RMgmDB - Rodent Malaria genetically modified Parasites
Search for genetically modified parasite lines by:
Search database by RMgm ID
5534 results for:
-
RMgm-4657Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0921600; Gene model (P.falciparum): PF3D7_1126800; Gene product: RNA-binding protein, putative (PbSR-MG) Phenotype Gametocyte/Gamete; Oocyst;
-
RMgm-4658Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0921600; Gene model (P.falciparum): PF3D7_1126800; Gene product: RNA-binding protein, putative (PbSR-MG)
Name tag: triple-HA
Phenotype Asexual bloodstage; Gametocyte/Gamete;
-
RMgm-4659Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1103300; Gene model (P.falciparum): PF3D7_0503600; Gene product: myosin B (MyoB) Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4660Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1444500; Gene model (P.falciparum): PF3D7_1229800; Gene product: myosin J (MyoJ) Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4661Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0112200; Gene model (P.falciparum): PF3D7_0613900; Gene product: myosin E (MyoE) Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Sporozoite;
-
RMgm-4662Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1344100; Gene model (P.falciparum): PF3D7_1329100; Gene product: myosin F (MyoF) Phenotype No phenotype has been described
-
RMgm-4663Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_0908500; Gene model (P.falciparum): PF3D7_1140500; Gene product: myosin K (MyoK) Phenotype No phenotype has been described
-
RMgm-4664Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1444500; Gene model (P.falciparum): PF3D7_1229800; Gene product: myosin J (MyoJ)
Name tag: GFP
Phenotype Oocyst;
-
RMgm-4665Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0112200; Gene model (P.falciparum): PF3D7_0613900; Gene product: myosin E (MyoE)
Name tag: GFP
Phenotype Asexual bloodstage; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4666Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1344100; Gene model (P.falciparum): PF3D7_1329100; Gene product: myosin F (MyoF)
Name tag: GFP
Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
-
RMgm-4667Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0908500; Gene model (P.falciparum): PF3D7_1140500; Gene product: myosin K (MyoK)
Name tag: GFP
Phenotype Gametocyte/Gamete; Fertilization and ookinete;
-
RMgm-4668Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0929400; Gene model (P.falciparum): PF3D7_1118700; Gene product: myosin light chain B (MCL-B)
Name tag: GFP
Phenotype Fertilization and ookinete;
-
RMgm-4669Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1355700; Gene model (P.falciparum): PF3D7_1342600; Gene product: myosin A (MyoA)
Name tag: mCherry
Phenotype Asexual bloodstage; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4670Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0939100; Gene model (P.falciparum): PF3D7_1107800; Gene product: AP2 domain transcription factor, putative (ApiAP2)
Name tag: triple-HA
Phenotype Asexual bloodstage;
-
RMgm-4671Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0942700; Gene model (P.falciparum): PF3D7_1104200; Gene product: chromatin remodeling protein (SNF2L)
Name tag: triple-HA
Phenotype Asexual bloodstage;
-
RMgm-4672Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0716000; Gene model (P.falciparum): PF3D7_0414000; Gene product: structural maintenance of chromosomes protein 3, putative (SMC3)
Name tag: triple-HA
Phenotype Asexual bloodstage;
-
RMgm-4673Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0202700; Gene model (P.falciparum): PF3D7_0111000; Gene product: kinesin-8, putative (kinesin-8b) Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst;
-
RMgm-4674Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0202700; Gene model (P.falciparum): PF3D7_0111000; Gene product: kinesin-8, putative (kinesin-8b)
Name tag: GFP
Phenotype Gametocyte/Gamete;
-
RMgm-4675Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1436600; Gene model (P.falciparum): PF3D7_1221400; Gene product: inner membrane complex protein 1h, putative (IMC1h)
Details mutation: Deletion of domain 1 (“alveolin” module) of IMC1h (amino acids amino acids 397 to 504)
Phenotype Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4676Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1436600; Gene model (P.falciparum): PF3D7_1221400; Gene product: inner membrane complex protein 1h, putative (IMC1h)
Details mutation: Deletion of domain 2 (arboxy-terminalmodule) of IMC1h is deleted (amino acids 397 to 504)
Phenotype Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4677Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0311400; Gene model (P.falciparum): PF3D7_0214600; Gene product: serine/threonine protein kinase, putative (stk2) Transgene Transgene not Plasmodium: GFP
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70)
Replacement locus: Gene model: PBANKA_0311400; Gene product: serine/threonine protein kinase, putative (stk2)
Phenotype Sporozoite; Liver stage;
-
RMgm-4678Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0810400; Gene model (P.falciparum): PF3D7_0909200; Gene product: GDP-fucose protein O-fucosyltransferase 2 (PoFUT2) Phenotype No phenotype has been described
-
