RMgmDB - Rodent Malaria genetically modified Parasites

RMgm-1145

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1334700; Gene model (P.falciparum): PF3D7_1471500; Gene product: transmembrane protein 43, putative Name tag: GFP
Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

RMgm-1146

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0720900; Gene model (P.falciparum): PF3D7_0418800; Gene product: MOLO1 domain-containing protein, putative Name tag: GFP
Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

RMgm-1147

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0720900; Gene model (P.falciparum): PF3D7_0418800; Gene product: MOLO1 domain-containing protein, putative
Phenotype	Oocyst; Sporozoite; Liver stage;

RMgm-1148

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CS; CSP) Details mutation: The endogenous cs gene with a cs gene lacking the repeat region
Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Oocyst; Sporozoite;

RMgm-1149

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CS; CSP) Details mutation: The endogenous cs gene with a cs gene lacking the repeat region and the NH2-terminus
Phenotype	Oocyst; Sporozoite;

RMgm-1150

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1113400; Gene model (P.falciparum): PF3D7_0513700; Gene product: secreted ookinete protein, putative \| 6-cysteine protein (secreted ookinete protein, putative; PSOP12) Name tag: EGFP
Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

RMgm-1151

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1219100; Gene model (P.falciparum): PF3D7_0708600; Gene product: inner membrane complex protein 1d, putative (IMC1d) Name tag: GFP
Phenotype	Fertilization and ookinete;

RMgm-1152

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1219100; Gene model (P.falciparum): PF3D7_0708600; Gene product: inner membrane complex protein 1d, putative (IMC1d)
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_1219100; Gene model (P.falciparum): PF3D7_0708600; Gene product: inner membrane complex protein 1d, putative (IMC1d) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_1219100; Gene product: inner membrane complex protein 1d
Phenotype	No phenotype has been described

RMgm-1153

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PBANKA_1243100; Gene model (P.falciparum): PF3D7_0528500; Gene product: F-actin-capping protein subunit alpha, putative (CPalpha, CPα)
Phenotype	No phenotype has been described

RMgm-1154

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1243100; Gene model (P.falciparum): PF3D7_0528500; Gene product: F-actin-capping protein subunit alpha, putative (CPalpha, CPα) Details mutation: P. berghei cpα replacement with the complete P. falciparum cpα gene
Phenotype	Oocyst; Sporozoite;

RMgm-1155

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Mutated	Gene model (rodent): PBANKA_1243100; Gene model (P.falciparum): PF3D7_0528500; Gene product: F-actin-capping protein subunit alpha, putative (CPalpha, CPα) Details mutation: P. berghei cpα replacement with a truncated (27bp C-terminal tail) P. falciparum cpα
Phenotype	No phenotype has been described

RMgm-1156

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1232400; Gene model (P.falciparum): PF3D7_0517600; Gene product: F-actin-capping protein subunit beta, putative (CPbeta, CPβ, UIS17, upregulated in infectious sporozoites gene 17) Details mutation: P. berghei cpβ replacement with the complete P. falciparum cpβ gene
Phenotype	Oocyst; Sporozoite;

RMgm-1157

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_1243100; Gene model (P.falciparum): PF3D7_0528500; Gene product: F-actin-capping protein subunit alpha, putative (CPalpha, CPα) Details mutation: P. berghei cpα replacement with the complete P. falciparum cpα gene
Mutated	Gene model (rodent): PBANKA_1232400; Gene model (P.falciparum): PF3D7_0517600; Gene product: F-actin-capping protein subunit beta, putative (CPbeta, CPβ, UIS17, upregulated in infectious sporozoites gene 17) Details mutation: P. berghei cpα and cpβ gene replacement with the P. falciparum cpα and cpβ orthologs
Phenotype	Oocyst; Sporozoite;

RMgm-1158

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PBANKA_1237800; Gene model (P.falciparum): PF3D7_0523000; Gene product: multidrug resistance protein 1 \| ABC transporter B family member 1 (MDR1; ABCB1; Pgh1)
Phenotype	No phenotype has been described

RMgm-1159

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PBANKA_0401200; Gene model (P.falciparum): PF3D7_0302600; Gene product: ABC transporter B family member 4, putative (MDR4 (multidrug resistance protein 4); ABCB4)
Phenotype	No phenotype has been described

RMgm-1160

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PBANKA_1364800; Gene model (P.falciparum): PF3D7_1352100; Gene product: ABC transporter B family member 6, putative (MDR6 (multidrug resistance protein 6); ABCB6)
Phenotype	No phenotype has been described

