Search database by RMgm ID
RMgm-123
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0711600; Gene model (P.falciparum): PF3D7_0819200; Gene product: perforin-like protein 5 (PPLP5, Plasmodium perforin-like protein 5; Membrane Attack Complex) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-134
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0824200; Gene model (P.falciparum): PF3D7_0923300; Gene product: perforin-like protein 3 | membrane attack ookinete protein, putative (PPLP3; Plasmodium perforin like protein 3; Membrane attack Complex; MAOP) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-135
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1006300; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 | sporozoite micronemal protein essential for cell traversal (PPLP1; Plasmodium perforin like protein 1; Membrane attack Complex; SPECT2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-137
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1006300; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 | sporozoite micronemal protein essential for cell traversal (PPLP1; Plasmodium perforin like protein 1; Membrane attack Complex; SPECT2) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-138
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1355600; Gene model (P.falciparum): PF3D7_1342500; Gene product: sporozoite protein essential for cell traversal (SPECT, SPECT1) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-139
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1355600; Gene model (P.falciparum): PF3D7_1342500; Gene product: sporozoite protein essential for cell traversal (SPECT, SPECT1) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-839
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1432400; Gene model (P.falciparum): PF3D7_1216700; Gene product: perforin-like protein 2 (PPLP2) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-1296
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0711400; Gene model (P.falciparum): PF3D7_0819400; Gene product: perforin-like protein 4 (PPLP4) |
Phenotype |
Oocyst;
|
RMgm-1346
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1007700; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 | sporozoite micronemal protein essential for cell traversal (PLP1; PPLP1, SPECT2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1347
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1006300; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 | sporozoite micronemal protein essential for cell traversal (PLP1; PPLP1, SPECT2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1348
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1007700; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 | sporozoite micronemal protein essential for cell traversal (PLP1; PPLP1, SPECT2) |
Tagged | Gene model (rodent): PY17X_0934000; Gene model (P.falciparum): PF3D7_1116000; Gene product: rhoptry neck protein 4 (RON4) Name tag: mCherry |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1485
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1432400; Gene model (P.falciparum): PF3D7_1216700; Gene product: perforin-like protein 2 (PPLP2; PLP2) Name tag: mCherry |
Phenotype |
Gametocyte/Gamete;
|
RMgm-1500
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0303900; Gene model (P.falciparum): PF3D7_0206200; Gene product: pantothenate transporter (PAT) |
Phenotype |
Gametocyte/Gamete;
Oocyst;
Sporozoite; |
RMgm-1501
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0303900; Gene model (P.falciparum): PF3D7_0206200; Gene product: pantothenate transporter (PAT) Details mutation: The endogenous pat gene has been replaced with the P. falciparum 3D7 pat gene |
Phenotype | No phenotype has been described |
RMgm-1502
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0303900; Gene model (P.falciparum): PF3D7_0206200; Gene product: pantothenate transporter (PAT) Name tag: GFP |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Sporozoite; Liver stage; |
RMgm-1503
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0303900; Gene model (P.falciparum): PF3D7_0206200; Gene product: pantothenate transporter (PAT) Name tag: GFP |
Tagged | Gene model (rodent): PBANKA_1463000; Gene model (P.falciparum): PF3D7_1250100; Gene product: osmiophilic body protein G377 (Pfg377; G377) Name tag: mCherry |
Phenotype |
Gametocyte/Gamete;
|
RMgm-1504
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0303900; Gene model (P.falciparum): PF3D7_0206200; Gene product: pantothenate transporter (PAT) Name tag: GFP |
Tagged | Gene model (rodent): PBANKA_1432400; Gene model (P.falciparum): PF3D7_1216700; Gene product: perforin-like protein 2 (PPLP2; PLP2) Name tag: mCherry |
Phenotype |
Gametocyte/Gamete;
|
RMgm-1506
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0303900; Gene model (P.falciparum): PF3D7_0206200; Gene product: pantothenate transporter (PAT) Details mutation: 'promoter-swap' mutant; the promoter of PAT replaced by the promoter of PBANKA_1300700 (ccp1/lap) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4406
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1007700; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1; sporozoite micronemal protein essential for cell traversal (PLP1; PPLP1, SPECT2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-4461
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0711400; Gene model (P.falciparum): PF3D7_0819400; Gene product: perforin-like protein 4 (PPLP4) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4462
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0711400; Gene model (P.falciparum): PF3D7_0819400; Gene product: perforin-like protein 4 (PPLP4) Name tag: mCherry |
Phenotype |
Fertilization and ookinete;
|
RMgm-4577
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1224400; Gene model (P.falciparum): PF3D7_0806300; Gene product: ferlin, putative (ferlin-like protein, FLP) Details mutation: 'Promoter swap' mutant: the promoter of FLP replaced by the promoter of clag (PBANKA_1400600) |
Tagged | Gene model (rodent): PBANKA_1224400; Gene model (P.falciparum): PF3D7_0806300; Gene product: ferlin, putative (ferlin-like protein, FLP) Name tag: HA |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-4578
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1224400; Gene model (P.falciparum): PF3D7_0806300; Gene product: ferlin, putative (ferlin-like protein, FLP) Name tag: HA |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
|
RMgm-4914
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_0408700; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 (PLP1, PPLP1, SPECT2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3, UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-4918
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1006300; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 (PLP1, PPLP1, SPECT2) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; |
RMgm-4919
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PF3D7_0408700; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 (PLP1, PPLP1, SPECT2) Details mutation: The endogenous P. berghei plp1/spect2 gene replaced with the P. falciparum plp1/spect2 ortholog |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-5050
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_0711800; Gene model (P.falciparum): PF3D7_0319000; Gene product: perforin-like protein 5 (PLP5, PPLP5, Plasmodium perforin-like protein 5; Membrane Attack Complex) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-5267
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0808100; Gene model (P.falciparum): PF3D7_0317100; Gene product: 6-cysteine protein (B9) |
Disrupted | Gene model (rodent): PBANKA_1006300; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 | sporozoite micronemal protein essential for cell traversal (PLP1; PPLP1, SPECT2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-5268
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1002200; Gene model (P.falciparum): PF3D7_0404500; Gene product: 6-cysteine protein P52 (P36p; Pb36p; P52) |
Disrupted | Gene model (rodent): PBANKA_1006300; Gene model (P.falciparum): PF3D7_0408700; Gene product: perforin-like protein 1 | sporozoite micronemal protein essential for cell traversal (PLP1; PPLP1, SPECT2) |
Phenotype |
Sporozoite; Liver stage; |