RMgm-4679Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1400800; Gene model (P.falciparum): PF3D7_1302200; Gene product: early transcribed membrane protein 13 (UIS3; up-regulated in infective sporozoites; ETRAMP13) Transgene Transgene not Plasmodium: Melanoma-associated antigen 3 (MAGE-A3)
Promoter: Gene model: PBANKA_1400800; Gene model (P.falciparum): PF3D7_1302200; Gene product: early transcribed membrane protein 13 (UIS3; up-regulated in infective sporozoites; ETRAMP13)
3'UTR: Gene model: PBANKA_1400800; Gene product: early transcribed membrane protein 13 (UIS3; up-regulated in infective sporozoites; ETRAMP13)
Replacement locus: Gene model: PBANKA_1400800; Gene product: early transcribed membrane protein 13 (UIS3; up-regulated in infective sporozoites; ETRAMP13)
Phenotype Sporozoite; Liver stage;
-
RMgm-4680Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Sporozoite;
-
RMgm-4681Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CS; CSP) Transgene Transgene not Plasmodium: mCherry
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene not Plasmodium: Luciferase
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Oocyst; Sporozoite;
-
RMgm-4682Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0202700; Gene model (P.falciparum): PF3D7_0111000; Gene product: kinesin-8B, putative Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4683Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0202700; Gene model (P.falciparum): PF3D7_0111000; Gene product: kinesin-8B, putative
Name tag: GFP
Phenotype Gametocyte/Gamete;
-
RMgm-4684Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0805900; Gene model (P.falciparum): PF3D7_0319400; Gene product: kinesin-8, putative (kinesin-8X) Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Oocyst; Sporozoite; Liver stage;
-
RMgm-4685Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0805900; Gene model (P.falciparum): PF3D7_0319400; Gene product: kinesin-8, putative (kinesin-8X)
Name tag: GFP
Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4686Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0931000; Gene model (P.falciparum): PF3D7_1117000; Gene product: conserved Plasmodium membrane protein, unknown function (Pb115) Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst;
-
RMgm-4687Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0931000; Gene model (P.falciparum): PF3D7_1117000; Gene product: conserved Plasmodium membrane protein, unknown function (Pb115)
Name tag: triple-HA
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete;
-
RMgm-4688Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0407300; Gene model (P.falciparum): PF3D7_0309100; Gene product: OMD protein, putative (ookinete motility deficient, OMD) Phenotype Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4689Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0407300; Gene model (P.falciparum): PF3D7_0309100; Gene product: OMD protein, putative (ookinete motility deficient, OMD)
Name tag: GFP
Phenotype Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;
-
RMgm-4690Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1315700; Gene model (P.falciparum): PF3D7_1452000; Gene product: rhoptry neck protein 2 (RON2)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4691Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4692Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0713100; Gene model (P.falciparum): PF3D7_0817700; Gene product: rhoptry neck protein 5 (RON5)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4693Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0311700; Gene model (P.falciparum): PF3D7_0214900; Gene product: rhoptry neck protein 6 (RON6)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4694Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1464900; Gene model (P.falciparum): PF3D7_1252100; Gene product: rhoptry neck protein 3 (RON3)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4695Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0619700; Gene model (P.falciparum): PF3D7_0722200; Gene product: rhoptry-associated leucine zipper-like protein 1 (RALP1)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4696Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1032100; Gene model (P.falciparum): PF3D7_1410400; Gene product: rhoptry-associated protein 1 (RAP1)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4697Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1400600; Gene model (P.falciparum): PF3D7_0220800; Gene product: cytoadherence linked asexual protein 2 (CLAG2, RhopH1A)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4698Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0830200; Gene model (P.falciparum): PF3D7_0929400; Gene product: high molecular weight rhoptry protein 2 (RhopH2)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4699Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0416000; Gene model (P.falciparum): PF3D7_0905400; Gene product: high molecular weight rhoptry protein 3 (RhopH3)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Sporozoite;
-
RMgm-4700Malaria parasite P. berghei Genotype Transgene Transgene Plasmodium: Gene model: PF3D7_1036400; Gene model (P.falciparum): PF3D7_1036400; Gene product: liver stage antigen 1 (LSA1)
Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene not Plasmodium: GFP-Luciferase
