RMgmDB - Rodent Malaria genetically modified Parasites
Search for genetically modified parasite lines by:
Search database by RMgm ID
85 results for: DHHC
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RMgm-595Malaria parasite P. berghei Genotype Transgene Transgene not Plasmodium: firefly luciferase
Promoter: Gene model: PBANKA_0402000; Gene model (P.falciparum): PF3D7_0303400; Gene product: palmitoyltransferase DHHC1
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type and/or d-type unit))
Transgene Transgene not Plasmodium: Renilla luciferase
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type and/or d-type unit))
Phenotype Asexual bloodstage; Oocyst; Sporozoite; Liver stage;
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RMgm-888Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0927300; Gene model (P.falciparum): PF3D7_1121000; Gene product: palmitoyltransferase DHHC3 (DHHC3) Phenotype Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
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RMgm-889Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1337800; Gene model (P.falciparum): PF3D7_1322500; Gene product: palmitoyltransferase DHHC5 (DHHC5) Phenotype Asexual bloodstage;
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RMgm-890Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0833300; Gene model (P.falciparum): PF3D7_0932500; Gene product: palmitoyltransferase DHHC6, putative (DHHC6) Phenotype Asexual bloodstage;
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RMgm-891Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_1243000; Gene model (P.falciparum): PF3D7_0528400; Gene product: palmitoyltransferase DHHC7 (DHHC7) Phenotype Asexual bloodstage;
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RMgm-892Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0932100; Gene model (P.falciparum): PF3D7_1115900; Gene product: palmitoyltransferase DHHC9 (DHHC9) Phenotype No phenotype has been described
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RMgm-893Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0512000; Gene model (P.falciparum): PF3D7_1027900; Gene product: palmitoyltransferase DHHC10, putative (DHHC10) Phenotype Asexual bloodstage;
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RMgm-894Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0312600; Gene model (P.falciparum): PF3D7_0215900; Gene product: palmitoyltransferase DHHC11, putative (DHHC11) Phenotype Asexual bloodstage;
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RMgm-895Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1420900; Gene model (P.falciparum): PF3D7_0714300; Gene product: palmitoyltransferase DHHC4, putative (DHHC4) Phenotype No phenotype has been described
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RMgm-896Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1419700; Gene model (P.falciparum): PF3D7_1321400; Gene product: palmitoyltransferase DHHC8, putative (DHHC8) Phenotype No phenotype has been described
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RMgm-897Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0927300; Gene model (P.falciparum): PF3D7_1121000; Gene product: palmitoyltransferase DHHC3 (DHHC3)
Name tag: triple-HA
Phenotype Asexual bloodstage; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
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RMgm-898Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1420900; Gene model (P.falciparum): PF3D7_0714300; Gene product: palmitoyltransferase DHHC4, putative (DHHC4)
Name tag: triple-HA
Phenotype Asexual bloodstage;
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RMgm-899Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1337800; Gene model (P.falciparum): PF3D7_1322500; Gene product: palmitoyltransferase DHHC5 (DHHC5)
Name tag: triple-HA
Phenotype Asexual bloodstage;
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RMgm-900Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0833300; Gene model (P.falciparum): PF3D7_0932500; Gene product: palmitoyltransferase DHHC6, putative (DHHC6)
Name tag: triple-HA
Phenotype Asexual bloodstage;
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RMgm-901Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1243000; Gene model (P.falciparum): PF3D7_0528400; Gene product: palmitoyltransferase DHHC7 (DHHC7)
Name tag: triple-HA
Phenotype Asexual bloodstage;
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RMgm-902Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_1419700; Gene model (P.falciparum): PF3D7_1321400; Gene product: palmitoyltransferase DHHC8, putative (DHHC8)
Name tag: triple-HA
Phenotype Asexual bloodstage;
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RMgm-903Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0932100; Gene model (P.falciparum): PF3D7_1115900; Gene product: palmitoyltransferase DHHC9 (DHHC9)
Name tag: triple-HA
Phenotype Asexual bloodstage; Oocyst; Sporozoite; Liver stage;
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RMgm-904Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0512000; Gene model (P.falciparum): PF3D7_1027900; Gene product: palmitoyltransferase DHHC10, putative (DHHC10)
Name tag: triple-HA
Phenotype Asexual bloodstage;
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RMgm-905Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0312600; Gene model (P.falciparum): PF3D7_0215900; Gene product: palmitoyltransferase DHHC11, putative (DHHC11)
Name tag: triple-HA
Phenotype Asexual bloodstage;
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RMgm-1349Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0108300; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2)
Details mutation: 'promoter-swap' mutant; the promoter of DHHC2 replaced by the promoter of PBANKA_140060 (clag)
Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Fertilization and ookinete; Oocyst;
