RMgmDB - Rodent Malaria genetically modified Parasites
Search for genetically modified parasite lines by:
Search database by RMgm ID
5534 results for:
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RMgm-4757Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0918700; Gene model (P.falciparum): PF3D7_1131100; Gene product: serpentine receptor, putative (SR1) Phenotype Gametocyte/Gamete;
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RMgm-4758Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1433900; Gene model (P.falciparum): PF3D7_1215900; Gene product: serpentine receptor, putative (SR10) Phenotype Gametocyte/Gamete;
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RMgm-4759Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0524600; Gene model (P.falciparum): PF3D7_0422800; Gene product: serpentine receptor, putative (SR12) Phenotype Gametocyte/Gamete;
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RMgm-4760Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0605800; Gene model (P.falciparum): PF3D7_1204400; Gene product: sexual stage-specific protein G37, putative (G37) Phenotype Gametocyte/Gamete;
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RMgm-4761Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0617400; Gene model (P.falciparum): PF3D7_0717000; Gene product: conserved Plasmodium membrane protein, unknown function Phenotype Gametocyte/Gamete;
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RMgm-4762Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1128600; Gene model (P.falciparum): PF3D7_0628400; Gene product: protease, putative Phenotype Gametocyte/Gamete;
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RMgm-4763Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1313900; Gene model (P.falciparum): PF3D7_1446300; Gene product: conserved Plasmodium membrane protein, unknown function Phenotype Gametocyte/Gamete;
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RMgm-4764Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0702400; Gene model (P.falciparum): PF3D7_0828600; Gene product: folate transporter 1 (FT1) Phenotype Gametocyte/Gamete;
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RMgm-4765Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0933500; Gene model (P.falciparum): PF3D7_1116500; Gene product: folate transporter 2 (FT2) Phenotype Gametocyte/Gamete;
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RMgm-4766Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0309400; Gene model (P.falciparum): PF3D7_0212000; Gene product: GDP-fructose:GMP antiporter, putative Phenotype Gametocyte/Gamete;
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RMgm-4767Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0936300; Gene model (P.falciparum): PF3D7_1113300; Gene product: UDP-galactose transporter, putative (UGT) Phenotype Gametocyte/Gamete;
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RMgm-4768Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1436400; Gene model (P.falciparum): PF3D7_1218400; Gene product: triose or hexose phosphate/phosphate translocator, putative Phenotype Gametocyte/Gamete;
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RMgm-4769Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0823700; Gene model (P.falciparum): PF3D7_0919500; Gene product: major facilitator superfamily domain-containing protein, putative (MFS3) Phenotype Gametocyte/Gamete;
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RMgm-4770Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0820300; Gene model (P.falciparum): PF3D7_0916000; Gene product: major facilitator superfamily domain-containing protein, putative (MFS2) Phenotype Gametocyte/Gamete;
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RMgm-4771Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0917400; Gene model (P.falciparum): PF3D7_1132500; Gene product: amino acid transporter, putative Phenotype Gametocyte/Gamete;
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RMgm-4772Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0609400; Gene model (P.falciparum): PF3D7_1208400; Gene product: amino acid transporter, putative Phenotype Gametocyte/Gamete;
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RMgm-4773Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1446300; Gene model (P.falciparum): PF3D7_1229100; Gene product: multidrug resistance-associated protein 2 (MRP2) Phenotype Gametocyte/Gamete;
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RMgm-4774Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1315500; Gene model (P.falciparum): PF3D7_1447900; Gene product: multidrug resistance protein 2 (MDR2) Phenotype Gametocyte/Gamete;
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RMgm-4775Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0904900; Gene model (P.falciparum): PF3D7_1145500; Gene product: ABC transporter B family member 3, putative (ABCB3) Phenotype Gametocyte/Gamete;
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RMgm-4776Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0403400; Gene model (P.falciparum): PF3D7_0302600; Gene product: ABC transporter B family member 4, putative (ABCB4) Phenotype Gametocyte/Gamete;
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RMgm-4777Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1358700; Gene model (P.falciparum): PF3D7_1339900; Gene product: ABC transporter B family member 5, putative (ABCB5) Phenotype Gametocyte/Gamete;
