Search database by RMgm ID
RMgm-5159
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0617900; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (cdpk4) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5160
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1440500; Gene model (P.falciparum): PF3D7_1223100; Gene product: cAMP-dependent protein kinase regulatory subunit (PKAr) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5161
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0839000; Gene model (P.falciparum): PF3D7_0934800; Gene product: cAMP-dependent protein kinase catalytic subunit (PKAc) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5162
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1420600; Gene model (P.falciparum): PF3D7_1320600; Gene product: ras-related protein Rab-11A (RAB11A) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5163
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1462100; Gene model (P.falciparum): PF3D7_1246400; Gene product: myosin light chain 1 | myosin A tail domain interacting protein (MTIP) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5164
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0206000; Gene model (P.falciparum): PF3D7_0109000; Gene product: photosensitized INA-labeled protein PHIL1, putative (PHIL1) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5165
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0525300; Gene model (P.falciparum): PF3D7_0423500; Gene product: glideosome associated protein with multiple membrane spans 2, putative (GAPM2) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5166
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0312400; Gene model (P.falciparum): PF3D7_0215100; Gene product: zinc finger protein, putative Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5167
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0418000; Gene model (P.falciparum): PF3D7_0906100; Gene product: vacuolar protein sorting-associated protein 46, putative Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5168
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0812700; Gene model (P.falciparum): PF3D7_0908000; Gene product: plasma membrane protein 1, putative (PMP1) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5169
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1131200; Gene model (P.falciparum): PF3D7_0631000; Gene product: tetratricopeptide repeat protein, putative Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5170
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1139700; Gene model (P.falciparum): PF3D7_1362300; Gene product: transmembrane and coiled-coil domain-containing protein 1, putative (TMCO1) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5171
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1220300; Gene model (P.falciparum): PF3D7_0321400; Gene product: pseudo protein kinase 1, putative (pPK1) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5172
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1348200; Gene model (P.falciparum): PF3D7_1328300; Gene product: conserved protein, unknown function Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5173
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1359500; Gene model (P.falciparum): PF3D7_1340700; Gene product: ras-related protein Rab-11B (RAB11b) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5174
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1411000; Gene model (P.falciparum): PF3D7_1310700; Gene product: PhIL1-interacting candidate PIC5 Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5175
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1441500; Gene model (P.falciparum): PF3D7_1224100; Gene product: conserved protein, unknown function Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5176
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_1453100; Gene model (P.falciparum): PF3D7_1236000; Gene product: vesicle transport v-SNARE protein VTI1, putative Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5177
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0207400; Gene model (P.falciparum): PF3D7_0107400; Gene product: ATP synthase-associated protein, putative Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5178
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0417300; Gene model (P.falciparum): PF3D7_0316700; Gene product: protein YOP1, putative (YOP1) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5179
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0917100; Gene model (P.falciparum): PF3D7_1132800; Gene product: aquaglyceroporin (AQP) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5180
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene not Plasmodium: HA-tagged TurboID fused with an IMC signal peptide Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-5181
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0108300; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2) Name tag: AID degron motif (mAID-2HA) |
Transgene |
Transgene not Plasmodium: the plant Oryza sativa auxin receptor transport inhibitor response 1 (TIR1) Promoter: Gene model: PY17X_1134900; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PY17X_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR-TS) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein P230p |