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RMgm-1350Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_0108300; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2) Phenotype No phenotype has been described
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RMgm-1351Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PBANKA_0108300; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2)
Details mutation: 'promoter-swap' mutant; the promoter of DHHC2 replaced by the promoter of PBANKA_140060 (clag)
Phenotype Fertilization and ookinete; Oocyst;
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RMgm-1352Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0108300; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2)
Name tag: GFP
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-1353Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0108300; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2)
Name tag: GFP
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-1470Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0512000; Gene model (P.falciparum): PF3D7_1027900; Gene product: palmitoyltransferase DHHC10, putative (DHHC10) Transgene Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV)
Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-1471Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0512000; Gene model (P.falciparum): PF3D7_1027900; Gene product: palmitoyltransferase DHHC10, putative (DHHC10) Transgene Transgene not Plasmodium: RFP
Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2)
3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene not Plasmodium: GFP (gfp-mut3)
Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative
3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-1472Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0512000; Gene model (P.falciparum): PF3D7_1027900; Gene product: palmitoyltransferase DHHC10, putative (DHHC10)
Name tag: GFP
Phenotype Fertilization and ookinete;
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RMgm-1473Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PBANKA_0512000; Gene model (P.falciparum): PF3D7_1027900; Gene product: palmitoyltransferase DHHC10, putative (DHHC10)
Name tag: GFP
Tagged Gene model (rodent): PBANKA_0204500; Gene model (P.falciparum): PF3D7_0109100; Gene product: LCCL domain-containing protein (LAP3; LCCL/lectin adhesive-like protein 2; CCp5)
Name tag: mCherry
Phenotype Fertilization and ookinete;
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RMgm-1474Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0512000; Gene model (P.falciparum): PF3D7_1027900; Gene product: palmitoyltransferase DHHC10, putative (DHHC10) Tagged Gene model (rodent): PBANKA_1300700; Gene model (P.falciparum): PF3D7_1475500; Gene product: LCCL domain-containing protein (LAP2; LCCL/lectin adhesive-like protein 2; CCp1)
Name tag: EGFP
Transgene Transgene not Plasmodium: RFP
Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2)
3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Transgene Transgene not Plasmodium: GFP (gfp-mut3)
Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative
3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam)
Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype Gametocyte/Gamete; Fertilization and ookinete;
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RMgm-1804Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0312600; Gene model (P.falciparum): PF3D7_0215900; Gene product: palmitoyltransferase DHHC11, putative Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
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RMgm-2456Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0833300; Gene model (P.falciparum): PF3D7_0932500; Gene product: palmitoyltransferase DHHC6, putative Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
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RMgm-2604Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_0927300; Gene model (P.falciparum): PF3D7_1121000; Gene product: palmitoyltransferase DHHC3 Phenotype No phenotype has been described
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RMgm-2637Malaria parasite P. berghei Genotype Disrupted Gene model (rodent): PBANKA_0932100; Gene model (P.falciparum): PF3D7_1115900; Gene product: palmitoyltransferase DHHC9 Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;
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RMgm-3381Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1243000; Gene model (P.falciparum): PF3D7_0528400; Gene product: palmitoyltransferase DHHC7 Phenotype No phenotype has been described
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RMgm-3831Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1419700; Gene model (P.falciparum): PF3D7_1321400; Gene product: palmitoyltransferase DHHC8, putative Phenotype No phenotype has been described
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RMgm-3840Malaria parasite P. berghei Genotype Genetic modification not successful Disrupted Gene model (rodent): PBANKA_1420900; Gene model (P.falciparum): PF3D7_0714300; Gene product: palmitoyltransferase DHHC4, putative Phenotype No phenotype has been described
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RMgm-4483Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta)
Name tag: HA
Phenotype Fertilization and ookinete;
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RMgm-4484Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta)
Name tag: HA
Phenotype Fertilization and ookinete;
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RMgm-4485Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta)
Name tag: HA
Phenotype Fertilization and ookinete;
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RMgm-4486Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta)
Name tag: mScarlet
Phenotype Fertilization and ookinete;
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RMgm-4487Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0911700; Gene model (P.falciparum): PF3D7_1138400; Gene product: guanylyl cyclase (GCalpha)