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RMgm-4778Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0610800; Gene model (P.falciparum): PF3D7_1209900; Gene product: ABC transporter B family member 7, putative (ABCB7) Phenotype Gametocyte/Gamete;
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RMgm-4779Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0928600; Gene model (P.falciparum): PF3D7_1121700; Gene product: protein GCN20 Phenotype Gametocyte/Gamete;
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RMgm-4780Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1019600; Gene model (P.falciparum): PF3D7_1426500; Gene product: ABC transporter G family member 2 (ABCG2) Phenotype Gametocyte/Gamete;
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RMgm-4781Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1031600; Gene model (P.falciparum): PF3D7_1413500; Gene product: iron-sulfur cluster assembly protein SufC (SufC) Phenotype Gametocyte/Gamete;
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RMgm-4782Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0929900; Gene model (P.falciparum): PF3D7_1120300; Gene product: CorA-like Mg2+ transporter protein, putative (MIT1) Phenotype Gametocyte/Gamete;
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RMgm-4783Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1018500; Gene model (P.falciparum): PF3D7_1427600; Gene product: CorA-like Mg2+ transporter protein, putative (MIT3) Phenotype Gametocyte/Gamete;
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RMgm-4784Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0703300; Gene model (P.falciparum): PF3D7_0827700; Gene product: magnesium transporter, putative Phenotype Gametocyte/Gamete;
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RMgm-4785Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1240600; Gene model (P.falciparum): PF3D7_0522600; Gene product: magnesium transporter NIPA, putative Phenotype Gametocyte/Gamete;
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RMgm-4786Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1441100; Gene model (P.falciparum): PF3D7_1223700; Gene product: vacuolar iron transporter (VIT) Phenotype Gametocyte/Gamete;
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RMgm-4787Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1367300; Gene model (P.falciparum): PF3D7_1348800; Gene product: E1-E2 ATPase, putative Phenotype Gametocyte/Gamete;
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RMgm-4788Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1424200; Gene model (P.falciparum): PF3D7_0715900; Gene product: cation diffusion facilitator family protein, putative Phenotype Gametocyte/Gamete;
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RMgm-4789Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1105200; Gene model (P.falciparum): PF3D7_0504500; Gene product: MOLO1 domain-containing protein, putative Phenotype Gametocyte/Gamete;
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RMgm-4790Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1315200; Gene model (P.falciparum): PF3D7_1447600; Gene product: conserved protein, unknown function Phenotype Gametocyte/Gamete;
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RMgm-4791Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1339400; Gene model (P.falciparum): PF3D7_1471500; Gene product: transmembrane protein 43, putative (TMEM43) Phenotype Gametocyte/Gamete;
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RMgm-4792Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1342800; Gene model (P.falciparum): PF3D7_1322900; Gene product: conserved protein, unknown function Phenotype Gametocyte/Gamete;
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RMgm-4793Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1366100; Gene model (P.falciparum): PF3D7_1347600; Gene product: conserved protein, unknown function Phenotype Gametocyte/Gamete;
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RMgm-4794Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1463300; Gene model (P.falciparum): PF3D7_1247800; Gene product: dipeptidyl aminopeptidase 2 (DPAP2) Phenotype Gametocyte/Gamete;
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RMgm-4795Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta) Phenotype Gametocyte/Gamete;
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RMgm-4796Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0619700; Gene model (P.falciparum): PF3D7_0719500; Gene product: LEM3/CDC50 family protein, putative (CDC50A) Phenotype Gametocyte/Gamete;
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RMgm-4797Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0916600; Gene model (P.falciparum): PF3D7_1133300; Gene product: LEM3/CDC50 family protein, putative (CDC50B) Phenotype Gametocyte/Gamete;
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RMgm-4798Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0809500; Gene model (P.falciparum): PF3D7_0319000; Gene product: P-type ATPase, putative (ATPase7) Phenotype Gametocyte/Gamete;
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RMgm-4799Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1421700; Gene model (P.falciparum): PF3D7_0713400; Gene product: GPCR-like receptor SR25 (SR25) Phenotype No phenotype has been described
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RMgm-4800Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_0914700; Gene model (P.falciparum): PF3D7_1135300; Gene product: conserved Plasmodium membrane protein, unknown function Phenotype No phenotype has been described
