Search database by RMgm ID
RMgm-47
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-48
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation of the A-domain |
Phenotype |
Sporozoite; Liver stage; |
RMgm-49
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation of the A-domain |
Phenotype |
Sporozoite; Liver stage; |
RMgm-50
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation of the TSR-domain (the distal tryptophan in the WSXW sequence was substituted by alanine) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-51
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation of the TSR-domain (basic residues in the C-terminal cluster changed to alanine residues). |
Phenotype |
Sporozoite; Liver stage; |
RMgm-52
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutations in both the A- and TSR-domain |
Phenotype |
Sporozoite; Liver stage; |
RMgm-53
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1354800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-54
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation in the cytoplasmic tail (abrogation of the tyrosine motif) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-55
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation in the cytoplasmic tail (lacking the 14 carboxy-terminal residues) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-56
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: Mutation in the cytoplasmic tail (lacking the 37 carboxy-terminal residues) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-57
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The cytoplasmic tail domain (CTD) of TRAP replaced with the CTD of T. gondii MIC2 |
Phenotype | No phenotype has been described |
RMgm-58
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The endogenous P. berghei gene replaced with the ortholog of P. falciparum |
Phenotype |
Sporozoite; Liver stage; |
RMgm-149
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The cytoplasmic tail domain (CTD) of TRAP replaced with the CTD of TLP (Trap-Like Protein (AY484471) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-150
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The cytoplasmic tail domain (CTD) of TRAP replaced with the CTD of CTRP (CSP-TRAP-related protein) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-151
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The cytoplasmic tail domain (CTD) of P. berghei TRAP replaced with the CTD of TRAP of P. falciparum |
Phenotype |
Sporozoite; Liver stage; |
RMgm-268
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Sporozoite; |
RMgm-357
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details mutation: The mutant contains a mutated pkg gene with two FRT sites Details conditional mutagenesis: The FRTed sequenmce of pkg is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-683
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Insertion locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts; pbdhfr/ts) |
Phenotype |
Sporozoite; |
RMgm-684
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 (AMA1) Details mutation: The mutant contains a mutated ama1 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of ama1 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Insertion locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts; pbdhfr/ts) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-685
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0932000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Details mutation: The mutant contains a mutated ron4 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of ron4 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Insertion locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts; pbdhfr/ts) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-737
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1126900; Gene model (P.falciparum): PF3D7_0628200; Gene product: protein kinase PK4 | eukaryotic translation initiation factor 2-alpha kinase (PK4) Details mutation: The mutant contains a mutated pk4 gene with FRT-flanked TRAP 3' regulatory sequences Details conditional mutagenesis: The FRTed 3' regulatory sequence of pk4 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-747
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; |
RMgm-777
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Details mutation: canonical rhomboid motif AGGIIGG changed to VALIIGV |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-778
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Details mutation: canonical rhomboid motif AGGIIGG changed to FFFIIGG |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-779
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Details mutation: 140 amino acids of the juxtamembrane region deleted + rhomboid motif changed from AGGIIGG to FFFIIGG |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-967
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0314200; Gene model (P.falciparum): PF3D7_0217500; Gene product: calcium-dependent protein kinase 1 (cdpk1) Details mutation: The mutant contains a FRTed ORF of the cdpk1 locus Details conditional mutagenesis: The ORF of cdpk1 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-1024
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) Name tag: triple myc |
Phenotype |
Sporozoite; |
RMgm-1103
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The endogenous P. berghei trap gene replaced with the ortholog of P. vivax |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1317
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1335
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: The mutant contains a mutated exp2 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of exp2 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1338
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: The mutant contains a mutated exp2 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of exp2 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1344
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Details mutation: canonical rhomboid motif AGGIIGG changed to VALIIGV |
Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): PF3D7_1016900; Gene product: early transcribed membrane protein 10.3 | protein of early gametocyte 4 (UIS4, up-regulated in infective sporozoites; ETRAMP10.3) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (UIS4, up-regulated in infective sporozoites; ETRAMP10.3) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1360
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: 2 zinc-finger nucleases (ZFNL, ZFNLR) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS) Replacement locus: Gene model: Not available; Gene product: Not available |
Transgene |
Transgene not Plasmodium: a fusion of GFP and hdhfr Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: Not available; Gene product: Not available |
Phenotype |
Liver stage; |
RMgm-1365
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1028300; Gene model (P.falciparum): PF3D7_1414400; Gene product: serine/threonine protein phosphatase PP1 (PP1) Details mutation: The mutant contains a mutated pp1 gene with two FRT sites Details conditional mutagenesis: The FRTed sequenmce of pp1 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype | No phenotype has been described |