Name tag: HA
Phenotype Asexual bloodstage;
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RMgm-4488Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0619700; Gene model (P.falciparum): PF3D7_0719500; Gene product: LEM3/CDC50 family protein, putative (CDC50a)
Name tag: HA
Phenotype Asexual bloodstage;
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RMgm-4489Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0916600; Gene model (P.falciparum): PF3D7_1133300; Gene product: LEM3/CDC50 family protein, putative (CDC50b)
Name tag: HA
Phenotype No phenotype has been described
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RMgm-4490Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0916600; Gene model (P.falciparum): PF3D7_1133300; Gene product: LEM3/CDC50 family protein, putative (CDC50c)
Name tag: HA
Phenotype No phenotype has been described
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RMgm-4491Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1370200; Gene model (P.falciparum): PF3D7_1351700; Gene product: inner membrane complex protein 1f, putative (IMC1f)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4492Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1243800; Gene model (P.falciparum): PF3D7_0525800; Gene product: inner membrane complex protein 1g, putative (IMC1g)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4493Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0707400; Gene model (P.falciparum): PF3D7_0823500; Gene product: inner membrane complex protein 1i, putative (IMC1i)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4494Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1121700; Gene model (P.falciparum): PY17X_1121700; Gene product: inner membrane complex protein 1j, putative (IMC1j)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4495Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1360600; Gene model (P.falciparum): PF3D7_1341800; Gene product: inner membrane complex protein 1j, putative (IMC1k)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4496Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1028100; Gene model (P.falciparum): PF3D7_1417000; Gene product: inner membrane complex protein 1l, putative (IMC1l)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4497Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0514100; Gene model (P.falciparum): PF3D7_1028900; Gene product: inner membrane complex protein 1m, putative (IMC1m)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4498Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1240600; Gene model (P.falciparum): PF3D7_0522600; Gene product: inner membrane complex protein (alvX)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4499Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1462100; Gene model (P.falciparum): PF3D7_1246400; Gene product: myosin A tail domain interacting protein; myosin light chain 1 (MTIP, MLC1)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4500Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1412750; Gene model (P.falciparum): PF3D7_1312450; Gene product: apical ring associated protein 1, putative (ARA1)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4501Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0931400; Gene model (P.falciparum): PF3D7_1118700; Gene product: myosin light chain B (MLC-B)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4502Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1040200; Gene model (P.falciparum): PF3D7_1404300; Gene product: secreted ookinete adhesive protein, putative (SOAP)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4503Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0513100; Gene model (P.falciparum): PF3D7_1027900; Gene product: palmitoyltransferase DHHC10, putative (DHHC10)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4504Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1225400; Gene model (P.falciparum): PF3D7_0808450; Gene product: protein MPODD, putative (MPODD)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4505Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1338400; Gene model (P.falciparum): PF3D7_1470500; Gene product: phosphodiesterase delta, putative (pdeδ, PDEdelta)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4506Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1009800; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG)
Name tag: c-myc
Phenotype No phenotype has been described
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RMgm-4507Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1)
Name tag: HA
Phenotype No phenotype has been described
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RMgm-4508Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PY17X_1328100; Gene product: inner membrane complex sub-compartment protein 3, putative (ISP3)
Name tag: HA
Phenotype No phenotype has been described
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RMgm-4509Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta) Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-4510Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0619700; Gene model (P.falciparum): PF3D7_0719500; Gene product: LEM3/CDC50 family protein, putative (CDC50a) Phenotype Fertilization and ookinete; Oocyst; Sporozoite;
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RMgm-4511Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta) Disrupted Gene model (rodent): PY17X_0619700; Gene model (P.falciparum): PF3D7_0719500; Gene product: LEM3/CDC50 family protein, putative (CDC50a) Phenotype Fertilization and ookinete; Oocyst;
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RMgm-4512Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1338400; Gene model (P.falciparum): PF3D7_1470500; Gene product: phosphodiesterase delta, putative (pdeδ) Phenotype Fertilization and ookinete; Oocyst;