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RMgm-4801Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_0307300; Gene model (P.falciparum): PF3D7_0209600; Gene product: transporter, putative Phenotype No phenotype has been described
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RMgm-4802Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1448600; Gene model (P.falciparum): PF3D7_1231400; Gene product: amino acid transporter, putative Phenotype No phenotype has been described
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RMgm-4803Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1241000; Gene model (P.falciparum): PF3D7_0523000; Gene product: multidrug resistance protein 1 Phenotype No phenotype has been described
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RMgm-4804Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1370600; Gene model (P.falciparum): PF3D7_1352100; Gene product: ABC transporter B family member 6, putative (ABCB6) Phenotype No phenotype has been described
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RMgm-4805Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1145400; Gene model (P.falciparum): PF3D7_1368200; Gene product: ABC transporter E family member 1, putative (ABCE1) Phenotype No phenotype has been described
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RMgm-4806Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1425800; Gene model (P.falciparum): PF3D7_0813700; Gene product: ABC transporter F family member 1 (ABCF1) Phenotype No phenotype has been described
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RMgm-4807Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1222000; Gene model (P.falciparum): PF3D7_0319700; Gene product: ABC transporter I family member 1, putative (ABCI3) Phenotype No phenotype has been described
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RMgm-4808Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_0407300; Gene model (P.falciparum): PF3D7_0306700; Gene product: ER membrane protein complex subunit 5, putative (EMC5) Phenotype No phenotype has been described
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RMgm-4809Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_0109300; Gene model (P.falciparum): PF3D7_0609100; Gene product: zinc transporter ZIP1, putative (ZIP1) Phenotype No phenotype has been described
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RMgm-4810Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_0911700; Gene model (P.falciparum): PF3D7_1138400; Gene product: guanylyl cyclase alpha (GCalpha) Phenotype No phenotype has been described
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RMgm-4811Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1437200; Gene model (P.falciparum): PF3D7_1219600; Gene product: aminophospholipid-transporting P-ATPase (ATPase2) Phenotype No phenotype has been described
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RMgm-4812Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_1440800; Gene model (P.falciparum): PF3D7_1223400; Gene product: phospholipid-transporting ATPase, putative Phenotype No phenotype has been described
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RMgm-4813Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1116300; Gene model (P.falciparum): PF3D7_0515500; Gene product: gametogenesis essential protein 1, putative (GEP1) Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-4814Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1115100; Gene model (P.falciparum): PF3D7_0515500; Gene product: gametogenesis essential protein 1, putative (GEP1) Phenotype Gametocyte/Gamete;
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RMgm-4815Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0933700; Gene model (P.falciparum): PF3D7_1113900; Gene product: mitogen-activated protein kinase 2 (MAP2) Phenotype Gametocyte/Gamete;
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RMgm-4816Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0935700; Gene model (P.falciparum): PF3D7_1113900; Gene product: mitogen-activated protein kinase 2 (MAP2) Phenotype Gametocyte/Gamete;
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RMgm-4817Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0619400; Gene model (P.falciparum): PF3D7_0719200; Gene product: NIMA related kinase 4 (NEK4) Phenotype Gametocyte/Gamete;
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RMgm-4818Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0617900; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Phenotype Gametocyte/Gamete;
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RMgm-4819Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1116300; Gene model (P.falciparum): PF3D7_0515500; Gene product: gametogenesis essential protein 1, putative (GEP1)
Name tag: 6xHA
Phenotype Gametocyte/Gamete; Fertilization and ookinete;
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RMgm-4820Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1116300; Gene model (P.falciparum): PF3D7_0515500; Gene product: gametogenesis essential protein 1, putative (GEP1)
Name tag: 4xMyc
Phenotype Gametocyte/Gamete; Fertilization and ookinete;
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RMgm-4821Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0526200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein (SEP1)
Name tag: 4xMyc
Phenotype Gametocyte/Gamete;
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RMgm-4822Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0911700; Gene model (P.falciparum): PF3D7_1138400; Gene product: guanylyl cyclase (GCalpha, GCα)