RMgm-1366
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1328000; Gene model (P.falciparum): PF3D7_1464600; Gene product: serine/threonine protein phosphatase UIS2, putative (UIS2) Details mutation: The mutant contains a mutated uis2 gene with two FRT sites Details conditional mutagenesis: The FRTed sequenmce of uis2 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Liver stage; |
RMgm-1505
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Name tag: GFP |
Phenotype |
Sporozoite; |
RMgm-1510
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (cdpk4) Details mutation: The mutant contains a FRTed ORF of the cdpk4 locus Details conditional mutagenesis: The ORF of cdpk4 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-3642
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-4067
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1302200; Gene model (P.falciparum): PF3D7_1302200; Gene product: early transcribed membrane protein 13 (ETRAMP13; UIS3) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative |
Phenotype |
Sporozoite; |
RMgm-4112
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Details mutation: The P. berghei trap gene replaced by P. falciparum trap |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4186
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; |
RMgm-4188
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0614300; Gene model (P.falciparum): PF3D7_0716600; Gene product: cysteine desulfurase (SufS) Details mutation: The mutant contains a FRTed 3'UTR of the SufS locus Details conditional mutagenesis: The 3'UTR of the SufS locus is removed in the oocyst/sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4402
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. berghei cs gene replaced by P. vivax cs VK210 (PVP01_0835600) |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: The endogenous P. berghei trap gene replaced with the trap gene of P. vivax (PVP01_1218700) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4457
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Details mutation: The P. berghei trap gene replaced by P. falciparum trap |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-4572
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1206800; Gene model (P.falciparum): PF3D7_1008600; Gene product: zinc finger (CCCH type) protein, putative (s1) |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4573
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1036400; Gene model (P.falciparum): PF3D7_1036400; Gene product: liver stage antigen 1 (LSA1) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (s1) |
Phenotype | No phenotype has been described |
RMgm-4574
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene Plasmodium: Gene model: Not available; Gene model (P.falciparum): PF3D7_0202100; Gene product: liver stage associated protein 2; Plasmodium exported protein (PHISTc), unknown function (LSAP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (s1) |
Phenotype | No phenotype has been described |
RMgm-4635
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0835600; Gene model (P.falciparum): PF3D7_0934800; Gene product: cAMP-dependent protein kinase catalytic subunit (PKAc) Details mutation: The mutant contains a FRTed ORF of the PKAc locus Details conditional mutagenesis: The ORF of PKAc is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-4680
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; |
RMgm-4701
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_0202100; Gene model (P.falciparum): PF3D7_0202100; Gene product: liver stage associated protein 2 | Plasmodium exported protein (PHISTc), unknown function (LSAP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (S1) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-4702
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1036400; Gene model (P.falciparum): PF3D7_1036400; Gene product: liver stage antigen 1 (LSA1) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative (S1) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-4703
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0309500; Gene model (P.falciparum): PF3D7_0212600; Gene product: secreted protein with altered thrombospondin repeat domain (SPATR) Details mutation: The mutant contains a FRTed (part of the) ORF of the spatr locus Details conditional mutagenesis: (Part of) the ORF of spatr is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-4930
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene not Plasmodium: GFPmut2 Promoter: Gene model: PY17X_1354800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein (TRAP) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
Phenotype |
Gametocyte/Gamete;
Oocyst;
Sporozoite; |
RMgm-4987
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. berghei csp gene replaced by P. falciparum csp |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Details mutation: The P. berghei trap gene replaced by P. falciparum trap |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-5096
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Disrupted | Gene model (rodent): PBANKA_1310700; Gene model (P.falciparum): PF3D7_1446900; Gene product: glutaminyl-peptide cyclotransferase, putative (glutamyl cyclase, QC) |
Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (P230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-5105
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1116000; Gene model (P.falciparum): PF3D7_0616500; Gene product: TRAP-like protein (TLP) |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Phenotype |
Sporozoite; |
RMgm-5106
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1306500; Gene model (P.falciparum): PF3D7_1442600; Gene product: TRAP-like protein | sporozoite-specific transmembrane protein S6 (TRAP-related protein, S6; sporozoite specific gene 6; UOS3; TREP) |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Phenotype |
Sporozoite; |
RMgm-5107
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1116000; Gene model (P.falciparum): PF3D7_0616500; Gene product: TRAP-like protein (TLP) |
Disrupted | Gene model (rodent): PBANKA_1306500; Gene model (P.falciparum): PF3D7_1442600; Gene product: TRAP-like protein | sporozoite-specific transmembrane protein S6 (TRAP-related protein, S6; sporozoite specific gene 6; UOS3; TREP) |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Phenotype |
Sporozoite; |
RMgm-5237
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) |
Phenotype |
Sporozoite; |
RMgm-5238
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (sporozoite surface protein 2; SSP2; SSP-2; TRAP) Details mutation: P. berghei trap replaced with different mutated forms of trap (point mutations) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-5401
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0922200; Gene model (P.falciparum): PF3D7_1126100; Gene product: autophagy-related protein 7, putative (Atg7) Details mutation: The mutant contains a FRTed ORF of the Atg7 locus Details conditional mutagenesis: The ORF of Atg7 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |