodent): PBANKA_1003000; Gene model (P.falciparum): PF3D7_0405300; Gene product: liver specific protein 2, putative (LISP2) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Liver stage; |
RMgm-4942
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1024600; Gene model (P.falciparum): PF3D7_1418100; Gene product: liver specific protein 1, putative (LISP1) |
| Disrupted | Gene model (rodent): PBANKA_0101100; Gene model (P.falciparum): PF3D7_0602300; Gene product: liver merozoite formation protein, putative (PALM) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Liver stage; |
RMgm-4943
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_1024600; Gene model (P.falciparum): PF3D7_1418100; Gene product: liver specific protein 1, putative (LISP1) |
| Disrupted | Gene model (rodent): PBANKA_1003000; Gene model (P.falciparum): PF3D7_0405300; Gene product: liver specific protein 2, putative (LISP2) |
| Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
| Phenotype |
Liver stage; |
RMgm-4944
| Malaria parasite | P. yoelii |
| Genotype | |
| Mutated | Gene model (rodent): PY17X_0405400; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. yoelii csp gene replaced by P. falciparum csp |
| Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p; 230) |
| Phenotype | No phenotype has been described |
RMgm-4945
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: the plant Oryza sativa auxin receptor transport inhibitor response 1 (TIR1) Promoter: Gene model: PY17X_1134900; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PY17X_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR-TS) Insertion locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein P230p |
| Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4946
| Malaria parasite | P. yoelii |
| Genotype | |
| Transgene |
Transgene not Plasmodium: the plant Oryza sativa auxin receptor transport inhibitor response 1 (TIR1) Promoter: Gene model: PY17X_1040200; Gene model (P.falciparum): PF3D7_1404300; Gene product: secreted ookinete adhesive protein, putative (soap) 3'UTR: Gene model: PY17X_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR-TS) Insertion locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein P230p |
| Phenotype |
Fertilization and ookinete;
|
RMgm-4947
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1025300; Gene model (P.falciparum): PF3D7_1417400; Gene product: rap guanine nucleotide exchange factor, putative, pseudogene (EPAC) Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4948
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1313300; Gene model (P.falciparum): PF3D7_1449600; Gene product: conserved protein, unknown function Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4949
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1347000; Gene model (P.falciparum): PF3D7_1332200; Gene product: conserved protein, unknown function Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4950
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1419000; Gene model (P.falciparum): PF3D7_1320700; Gene product: conserved protein, unknown function Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4951
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0109800; Gene model (P.falciparum): PF3D7_0611500; Gene product: conserved protein, unknown function Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4952
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0907700; Gene model (P.falciparum): PF3D7_1141300; Gene product: conserved protein, unknown function Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4953
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_0310700; Gene model (P.falciparum): PF3D7_0213800; Gene product: conserved protein, unknown function Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4954
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1216300; Gene model (P.falciparum): PF3D7_0322200; Gene product: conserved protein, unknown function Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4955
| Malaria parasite | P. berghei |
| Genotype | |
| Tagged | Gene model (rodent): PBANKA_1334800; Gene model (P.falciparum): PF3D7_1471600; Gene product: conserved protein, unknown function Name tag: GFP |
| Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Sporozoite; |
RMgm-4956
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0506200; Gene model (P.falciparum): PF3D7_1022000; Gene product: RNA-binding protein, putative (UIS12) |
| Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
| Phenotype |
Gametocyte/Gamete;
Oocyst;
Sporozoite; |
RMgm-4957
| Malaria parasite | P. berghei |
| Genotype | |
| Disrupted | Gene model (rodent): PBANKA_0202700; Gene model (P.falciparum): PF3D7_0111000; Gene product: kinesin-8B, putative |
| Phenotype |
Gametocyte/Gamete;
|