Name tag: 4xMyc
Phenotype Gametocyte/Gamete;
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RMgm-4823Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0112100; Gene model (P.falciparum): PF3D7_0613800; Gene product: AP2 domain transcription factor, putative
Details mutation: T-to-C transition at position 5468 (serine (S) into phenylalanine (F))
Phenotype Asexual bloodstage;
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RMgm-4824Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1119200; Gene model (P.falciparum): PF3D7_0620000; Gene product: PIMMS43 protein (secreted ookinete protein 25 (PSOP25), ookinete surface-associated protein 8 (POS8)) Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Oocyst; Sporozoite;
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RMgm-4825Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1119200; Gene model (P.falciparum): PF3D7_0620000; Gene product: PIMMS43 protein (secreted ookinete protein 25 (PSOP25), ookinete surface-associated protein 8 (POS8)) Transgene Transgene not Plasmodium: mCherry
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Oocyst; Sporozoite;
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RMgm-4826Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1119200; Gene model (P.falciparum): PF3D7_0620000; Gene product: PIMMS43 protein (secreted ookinete protein 25 (PSOP25), ookinete surface-associated protein 8 (POS8))
Details mutation: P. berghei pimms43 gene replaced by the pimms43 gene of P. falciparum
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Gametocyte/Gamete; Fertilization and ookinete; Sporozoite;
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RMgm-4827Malaria parasite P. yoelii Genotype Transgene Transgene not Plasmodium: Ovalbumin::mCherry
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage;
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RMgm-4828Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0208800; Gene model (P.falciparum): PF3D7_0104300; Gene product: ubiquitin carboxyl-terminal hydrolase 1, putative (UBP1)
Details mutation: UBP1 mutated - V2721F
Phenotype Asexual bloodstage;
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RMgm-4829Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0208800; Gene model (P.falciparum): PF3D7_0104300; Gene product: ubiquitin carboxyl-terminal hydrolase 1, putative (UBP1)
Details mutation: UBP1 mutated - V2752F
Phenotype Asexual bloodstage;
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RMgm-4830Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1115200; Gene model (P.falciparum): PF3D7_0515600; Gene product: gamete egress protein GEP, putative (GEP) Transgene Transgene not Plasmodium: GFP
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (GEP)
3'UTR: Gene model: Not available; Gene product: Not available
Replacement locus: Gene model: PBANKA_1115200; Gene product: gamete egress protein GEP, putative (GEP)
Phenotype Gametocyte/Gamete;
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RMgm-4831Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0712900; Gene model (P.falciparum): PF3D7_0817900; Gene product: high mobility group protein B2 (HMGB2) Phenotype Asexual bloodstage;
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RMgm-4832Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0414500; Gene model (P.falciparum): PF3D7_0316700; Gene product: protein YOP1, putative (YOP1) Phenotype Asexual bloodstage; Oocyst; Sporozoite; Liver stage;
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RMgm-4833Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1018100; Gene model (P.falciparum): PF3D7_1426500; Gene product: ABC transporter G family member 2 (ABCG2)
Name tag: mCherry
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete;
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RMgm-4834Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0608000; Gene model (P.falciparum): PF3D7_1209600; Gene product: porphobilinogen deaminase (PBGD) Phenotype No phenotype has been described
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RMgm-4835Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1018100; Gene model (P.falciparum): PF3D7_1426500; Gene product: ABC transporter G family member 2 (ABCG2) Phenotype Gametocyte/Gamete;
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RMgm-4836Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1018100; Gene model (P.falciparum): PF3D7_1426500; Gene product: ABC transporter G family member 2 (ABCG2)
Details mutation: The abcg2 gene of P. berghei replaced by the P. falciparum abcg2 gene
Phenotype Gametocyte/Gamete;
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RMgm-4837Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1418900; Gene model (P.falciparum): PF3D7_1320600; Gene product: ras-related protein Rab-11A (RAB11a)
Details mutation: 'promoter-swap' mutant; the rab11a promoter replaced by the promoter of PBANKA_1400600 (clag)
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (eef1a)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-4838Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1433900; Gene model (P.falciparum): PF3D7_1215900; Gene product: serpentine receptor 10, putative (SR10) Phenotype Asexual bloodstage;
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RMgm-4839Malaria parasite P. chabaudi Genotype Disrupted Gene model (rodent): PCHAS_1433600; Gene model (P.falciparum): PF3D7_1215900; Gene product: serpentine receptor 10, putative (SR10) Phenotype Asexual bloodstage;