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RMgm-4513Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: phosphodiesterase delta, putative (isp1) Phenotype Fertilization and ookinete; Oocyst;
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RMgm-4514Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta) Disrupted Gene model (rodent): PY17X_1338400; Gene model (P.falciparum): PF3D7_1470500; Gene product: phosphodiesterase delta, putative (pdeδ) Phenotype Fertilization and ookinete;
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RMgm-4515Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1338400; Gene model (P.falciparum): PF3D7_1470500; Gene product: phosphodiesterase delta, putative (pdeδ) Disrupted Gene model (rodent): PY17X_0619700; Gene model (P.falciparum): PF3D7_0719500; Gene product: LEM3/CDC50 family protein, putative (CDC50a) Phenotype Fertilization and ookinete;
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RMgm-4516Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0619700; Gene model (P.falciparum): PF3D7_0719500; Gene product: LEM3/CDC50 family protein, putative (CDC50a) Disrupted Gene model (rodent): PY17X_0410700; Gene model (P.falciparum): PF3D7_0310100; Gene product: calcium-dependent protein kinase 3 (CDPK3) Phenotype Fertilization and ookinete;
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RMgm-4517Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_0410700; Gene model (P.falciparum): PF3D7_0310100; Gene product: calcium-dependent protein kinase 3 (CDPK3) Disrupted Gene model (rodent): PY17X_1138200; Gene model (P.falciparum): PF3D7_1360500; Gene product: guanylyl cyclase beta (GCbeta) Phenotype Fertilization and ookinete;
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RMgm-4889Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1) Phenotype Fertilization and ookinete;
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RMgm-4890Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) Phenotype Fertilization and ookinete;
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RMgm-4891Malaria parasite P. yoelii Genotype Disrupted Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1) Disrupted Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) Phenotype Fertilization and ookinete;
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RMgm-4892Malaria parasite P. yoelii Genotype Mutated Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1)
Details mutation: N-terminal cysteines (C7/C8) replaced with A7/A8 (alanine) and C-terminal BFP::3V5 tag
Phenotype Fertilization and ookinete;
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RMgm-4893Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1)
Name tag: sextuple HA epitope (6HA)
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst;
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RMgm-4894Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3)
Name tag: sextuple HA epitope (6HA)
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst;
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RMgm-4895Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_1328100; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3)
Name tag: sextuple HA epitope (6HA)
Tagged Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1)
Name tag: 3xV5
Phenotype Fertilization and ookinete;
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RMgm-4896Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PY17X_0109900; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2)
Name tag: sextuple HA epitope (6HA)
Phenotype Gametocyte/Gamete; Fertilization and ookinete;
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RMgm-4897Malaria parasite P. yoelii Genotype Genetic modification not successful Disrupted Gene model (rodent): PY17X_0109900; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2) Phenotype No phenotype has been described
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RMgm-4898Malaria parasite P. yoelii Genotype Mutated Gene model (rodent): PY17X_0109900; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2)
Details mutation: 'promoter-swap' mutant; the promoter of DHHC2 replaced by the promoter of PY17X_1402200 (clag)
Phenotype Fertilization and ookinete; Oocyst;
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RMgm-4899Malaria parasite P. yoelii Genotype Mutated Gene model (rodent): PY17X_0109900; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2)
Details mutation: Glycine 128 changed to alanine
Tagged Gene model (rodent): PY17X_1212600; Gene model (P.falciparum): PF3D7_1011000; Gene product: inner membrane complex sub-compartment protein 1 (ISP1)
Name tag: sextuple HA epitope (6HA)
Phenotype Fertilization and ookinete;
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RMgm-5181Malaria parasite P. yoelii Genotype Tagged Gene model (rodent): PBANKA_0108300; Gene model (P.falciparum): PF3D7_0609800; Gene product: palmitoyltransferase DHHC2, putative (DHHC2)
Name tag: AID degron motif (mAID-2HA)
Transgene Transgene not Plasmodium: the plant Oryza sativa auxin receptor transport inhibitor response 1 (TIR1)
Promoter: Gene model: PY17X_1134900; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a)
3'UTR: Gene model: PY17X_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR-TS)
Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein P230p
Phenotype Asexual bloodstage;
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RMgm-5634Malaria parasite P. berghei Genotype Tagged Gene model (rodent): PbANKA_1240600; Gene model (P.falciparum): PF3D7_0525800; Gene product: inner membrane complex protein 1g (IMC1g)
Name tag: triple-HA
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete;
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RMgm-5635Malaria parasite P. berghei Genotype Mutated Gene model (rodent): PbANKA_1240600; Gene model (P.falciparum): PF3D7_0525800; Gene product: inner membrane complex protein 1g (IMC1g)
Details mutation: a fusion of IMC1g with HA-tagged mutant E. coli DHFR (cDDHA)
Phenotype Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;