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene Plasmodium: Gene model: PF3D7_0202100; Gene model (P.falciparum): PF3D7_0202100; Gene product: liver stage associated protein 2 | Plasmodium exported protein (PHISTc), unknown function (LSAP2)
Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (S1)
Phenotype Sporozoite; Liver stage;
-
RMgm-4701Malaria parasite P. berghei Genotype Transgene Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2)
Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene not Plasmodium: GFP-Luciferase
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene Plasmodium: Gene model: PF3D7_0202100; Gene model (P.falciparum): PF3D7_0202100; Gene product: liver stage associated protein 2 | Plasmodium exported protein (PHISTc), unknown function (LSAP2)
Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (S1)
Phenotype Sporozoite; Liver stage;
-
RMgm-4702Malaria parasite P. berghei Genotype Transgene Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2)
Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene not Plasmodium: GFP-Luciferase
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene Plasmodium: Gene model: PF3D7_1036400; Gene model (P.falciparum): PF3D7_1036400; Gene product: liver stage antigen 1 (LSA1)
Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4)
Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (S1)
Phenotype Sporozoite; Liver stage;
-
RMgm-4703Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0309500; Gene model (P.falciparum): PF3D7_0212600; Gene product: secreted protein with altered thrombospondin repeat domain (SPATR)
Details mutation: The mutant contains a FRTed (part of the) ORF of the spatr locus
Details conditional mutagenesis: (Part of) the ORF of spatr is removed in the sporozoite stage by the Flp/FRT system
Transgene Transgene not Plasmodium: FlpL recombinase of yeast (FlpL)
Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2)
3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Liver stage;
-
RMgm-4704Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_0309500; Gene model (P.falciparum): PF3D7_0212600; Gene product: secreted protein with altered thrombospondin repeat domain (SPATR) Phenotype No phenotype has been described
-
RMgm-4705Malaria parasite P. yoelii Genotype Mutated Gene model (rodent): PY17X_1337400; Gene model (P.falciparum): PF3D7_1301600; Gene product: erythrocyte binding antigen-140 (EBL; erythrocyte binding antigen-140; EBA140; BAEBL, EBP2)
Details mutation: Tyr-to-Cys substitution at residue 741 (Y741 to C741) in the C-Cys domain of PyEBL of Py-N67
Phenotype Asexual bloodstage;
-
RMgm-4706Malaria parasite P. yoelii Genotype Mutated Gene model (rodent): PY17X_1337400; Gene model (P.falciparum): PF3D7_1301600; Gene product: erythrocyte binding antigen-140 (EBL; erythrocyte binding antigen-140; EBA140; BAEBL, EBP2)
Details mutation: Cys-to-Tyr substitution at residue 741 (C741 to Y741) in the C-Cys domain of PyEBL of Py-N67C
Phenotype Asexual bloodstage;
-
RMgm-4707Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1205000; Gene model (P.falciparum): PF3D7_1006800; Gene product: single-strand telomeric DNA-binding protein GBP2, putative (GBP2, G-strand binding protein 2) Phenotype Asexual bloodstage; Gametocyte/Gamete;
-
RMgm-4708Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1220300; Gene model (P.falciparum): PF3D7_0321400; Gene product: protein kinase, putative (pPK1, pseudokinase) Phenotype Asexual bloodstage; Gametocyte/Gamete; Oocyst;
-
RMgm-4709Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1220300; Gene model (P.falciparum): PF3D7_0321400; Gene product: protein kinase, putative (pPK1, pseudokinase)
Name tag: c-myc
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete;
-
RMgm-4710Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0820300; Gene model (P.falciparum): PF3D7_0919400; Gene product: protein disulfide isomerase (PDI9; PDI-Trans) Phenotype Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4711Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0820300; Gene model (P.falciparum): PF3D7_0919400; Gene product: protein disulfide isomerase (PDI9; PDI-Trans)
Name tag: EGFP
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Sporozoite;
-
RMgm-4712Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1315700; Gene model (P.falciparum): PF3D7_1452000; Gene product: rhoptry neck protein 2 (RON2)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4713Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4714Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0713100; Gene model (P.falciparum): PF3D7_0817700; Gene product: rhoptry neck protein 5 (RON5)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4715Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0311700; Gene model (P.falciparum): PF3D7_0214900; Gene product: rhoptry neck protein 6 (RON6)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4716Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1464900; Gene model (P.falciparum): PF3D7_1252100; Gene product: rhoptry neck protein 3 (RON3)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4717Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0619700; Gene model (P.falciparum): PF3D7_0722200; Gene product: rhoptry-associated leucine zipper-like protein 1 (RALP1)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4718Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1032100; Gene model (P.falciparum): PF3D7_1410400; Gene product: rhoptry-associated protein 1 (RAP1)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4719Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1400600; Gene model (P.falciparum): PF3D7_0220800; Gene product: cytoadherence linked asexual protein 2 (CLAG2, RhopH1(2), rhoph1a)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4720Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0830200; Gene model (P.falciparum): PF3D7_0929400; Gene product: high molecular weight rhoptry protein 2 (RhopH2)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4721Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0416000; Gene model (P.falciparum): PF3D7_0905400; Gene product: high molecular weight rhoptry protein 3 (RhopH3)
Name tag: c-myc
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4722Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): py17X_1354300; Gene model (P.falciparum): Not available; Gene product: conserved Plasmodium protein, unknown function
Name tag: GFP
Phenotype Sporozoite;
-
RMgm-4723Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0507300; Gene model (P.falciparum): PF3D7_1022000; Gene product: RNA-binding protein, putative (UIS12)
Name tag: GFP
Phenotype Sporozoite; Liver stage;
-
RMgm-4724Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP)
Details mutation: P. berghei csp replaced with P. falciparum (3D7 strain) csp gene
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4725Malaria parasite P. berghei Genotype Transgene Transgene not Plasmodium: Argonaute 2 (Argo2)
Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70)
3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS)
Replacement locus: Gene model: Not available; Gene product: Not available
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Oocyst; Sporozoite;
-
RMgm-4726Malaria parasite P. berghei Genotype Transgene Transgene not Plasmodium: Argonaute 2 (Argo2)
Promoter: Gene model: PBANKA_1003000; Gene model (P.falciparum): PF3D7_0405300; Gene product: liver specific protein 2 (LISP2, putative | sequestrin | 6-cysteine protein)
3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS)
Replacement locus: Gene model: Not available; Gene product: Not available
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Liver stage;
-
RMgm-4727Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1317200; Gene model (P.falciparum): PF3D7_1453500; Gene product: NAD(P) transhydrogenase, putative (NTH) Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
-
RMgm-4728Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1317200; Gene model (P.falciparum): PF3D7_1453500; Gene product: NAD(P) transhydrogenase, putative (NTH)
Name tag: GFP
Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
-
RMgm-4729Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1317200; Gene model (P.falciparum): PF3D7_1453500; Gene product: NAD(P) transhydrogenase, putative (NTH)
Details mutation: N-terminally truncation of NTH (60 amino acids removed downstream of the ER signal peptide)
Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
-
RMgm-4730Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1317200; Gene model (P.falciparum): PF3D7_1453500; Gene product: NAD(P) transhydrogenase, putative (NTH)
Details mutation: the highly conserved aspartic acid residue at position 500 mutated to a lysine
Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
-
RMgm-4731Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1454900; Gene model (P.falciparum): PF3D7_1241500; Gene product: conserved Plasmodium protein, unknown function (UIS8) Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4732Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1454900; Gene model (P.falciparum): PF3D7_1241500; Gene product: conserved Plasmodium protein, unknown function (UIS8)
Details mutation: The uis8 gene of P. berghei replaced with the uis8 gene of P. falciparum
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4733Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0413800; Gene model (P.falciparum): PF3D7_0316000; Gene product: microneme associated antigen (MA) Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4734Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0413800; Gene model (P.falciparum): PF3D7_0316000; Gene product: microneme associated antigen (MA)
Details mutation: The ma gene of P. berghei replaced with the ma gene of P. falciparum
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4735Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1400800; Gene model (P.falciparum): PF3D7_1302200; Gene product: protein UIS3 (ETRAMP13) Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4736Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1400800; Gene model (P.falciparum): PF3D7_1302200; Gene product: protein UIS3 (ETRAMP13)
Details mutation: the P. berghei uis3 gene is replaced with the uis3 gene of P. falciparum
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Liver stage;
-
RMgm-4737Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0410900; Gene model (P.falciparum): PF3D7_0313200; Gene product: conserved protein, unknown function
Details mutation: the P. berghei PBANKA_0410900 gene is replaced with the ortholog of P. falciparum PF3D7_0313200
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Liver stage;
-
RMgm-4738Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_0410900; Gene model (P.falciparum): PF3D7_0313200; Gene product: conserved protein, unknown function Phenotype No phenotype has been described
-
RMgm-4739Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1031000; Gene model (P.falciparum): PF3D7_1411500; Gene product: conserved Plasmodium protein, unknown function Phenotype No phenotype has been described
-
RMgm-4740Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1031000; Gene model (P.falciparum): PF3D7_1411500; Gene product: conserved protein, unknown function
Details mutation: the P. berghei PBANKA_1031000 gene is replaced with the ortholog of P. falciparum PF3D7_1411500
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4741Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0605900; Gene model (P.falciparum): PF3D7_1207400; Gene product: conserved Plasmodium protein, unknown function Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4742Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0605900; Gene model (P.falciparum): PF3D7_1207400; Gene product: conserved Plasmodium protein, unknown function
Details mutation: The PBANKA_0605900 gene of P. berghei replaced with the ortholog of P. falciparum (PF3D7_1207400)
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Sporozoite; Liver stage;
-
RMgm-4743Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1002100; Gene model (P.falciparum): PF3D7_0404400; Gene product: 6-cysteine protein P36 (P36) Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype No phenotype has been described
-
RMgm-4744Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1002100; Gene model (P.falciparum): PF3D7_0404400; Gene product: 6-cysteine protein P36 (P36)
Details mutation: The P36 gene of P. berghei replaced with the P36 ortholog of P. falciparum
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Liver stage;
-
RMgm-4745Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0831000; Gene model (P.falciparum): PF3D7_0930300; Gene product: merozoite surface protein 1 (MSP1)
Details mutation: the last 330 bp of P. berghei msp1 replaced by the last 318 bp of P. vivax msp1
Phenotype No phenotype has been described
-
RMgm-4746Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0833000; Gene model (P.falciparum): PF3D7_0932200; Gene product: profilin (PFN, PRF)
Details mutation: P. berghei profilin replaced by different chimeric forms of profilin
Phenotype Asexual bloodstage; Sporozoite; Liver stage;
-
RMgm-4747Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1416900; Gene model (P.falciparum): PF3D7_1318400; Gene product: structural maintenance of chromosomes protein 2, putative (SMC2)
Name tag: GFP
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4748Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1108700; Gene model (P.falciparum): PF3D7_0509100; Gene product: structural maintenance of chromosomes protein 4, putative (SMC4)
Name tag: GFP
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4749Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1416900; Gene model (P.falciparum): PF3D7_1318400; Gene product: structural maintenance of chromosomes protein 2, putative (SMC2)
Name tag: mCherry
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4750Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1416900; Gene model (P.falciparum): PF3D7_1318400; Gene product: structural maintenance of chromosomes protein 2, putative (SMC2)
Name tag: mCherry
Tagged Gene model (rodent): PBANKA_1108700; Gene model (P.falciparum): PF3D7_0509100; Gene product: structural maintenance of chromosomes protein 4, putative (SMC4)
Name tag: GFP
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4751Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1416900; Gene model (P.falciparum): PF3D7_1318400; Gene product: structural maintenance of chromosomes protein 2, putative (SMC2) Phenotype No phenotype has been described
-
RMgm-4752Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1108700; Gene model (P.falciparum): PF3D7_0509100; Gene product: structural maintenance of chromosomes protein 4, putative (SMC4) Phenotype No phenotype has been described
-
RMgm-4753Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1416900; Gene model (P.falciparum): PF3D7_1318400; Gene product: structural maintenance of chromosomes protein 2, putative (SMC2)
Details mutation: 'promoter swap mutant': the promoter of smc2 replaced with the ama1 promoter (PBANKA_0915000).
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4754Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_1108700; Gene model (P.falciparum): PF3D7_0509100; Gene product: structural maintenance of chromosomes protein 4, putative (SMC4)
Details mutation: 'promoter swap mutant': the promoter of smc4 replaced with the ama1 promoter (PBANKA_0915000).
Transgene Transgene not Plasmodium: GFP (gfp-mu3)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
-
RMgm-4755Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1243400; Gene model (P.falciparum): PF3D7_0525400; Gene product: 7-helix-1 protein Phenotype Gametocyte/Gamete;
-
RMgm-4756Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1431500; Gene model (P.falciparum): PF3D7_1213500; Gene product: integral membrane protein GPR180, putative Phenotype Gametocyte/Gamete;