Phenotype |
Asexual bloodstage;
|
RMgm-5182
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1302300; Gene model (P.falciparum): PF3D7_1438400; Gene product: metacaspase-2 (MCA2, MCA-2) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-5183
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0309500; Gene model (P.falciparum): PF3D7_0212600; Gene product: secreted protein with altered thrombospondin repeat domain (SPATR) |
Phenotype | No phenotype has been described |
RMgm-5184
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0309500; Gene model (P.falciparum): PF3D7_0212600; Gene product: secreted protein with altered thrombospondin repeat domain (SPATR) |
Mutated | Gene model (rodent): PBANKA_0309500; Gene model (P.falciparum): PF3D7_0212600; Gene product: secreted protein with altered thrombospondin repeat domain (SPATR) Details mutation: 'promoter-swap' mutant; spatr gene with the promoter of PBANKA_0603900 (hado) in neutral SIL6 locus |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-5185
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0309500; Gene model (P.falciparum): PF3D7_0212600; Gene product: secreted protein with altered thrombospondin repeat domain (SPATR) Name tag: c-myc |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; |
RMgm-5186
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1218500; Gene model (P.falciparum): PF3D7_0320000; Gene product: protein phosphatase inhibitor 2 (PbI2, I2) Name tag: mCherry |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
|
RMgm-5187
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. berghei csp gene replaced by P. falciparum csp |
Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-5188
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0701900; Gene model (P.falciparum): PF3D7_0828800; Gene product: GPI-anchored micronemal antigen (GAMA, Putative Secreted Ookinete Protein 9, PSOP9) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-5189
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0701900; Gene model (P.falciparum): PF3D7_0828800; Gene product: GPI-anchored micronemal antigen (GAMA, Putative Secreted Ookinete Protein 9, PSOP9) Details mutation: The P. berghei gama gene replaced by the P. falciparum gama gene |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-5190
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0701900; Gene model (P.falciparum): PF3D7_0828800; Gene product: GPI-anchored micronemal antigen (GAMA, Putative Secreted Ookinete Protein 9, PSOP9) Name tag: mCherry |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-5191
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0701900; Gene model (P.falciparum): PF3D7_0828800; Gene product: GPI-anchored micronemal antigen (GAMA, Putative Secreted Ookinete Protein 9, PSOP9) Details mutation: the promoter of the gama gene replaced by the promoter of the ctrp gene (PBANKA_0412900) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-5192
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1001800; Gene model (P.falciparum): PF3D7_0404100; Gene product: AP2 domain transcription factor AP2-SP2, putative (ApiAP2; AP2-SP2) Details mutation: AP2-Sp binding motifs mutated in the upstream region of the AP2-Sp2 gene |
Transgene |
Transgene not Plasmodium: Cas9 from Streptococcus pyogenes Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-5193
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1003000; Gene model (P.falciparum): PF3D7_0405300; Gene product: liver specific protein 2, putative (LISP2) Name tag: Cre recombinase |
Phenotype |
Liver stage; |
RMgm-5194
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1422900; Gene model (P.falciparum): PF3D7_0814600; Gene product: PIMMS22 protein, putative (SIMP, sporozoite structural integrity maintenance protein) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_1422900; Gene product: PIMMS22 protein, putative (SIMP, sporozoite structural integrity maintenance protein) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-5195
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1422900; Gene model (P.falciparum): PF3D7_0814600; Gene product: PIMMS22 protein, putative (SIMP, sporozoite structural integrity maintenance protein) Name tag: triple-HA |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-5196
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1429300; Gene model (P.falciparum): PF3D7_1213500; Gene product: integral membrane protein GPR180, putative (GPR180) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-5197
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1429300; Gene model (P.falciparum): PF3D7_1213500; Gene product: integral membrane protein GPR180, putative (GPR180) Name tag: triple-HA |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-5198
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1429300; Gene model (P.falciparum): PF3D7_1213500; Gene product: integral membrane protein GPR180, putative (GPR180) Details mutation: The endogenous P. berghei gpr180 gene replaced with the grp180 ortholog of P. vivax (PVX_123365) |
Phenotype | No phenotype has been described |
RMgm-5199
