37 results for: ptex150

1. RMgm-297

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_1008500; Gene model (P.falciparum): PF3D7_1436300; Gene product: translocon component PTEX150 (PTEX150, Plasmodium translocon of exported proteins)
   Phenotype	No phenotype has been described

   
   
2. RMgm-914

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 | chaperone protein ClpB2 (HSP101)
   Phenotype	No phenotype has been described

   
   
3. RMgm-915

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_1008500; Gene model (P.falciparum): PF3D7_1436300; Gene product: translocon component PTEX150 (PTEX150)
   Phenotype	No phenotype has been described

   
   
4. RMgm-916

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2)
   Phenotype	No phenotype has been described

   
   
5. RMgm-917

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_0941300; Gene model (P.falciparum): PF3D7_1105600; Gene product: translocon component PTEX88 (PTEX88)
   Phenotype	No phenotype has been described

   
   
6. RMgm-918

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_1358000; Gene model (P.falciparum): PF3D7_1345100; Gene product: thioredoxin 2 (TRX2)
   Phenotype	Asexual bloodstage;

   
   
7. RMgm-919

   Malaria parasite	P. berghei
   Genotype
   Tagged	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 | chaperone protein ClpB2 (HSP101) Name tag: triple haemagluttinin (HA)/single streptactin II
   Phenotype	Asexual bloodstage; Sporozoite; Liver stage;

   
   
8. RMgm-920

   Malaria parasite	P. berghei
   Genotype
   Tagged	Gene model (rodent): PBANKA_1008500; Gene model (P.falciparum): PF3D7_1436300; Gene product: translocon component PTEX150 (PTEX150) Name tag: triple haemagluttinin (HA)/single streptactin II
   Phenotype	Asexual bloodstage; Sporozoite; Liver stage;

   
   
9. RMgm-921

   Malaria parasite	P. berghei
   Genotype
   Tagged	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Name tag: triple haemagluttinin (HA)/single streptactin II
   Phenotype	Asexual bloodstage; Gametocyte/Gamete; Sporozoite; Liver stage;

   
   
10. RMgm-922

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_0941300; Gene model (P.falciparum): PF3D7_1105600; Gene product: translocon component PTEX88 (PTEX88) Name tag: triple haemagluttinin (HA)/single streptactin II
    Phenotype	Asexual bloodstage;

    
    
11. RMgm-923

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_1358000; Gene model (P.falciparum): PF3D7_1345100; Gene product: thioredoxin 2 (TRX2) Name tag: triple haemagluttinin (HA)/single streptactin II
    Phenotype	Asexual bloodstage; Gametocyte/Gamete;

    
    
12. RMgm-942

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_0941300; Gene model (P.falciparum): PF3D7_1105600; Gene product: translocon component PTEX88
    Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0941300; Gene model (P.falciparum): PF3D7_1105600; Gene product: translocon component PTEX88 3'UTR: Gene model: PBANKA_1426700; Gene product: dihydropteroate synthetase, putative (DHPS; PPPK) Replacement locus: Gene model: PBANKA_0941300; Gene product: translocon component PTEX88
    Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (Dhfs-fpgs) Insertion locus: Gene model: PBANKA_0941300; Gene product: translocon component PTEX88
    Phenotype	Asexual bloodstage;

    
    
13. RMgm-943

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_1358000; Gene model (P.falciparum): PF3D7_1345100; Gene product: thioredoxin 2 (TRX2)
    Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_1358000; Gene model (P.falciparum): PF3D7_1345100; Gene product: thioredoxin 2 3'UTR: Gene model: PBANKA_1426700; Gene product: dihydropteroate synthetase, putative (DHPS; PPPK) Replacement locus: Gene model: PBANKA_1358000; Gene product: thioredoxin 2
    Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (Dhfs-fpgs) Insertion locus: Gene model: PBANKA_1358000; Gene product: thioredoxin 2
    Phenotype	Asexual bloodstage;

    
    
14. RMgm-944

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2)
    Phenotype	No phenotype has been described

    
    
15. RMgm-945

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 | chaperone protein ClpB2 (HSP101)
    Phenotype	No phenotype has been described

    
    
16. RMgm-946

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_1008500; Gene model (P.falciparum): PF3D7_1436300; Gene product: translocon component PTEX150 (PTEX150, Plasmodium translocon of exported proteins)
    Phenotype	No phenotype has been described

    
    
17. RMgm-950

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_0941300; Gene model (P.falciparum): PF3D7_1105600; Gene product: translocon component PTEX88 Name tag: mCherry-3xMyc
    Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: PBANKA_0941300; Gene product: translocon component PTEX88
    Phenotype	Asexual bloodstage; Gametocyte/Gamete;

    
    
18. RMgm-951

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_1358000; Gene model (P.falciparum): PF3D7_1345100; Gene product: thioredoxin 2 (TRX2) Name tag: mCherry-3xMyc
    Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: PBANKA_1358000; Gene product: thioredoxin 2 (TRX2)
    Phenotype	Asexual bloodstage; Gametocyte/Gamete;