RMgm-1161

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PBANKA_0608300; Gene model (P.falciparum): PF3D7_1209900; Gene product: ABC transporter B family member 7, putative (MDR7 (multidrug resistance protein 7); ABCB7)
Phenotype	No phenotype has been described

RMgm-1165

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1311700; Gene model (P.falciparum): PF3D7_1447900; Gene product: multidrug resistance protein 2 \| ABC transporter B family member 2 (MDR2, ABCB2)
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Oocyst; Sporozoite; Liver stage;

RMgm-1166

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1311700; Gene model (P.falciparum): PF3D7_1447900; Gene product: multidrug resistance protein 2 \| ABC transporter B family member 2 (MDR2, ABCB2)
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 (ama-1) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Oocyst; Sporozoite; Liver stage;

RMgm-1167

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0903500; Gene model (P.falciparum): PF3D7_1145500; Gene product: ABC transporter B family member 3, putative (MDR3, ABCB3)
Phenotype	Asexual bloodstage;

RMgm-1168

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1353300; Gene model (P.falciparum): PF3D7_1339900; Gene product: ABC transporter B family member 5, putative (MDR5, ABCB5)
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Asexual bloodstage; Oocyst; Sporozoite; Liver stage;

RMgm-1169

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1353300; Gene model (P.falciparum): PF3D7_1339900; Gene product: ABC transporter B family member 5, putative (MDR5, ABCB5)
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 (ama-1) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Asexual bloodstage; Oocyst; Sporozoite; Liver stage;

RMgm-1170

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1460700; Gene model (P.falciparum): PF3D7_1247800; Gene product: dipeptidyl aminopeptidase 2 (DPAP2)
Phenotype	No phenotype has been described

RMgm-1171

Malaria parasite	P. berghei
Genotype
Mutated	Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: the H-2K(d) epitope SYIPSAEKI mutated to SIINFEKL, an H-2K(b) epitope and deletion of N-terminus
Phenotype	Sporozoite; Liver stage;

RMgm-1172

Malaria parasite	P. yoelii
Genotype
Genetic modification not successful
Disrupted	Gene model (rodent): PY17X_1339000; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2)
Phenotype	No phenotype has been described

RMgm-1173

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_1339000; Gene model (P.falciparum): PF3D7_1471100; Gene product: exported protein 2 (EXP2) Name tag: triple-HA
Phenotype	Asexual bloodstage;

RMgm-1174

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_1351500; Gene model (P.falciparum): PF3D7_1337800; Gene product: calcium-dependent protein kinase 5 (CDPK5) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1175

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0925200; Gene model (P.falciparum): PF3D7_1123100; Gene product: calcium-dependent protein kinase 7 (CDPK7) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1176

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0311400; Gene model (P.falciparum): PF3D7_0214600; Gene product: serine/threonine protein kinase, putative Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1177

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0835600; Gene model (P.falciparum): PF3D7_0934800; Gene product: cAMP-dependent protein kinase catalytic subunit (PKAc; PKA) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1178

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0903800; Gene model (P.falciparum): PF3D7_1145200; Gene product: serine/threonine protein kinase, putative Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1179

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0912100; Gene model (P.falciparum): PF3D7_1136500; Gene product: casein kinase 1 (CK1) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1180

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0717300; Gene model (P.falciparum): PF3D7_0415300; Gene product: cdc2-related protein kinase 3 (CRK3) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1181

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_1309200; Gene model (P.falciparum): PF3D7_1445400; Gene product: protein serine/threonine kinase-1 (CLK1; LAMMER, PSK1) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1182

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0933000; Gene model (P.falciparum): PF3D7_1114700; Gene product: serine/threonine protein kinase, putative (CLK3) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1183

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0808000; Gene model (P.falciparum): PF3D7_0317200; Gene product: cdc2-related protein kinase 4 (CRK4) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1184

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0901100; Gene model (P.falciparum): PF3D7_1148000; Gene product: serine/threonine protein kinase, putative Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1185

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0938600; Gene model (P.falciparum): PF3D7_1108400; Gene product: casein kinase 2, alpha subunit (CK2alpha; CK2) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1186

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_1010900; Gene model (P.falciparum): PF3D7_1433900; Gene product: protein kinase, putative Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1187

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_1443000; Gene model (P.falciparum): PF3D7_1228300; Gene product: NIMA related kinase 1 (NEK1) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1188

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_1350900; Gene model (P.falciparum): PF3D7_1337100; Gene product: protein kinase 6 (PK6) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1189

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0805600; Gene model (P.falciparum): PF3D7_0708300; Gene product: EKC/KEOPS complex subunit BUD32 (BUD32) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1190

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_1225000; Gene model (P.falciparum): PF3D7_0805700; Gene product: serine/threonine protein kinase, FIKK family (FIKK8; TSTK0) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1191

