Search database by RMgm ID
RMgm-311
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: GFP |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-325
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) |
Phenotype | No phenotype has been described |
RMgm-357
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details mutation: The mutant contains a mutated pkg gene with two FRT sites Details conditional mutagenesis: The FRTed sequenmce of pkg is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-544
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) |
Phenotype | No phenotype has been described |
RMgm-999
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: triple-HA |
Phenotype |
Fertilization and ookinete;
|
RMgm-1000
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details mutation: a mutated pkg in which the threonine gatekeeper residue ((T619Q) is mutated to glutamine |
Tagged | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: triple-HA |
Phenotype |
Fertilization and ookinete;
|
RMgm-1094
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details mutation: The P. berghei pkg gene replaced by the P. falciparum pkg gene |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-1191
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Other modification | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants |
Phenotype | No phenotype has been described |
RMgm-1508
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: triple-HA |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-1509
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details mutation: a mutated pkg in which the threonine gatekeeper residue ((T619Q) is mutated to glutamine |
Tagged | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: triple-HA |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-4506
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_1009800; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: c-myc |
Phenotype | No phenotype has been described |
RMgm-4552
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) |
Mutated | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details mutation: a mutated pkg in which the threonine gatekeeper residue ((T619Q) is mutated to glutamine |
Tagged | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: triple-HA |
Phenotype |
Asexual bloodstage;
|