    
    
19. RMgm-1102

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 | chaperone protein ClpB2 (HSP101) Details mutation: The hsp101 promoter modified to contain a tet-inducible promoter and TRAD4 activating domain Details conditional mutagenesis: Downregulation of HSP101 expression by addition of the tetracycline derivative ATc
    Phenotype	Asexual bloodstage;

    
    
20. RMgm-1325

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 | chaperone protein ClpB2 (HSP101) Name tag: mCherry-3xMyc
    Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: Not available; Gene product: Not available Insertion locus: Gene model: PBANKA_0931200; Gene product: heat shock protein 101 (HSP101)
    Phenotype	Asexual bloodstage; Oocyst; Sporozoite; Liver stage;

    
    
21. RMgm-1326

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 | chaperone protein ClpB2 (HSP101) Name tag: mCherry-3xMyc
    Phenotype	Asexual bloodstage;

    
    
22. RMgm-1327

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 | chaperone protein ClpB2 (HSP101) Name tag: mCherry-3xMyc
    Phenotype	Asexual bloodstage;

    
    
23. RMgm-1328

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Name tag: mCherry-3xMyc
    Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: Not available; Gene product: Not available Insertion locus: Gene model: PBANKA_1334300; Gene product: exported protein 2 (EXP2)
    Phenotype	Asexual bloodstage; Oocyst; Sporozoite; Liver stage;

    
    
24. RMgm-1329

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Name tag: mCherry-3xMyc
    Phenotype	Asexual bloodstage;

    
    
25. RMgm-1330

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_0941300; Gene model (P.falciparum): PF3D7_1105600; Gene product: translocon component PTEX88 (PTEX88) Name tag: GFP
    Phenotype	Asexual bloodstage;

    
    
26. RMgm-1331

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Tagged	Gene model (rodent): PBANKA_1008500; Gene model (P.falciparum): PF3D7_1436300; Gene product: translocon component PTEX150 (PTEX150) Name tag: mCherry-3xMyc
    Phenotype	No phenotype has been described

    
    
27. RMgm-1335

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: The mutant contains a mutated exp2 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of exp2 is removed in the sporozoite stage by the Flp/FRT system
    Transgene	Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2)
    Phenotype	Sporozoite; Liver stage;

    
    
28. RMgm-1336

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: The mutant contains a mutated exp2 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of exp2 is removed in the sporozoite stage by the Flp/FRT system
    Transgene	Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (UIS4) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (UIS4)
    Phenotype	Sporozoite; Liver stage;

    
    
29. RMgm-1337

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: The mutant contains a mutated exp2 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of exp2 is removed in the sporozoite stage by the Flp/FRT system
    Transgene	Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (UIS4) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (UIS4)
    Phenotype	Sporozoite; Liver stage;

    
    
30. RMgm-1338

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: The mutant contains a mutated exp2 gene with two FRT sites Details conditional mutagenesis: The FRTed sequence of exp2 is removed in the sporozoite stage by the Flp/FRT system
    Transgene	Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Insertion locus: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2)
    Phenotype	Sporozoite; Liver stage;

    
    
31. RMgm-2746

    Malaria parasite	P. berghei
    Genotype
    Genetic modification not successful
    Disrupted	Gene model (rodent): PBANKA_1008500; Gene model (P.falciparum): PF3D7_1436300; Gene product: translocon component PTEX150
    Phenotype	No phenotype has been described

    
    
32. RMgm-5155

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene Plasmodium: Gene model: PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 (HSP101) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS) Replacement locus: Gene model: Not available; Gene product: Not available
    Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS) Replacement locus: Gene model: Not available; Gene product: Not available
    Phenotype	Asexual bloodstage; Liver stage;

    
    
33. RMgm-5156

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 (HSP101) Details mutation: The promoter of hsp101 replaced by the promoter of ptex150
    Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS) Replacement locus: Gene model: Not available; Gene product: Not available
    Phenotype	No phenotype has been described

    
    
34. RMgm-5257

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: Exp2, C-terminally tagged with the glucosamine-activated glmS ribozyme, mRuby, GFP and 3xHA
    Phenotype	Asexual bloodstage; Liver stage;

    
    
35. RMgm-5258

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_1334300; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Details mutation: Exp2, C-terminally tagged with the glucosamine-activated glmS ribozyme, 3xHA and nanoluciferase
    Phenotype	Liver stage;

    
    
36. RMgm-5275

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_0931200; Gene model (P.falciparum): PF3D7_1116800; Gene product: heat shock protein 101 | chaperone protein ClpB2 (HSP101) Name tag: KDEL ER-retrieval sequence
    Phenotype	Asexual bloodstage;

    
    
37. RMgm-5276

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_1008500; Gene model (P.falciparum): PF3D7_1436300; Gene product: translocon component PTEX150 (PTEX150, Plasmodium translocon of exported proteins) Name tag: KDEL ER-retrieval sequence
    Phenotype	Asexual bloodstage;