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0612400; Gene model (P.falciparum): PF3D7_0411000; Gene product: conserved Plasmodium protein, unknown function (AP2R-1, AP2-R1 (AP2 Transcription Factor-related gene 1), AP2-Z (AP2-zygote)) Name tag: GFP |
Transgene |
Transgene not Plasmodium: Cas9 from Streptococcus pyogenes Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Fertilization and ookinete;
|
RMgm-5200
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0612400; Gene model (P.falciparum): PF3D7_0411000; Gene product: conserved Plasmodium protein, unknown function (AP2R-1, AP2-R1 (AP2 Transcription Factor-related gene 1), AP2-Z (AP2-zygote)) Details mutation: Disruption of AP2-binding motifs (AP2-G, AP2-FG) upstream of AP2-Z (PBANKA_0612400) |
Tagged | Gene model (rodent): PBANKA_0612400; Gene model (P.falciparum): PF3D7_0411000; Gene product: conserved Plasmodium protein, unknown function (AP2R-1, AP2-R1 (AP2 Transcription Factor-related gene 1), AP2-Z (AP2-zygote)) Name tag: GFP |
Transgene |
Transgene not Plasmodium: Cas9 from Streptococcus pyogenes Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Fertilization and ookinete;
|
RMgm-5201
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0508300; Gene model (P.falciparum): PF3D7_1024100; Gene product: conserved Plasmodium protein, unknown function (OMG1, ookinete maturation gene 1) Name tag: mNeonGreen fluorescent protein (mNG) |
Transgene |
Transgene not Plasmodium: Cas9 from Streptococcus pyogenes Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Fertilization and ookinete;
|
RMgm-5202
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0508300; Gene model (P.falciparum): PF3D7_1024100; Gene product: conserved Plasmodium protein, unknown function (OMG1, ookinete maturation gene 1) |
Transgene |
Transgene not Plasmodium: Cas9 from Streptococcus pyogenes Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit)) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-5203
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1423100; Gene model (P.falciparum): PF3D7_0814400; Gene product: putative phospholipase, DDHD1 (PA-PLA1, Pla1) |
Phenotype |
Liver stage; |
RMgm-5204
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1423100; Gene model (P.falciparum): PF3D7_0814400; Gene product: putative phospholipase, DDHD1 (PA-PLA1, Pla1) Name tag: 3XHA-mCherry |
Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-5205
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1241900; Gene model (P.falciparum): PF3D7_0527100; Gene product: ubiquitin-conjugating enzyme E2 13, putative (UBC13) Name tag: mCherry |
Phenotype |
Asexual bloodstage;
Oocyst;
Sporozoite; Liver stage; |
RMgm-5206
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1413600; Gene model (P.falciparum): PF3D7_1315100; Gene product: serine/threonine protein kinase PK9 |
Phenotype | No phenotype has been described |
RMgm-5207
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1413600; Gene model (P.falciparum): PF3D7_1315100; Gene product: serine/threonine protein kinase PK9 Name tag: triple-HA |
Phenotype |
Asexual bloodstage;
Sporozoite; Liver stage; |
RMgm-5208
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Mutated | Gene model (rodent): PBANKA_1241900; Gene model (P.falciparum): PF3D7_0527100; Gene product: ubiquitin-conjugating enzyme E2 13, putative (UBC13) Details mutation: the phosphorylating serine 106 replaced with with non-phosphorylatable alanine |
Phenotype | No phenotype has been described |
RMgm-5209
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1224500; Gene model (P.falciparum): PF3D7_0806200; Gene product: Dpy-19-like C-mannosyltransferase (CmanT, DPY19) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-5210
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0501200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 | protein of early gametocyte 4 (UIS4; ETRAMP10.3) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-5211
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1322200; Gene model (P.falciparum): PF3D7_1458500; Gene product: spindle assembly abnormal protein 4, putative (SAS4) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-5212
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1322200; Gene model (P.falciparum): PF3D7_1458500; Gene product: spindle assembly abnormal protein 4, putative (SAS4) Name tag: GFP |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-5213
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1457700; Gene model (P.falciparum): PF3D7_1244500; Gene product: PIMMS57 protein (PSOP26) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-5214
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1457700; Gene model (P.falciparum): PF3D7_1244500; Gene product: PIMMS57 protein (PSOP26) Name tag: triple-HA |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-5215
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0901300; Gene model (P.falciparum): PF3D7_1147800; Gene product: membrane associated erythrocyte binding-like protein (MAEBL) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-5216
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0901300; Gene model (P.falciparum): PF3D7_1147800; Gene product: membrane associated erythrocyte binding-like protein (MAEBL) Name tag: c-myc |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; |
RMgm-5217