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RMgm-4840Malaria parasite P. chabaudi Genotype Transgene Transgene not Plasmodium: GFP
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS)
Replacement locus: Gene model: PCHAS_0308200; Gene product: 6-cysteine protein P230p, putative (P230p)
Phenotype Asexual bloodstage; Gametocyte/Gamete; Oocyst; Sporozoite;
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RMgm-4841Malaria parasite P. chabaudi Genotype Transgene Transgene not Plasmodium: mCherry
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS)
Replacement locus: Gene model: PCHAS_0308200; Gene product: 6-cysteine protein P230p, putative (P230p)
Phenotype No phenotype has been described
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RMgm-4842Malaria parasite P. chabaudi Genotype Disrupted Gene model (rodent): PCHAS_1304000; Gene model (P.falciparum): PF3D7_1475400; Gene product: cysteine repeat modular protein 4 (CRMP4) Transgene Transgene not Plasmodium: GFP
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS)
Replacement locus: Gene model: PCHAS_0308200; Gene product: 6-cysteine protein P230p, putative (P230p)
Phenotype Asexual bloodstage;
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RMgm-4843Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1115700; Gene model (P.falciparum): PF3D7_0616200; Gene product: kinetochore protein NDC80, putative (NDC80)
Name tag: GFP
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-4844Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1115700; Gene model (P.falciparum): PF3D7_0616200; Gene product: kinetochore protein NDC80, putative (NDC80)
Name tag: mCherry
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-4845Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1230200; Gene model (P.falciparum): PF3D7_0615500; Gene product: cdc2-related protein kinase 5 (CRK5) Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
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RMgm-4846Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0824400; Gene model (P.falciparum): PF3D7_0923500; Gene product: cyclin-dependent kinases regulatory subunit, putative (CDKrs) Phenotype Gametocyte/Gamete;
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RMgm-4847Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1230200; Gene model (P.falciparum): PF3D7_0615500; Gene product: cdc2-related protein kinase 5 (CRK5)
Name tag: GFP
Phenotype Gametocyte/Gamete; Oocyst;
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RMgm-4848Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1230200; Gene model (P.falciparum): PF3D7_0615500; Gene product: cdc2-related protein kinase 5 (CRK5)
Name tag: triple-HA
Phenotype Gametocyte/Gamete;
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RMgm-4849Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0824400; Gene model (P.falciparum): PF3D7_0923500; Gene product: cyclin-dependent kinases regulatory subunit, putative (CDKrs)
Name tag: GFP
Phenotype Gametocyte/Gamete;
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RMgm-4850Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0824400; Gene model (P.falciparum): PF3D7_0923500; Gene product: cyclin-dependent kinases regulatory subunit, putative (CDKrs)
Name tag: triple-HA
Phenotype Gametocyte/Gamete;
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RMgm-4851Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP)
Details mutation: The endogenous P. berghei csp gene replaced by the P. falciparum csp gene
Phenotype No phenotype has been described
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RMgm-4852Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0826700; Gene model (P.falciparum): PF3D7_0925900; Gene product: lipocalin (LCN, parasitophorous vacuole protein 5, PV5)
Details mutation: 'promoter-swap' mutant; the PbPV5 promoter replaced by the promoter of PBANKA_0941300 (PbTEX88)
Transgene Transgene not Plasmodium: GFP
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS)
Replacement locus: Gene model: Not available; Gene product: Not available
Phenotype Asexual bloodstage;
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RMgm-4853Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0826700; Gene model (P.falciparum): PF3D7_0925900; Gene product: lipocalin (LCN, parasitophorous vacuole protein 5, PV5)
Details mutation: 'promoter-swap' mutant; the PbPV5 promoter replaced by the promoter of PBANKA_0931200 (PbHSP101)
Transgene Transgene not Plasmodium: GFP
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS)
Replacement locus: Gene model: Not available; Gene product: Not available
Phenotype Asexual bloodstage;
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RMgm-4854Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PYYM_0017400; Gene model (P.falciparum): Not available; Gene product: PIR protein (YIR)
Name tag: GFP
Phenotype Asexual bloodstage;
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RMgm-4855Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1455400; Gene model (P.falciparum): PF3D7_1242000; Gene product: sulfhydryl oxidase, putative (Quiescin sulfhydryl oxidase, QSOX) Phenotype Fertilization and ookinete; Oocyst;
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RMgm-4856Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0112100; Gene model (P.falciparum): PF3D7_0613800; Gene product: AP2 domain transcription factor, putative (ApiAP2)
Details mutation: A phenylalanine 1823 is replaced with with serine (F1823S)
Phenotype Asexual bloodstage;