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0519800; Gene model (P.falciparum): PF3D7_1036800; Gene product: acetyl-CoA transporter, putative (ACT, acetyl-CoA transporter 1, AT1) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
|
RMgm-5218
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1409100; Gene model (P.falciparum): PF3D7_1310600; Gene product: ras-related protein Rab-5B (RAB5b; secretory complex protein 61 alpha; Sec61-alpha; Rab GTPase 5b) Name tag: HA |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-5219
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1409100; Gene model (P.falciparum): PF3D7_1310600; Gene product: ras-related protein Rab-5B (RAB5b; secretory complex protein 61 alpha; Sec61-alpha; Rab GTPase 5b) Details mutation: Rab5b with the mutation Q91L (GTPase deficient) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-5220
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PbANKA_1343400; Gene model (P.falciparum): PF3D7_1328200; Gene product: conserved Plasmodium protein, unknown function (BRCA2; breast cancer susceptibility protein 2) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Insertion locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-5221
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene not Plasmodium: RFP (RedStar) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit)) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-5222
Malaria parasite | P. yoelii |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: Pexel I and II domains of CSP were mutated into ANANA and ALAGA |
Transgene |
Transgene not Plasmodium: RFP (RedStar) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit)) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-5223
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1450200; Gene model (P.falciparum): PF3D7_1235600; Gene product: Serine hydroxymethyltransferase, putative (SHMT) |
Phenotype | No phenotype has been described |
RMgm-5224
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1450200; Gene model (P.falciparum): PF3D7_1235600; Gene product: Serine hydroxymethyltransferase, putative (SHMT) Details mutation: The P. berghei shmt gene replaced with the P. vivax shmt gene (PVX_100730) |
Phenotype |
Asexual bloodstage;
|
RMgm-5225
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0524300; Gene model (P.falciparum): Not available; Gene product: tryptophan-rich protein (IPIS2, intra-erythrocytic Plasmodium-induced structure protein 2) |
Phenotype |
Asexual bloodstage;
|
RMgm-5226
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0623100; Gene model (P.falciparum): Not available; Gene product: tryptophan-rich protein (IPIS3, intra-erythrocytic Plasmodium-induced structure protein 3) |
Phenotype |
Asexual bloodstage;
|
RMgm-5227
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0524300; Gene model (P.falciparum): Not available; Gene product: tryptophan-rich protein (IPIS2, intra-erythrocytic Plasmodium-induced structure protein 2) Name tag: mCherry |
Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-5228
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0623100; Gene model (P.falciparum): Not available; Gene product: tryptophan-rich protein (IPIS3, intra-erythrocytic Plasmodium-induced structure protein 3) Name tag: mCherry |
Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-5229
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1400700; Gene model (P.falciparum): Not available; Gene product: Plasmodium exported protein, unknown function Name tag: mCherry |
Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-5230
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1459300; Gene model (P.falciparum): PF3D7_1246200; Gene product: actin I (ACT1; actin1) Details mutation: Different mutants are described with different point mutations in (subdomains of) actin 1 |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-5231
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0516600; Gene model (P.falciparum): PF3D7_1032800; Gene product: leucine-rich repeat protein (PbLRR1) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-5232
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0516600; Gene model (P.falciparum): PF3D7_1032800; Gene product: leucine-rich repeat protein (PbLRR1) Name tag: mCherry |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-5233
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0802000; Gene model (P.falciparum): PF3D7_0704300; Gene product: conserved Plasmodium membrane protein, unknown function (BLEB (basolateral expansion boundary)) Name tag: GFP |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
|
RMgm-5234
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0209900; Gene model (P.falciparum): PF3D7_0103200; Gene product: nucleoside transporter 4 (NT4) |
Transgene |
Transgene not Plasmodium: mTurquoise2 fluorescent protein Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0209900; Gene product: nucleoside transporter 4 (NT4) Replacement locus: Gene model: PBANKA_0209900; Gene product: nucleoside transporter 4 (NT4) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-5235
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CS; CSP) Details mutation: P. berghei csp replaced with the 'P. vivax like' csp (locus PVU09738). |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-5236
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: Not available; Gene model (P.falciparum): Not available; Gene product: 'P. vivax like' csp (locus PVU09738; Accession U09738) (PvCSP, G10) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-5237
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Phenotype |
Sporozoite; |
RMgm-5238
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: P. berghei trap replaced with different mutated forms of trap (point mutations) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-5239
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0417900; Gene model (P.falciparum): PF3D7_0903500; Gene product: nucleoporin NUP138, putative (NUP138) Name tag: TurboID-3XHA |
Phenotype |
Asexual bloodstage;
|
RMgm-5240
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1310200; Gene model (P.falciparum): PF3D7_1446500; Gene product: nucleoporin NUP313, putative (NUP313) Name tag: TurboID-3XHA |
Phenotype |
Asexual bloodstage;
|
RMgm-5241
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1140100; Gene model (P.falciparum): PF3D7_1364200; Gene product: nucleoporin NUP205, putative (NUP205) Name tag: TurboID-3XHA |
Phenotype |
Asexual bloodstage;
|
RMgm-5242
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0416300; Gene model (P.falciparum): PF3D7_0905100; Gene product: nucleoporin NUP221, putative (NUP221) Name tag: TurboID-3XHA |
Phenotype |
Asexual bloodstage;
|
RMgm-5243
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0107600; Gene model (P.falciparum): PF3D7_0609000; Gene product: nucleoporin NUP637, putative (NUP637) Name tag: TurboID-3XHA |
Phenotype |
Asexual bloodstage;
|
RMgm-5244
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0309200; Gene model (P.falciparum): PF3D7_0212400; Gene product: conserved Plasmodium protein, unknown function (NUP390) Name tag: TurboID-3XHA |
Phenotype |
Asexual bloodstage;
|
RMgm-5245
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0309400; Gene model (P.falciparum): PF3D7_0212500; Gene product: conserved Plasmodium protein, unknown function (NUP434) Name tag: GFP |
Phenotype |
Asexual bloodstage;
|
RMgm-5246
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0807900; Gene model (P.falciparum): PF3D7_0317300; Gene product: conserved Plasmodium protein, unknown function (NUP335) Name tag: GFP |
Phenotype |
Asexual bloodstage;
|
RMgm-5247
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1365100; Gene model (P.falciparum): PF3D7_1352400; Gene product: conserved Plasmodium protein, unknown function (NUP176) Name tag: GFP |
Phenotype |
Asexual bloodstage;
|
RMgm-5248
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1454600; Gene model (P.falciparum): PF3D7_1241200; Gene product: conserved Plasmodium protein, unknown function (NUP269) Name tag: GFP |
Phenotype |
Asexual bloodstage;
|
RMgm-5249
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0609700; Gene model (P.falciparum): PF3D7_1211200; Gene product: conserved Plasmodium protein, unknown function Name tag: GFP |
Phenotype |
Asexual bloodstage;
|
RMgm-5250
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0807900; Gene model (P.falciparum): PF3D7_0317300; Gene product: conserved Plasmodium protein, unknown function (NUP335) |
Phenotype | No phenotype has been described |
RMgm-5251
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1365100; Gene model (P.falciparum): PF3D7_1352400; Gene product: conserved Plasmodium protein, unknown function (NUP176) |
Phenotype | No phenotype has been described |
RMgm-5252
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1454600; Gene model (P.falciparum): PF3D7_1241200; Gene product: conserved Plasmodium protein, unknown function (NUP269) |
Phenotype | No phenotype has been described |
RMgm-5253
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0514200; Gene model (P.falciparum): PF3D7_1030200; Gene product: claudin-like apicomplexan microneme protein, putative (CLAMP) Details mutation: a mutated clamp gene with two LoxN sites (up- and downstream of the gene) |
Phenotype | No phenotype has been described |
RMgm-5254
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1015500; Gene model (P.falciparum): PF3D7_1429200; Gene product: AP2 domain transcription factor AP2-O3, putative (ApiAP2; AP2-O3; PbAP2-FG2) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-5255
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1015500; Gene model (P.falciparum): PF3D7_1429200; Gene product: AP2 domain transcription factor AP2-O3, putative (ApiAP2; AP2-O3; PbAP2-FG2) Name tag: GFP |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-5256
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1418100; Gene model (P.falciparum): PF3D7_1319600; Gene product: ACDC domain-containing protein, putative (AP2R-2 (AP2 Transcription Factor-related gene 2)) Name tag: GFP |
Phenotype |
Gametocyte/Gamete;
|
RMgm-5257
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: Exp2, C-terminally tagged with the glucosamine-activated glmS ribozyme, mRuby, GFP and 3xHA |
Phenotype |
Asexual bloodstage;
Liver stage; |
RMgm-5258
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: Exp2, C-terminally tagged with the glucosamine-activated glmS ribozyme, 3xHA and nanoluciferase |
Phenotype |
Liver stage; |