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1192

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_1126900; Gene model (P.falciparum): PF3D7_0628200; Gene product: protein kinase PK4 \| eukaryotic translation initiation factor 2-alpha kinase (PK4; PERK) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1193

Malaria parasite	P. berghei
Genotype
Genetic modification not successful
Other modification	Gene model (rodent): PBANKA_0521400; Gene model (P.falciparum): PF3D7_0420100; Gene product: serine/threonine protein kinase RIO2 (RIO2) Details modification: Unsuccessful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1194

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0401100; Gene model (P.falciparum): PF3D7_0302100; Gene product: serine/threonine protein kinase (SRPK1; CLK4) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	Asexual bloodstage;

RMgm-1195

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0827100; Gene model (P.falciparum): PF3D7_0926300; Gene product: protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	Asexual bloodstage;

RMgm-1196

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1019800; Gene model (P.falciparum): PF3D7_1423600; Gene product: calcium-dependent protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	Asexual bloodstage;

RMgm-1197

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1122700; Gene model (P.falciparum): PF3D7_0623800; Gene product: tyrosine kinase-like protein, putative (TKL4) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	Asexual bloodstage;

RMgm-1198

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0408200; Gene model (P.falciparum): PF3D7_0310100; Gene product: calcium-dependent protein kinase 3 (CDPK3) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1199

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0409400; Gene model (P.falciparum): PF3D7_0311400; Gene product: protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1200

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1201

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0616700; Gene model (P.falciparum): PF3D7_0719200; Gene product: NIMA related kinase 4 (NEK4) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1202

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0925500; Gene model (P.falciparum): PF3D7_1122800; Gene product: calcium-dependent protein kinase 6 (CDPK6) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1203

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0933700; Gene model (P.falciparum): PF3D7_1113900; Gene product: mitogen-activated protein kinase 2 (MAPK2; MAP2) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1204

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1013300; Gene model (P.falciparum): PF3D7_1431500; Gene product: mitogen-activated protein kinase 1 (MAPK1; MAP1) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1205

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1306900; Gene model (P.falciparum): PF3D7_1443000; Gene product: serine/threonine protein kinase (SRPK2: CLK2) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1206

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1318000; Gene model (P.falciparum): PF3D7_1454300; Gene product: SNF1-related serine/threonine protein kinase KIN (KIN) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1207

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1352600; Gene model (P.falciparum): PF3D7_1338900; Gene product: serine/threonine protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1208

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1460500; Gene model (P.falciparum): PF3D7_1247500; Gene product: serine/threonine protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1209

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0308500; Gene model (P.falciparum): PF3D7_0211700; Gene product: tyrosine kinase-like protein, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1210

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0314200; Gene model (P.falciparum): PF3D7_0217500; Gene product: calcium-dependent protein kinase 1 (CDPK1; PfCPK) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1211

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0410400; Gene model (P.falciparum): PF3D7_0312400; Gene product: glycogen synthase kinase 3 (GSK3) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1212

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_0829600; Gene model (P.falciparum): PF3D7_0928800; Gene product: serine/threonine protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1213

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1305200; Gene model (P.falciparum): PF3D7_1441300; Gene product: serine/threonine protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1214

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1362100; Gene model (P.falciparum): PF3D7_1349300; Gene product: tyrosine kinase-like protein (TKL3) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1215

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1414500; Gene model (P.falciparum): PF3D7_1316000; Gene product: protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1216

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1421600; Gene model (P.falciparum): PF3D7_0715300; Gene product: calcium/calmodulin-dependent protein kinase, putative Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	No phenotype has been described

RMgm-1217

Malaria parasite	P. berghei
Genotype
Other modification	Gene model (rodent): PBANKA_1445600; Gene model (P.falciparum): PF3D7_1230900; Gene product: serine/threonine protein kinase RIO1, putative (RIO1) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants
Phenotype	Asexual bloodstage;

RMgm-1218

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0314200; Gene model (P.falciparum): PF3D7_0217500; Gene product: calcium-dependent protein kinase 1 (CDPK1; PfCPK)
Phenotype	No phenotype has been described

RMgm-1219

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0410400; Gene model (P.falciparum): PF3D7_0312400; Gene product: glycogen synthase kinase 3 (GSK3)
Phenotype	No phenotype has been described

RMgm-1220

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_0829600; Gene model (P.falciparum): PF3D7_0928800; Gene product: serine/threonine protein kinase, putative
Phenotype	No phenotype has been described

RMgm-1221

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1362100; Gene model (P.falciparum): PF3D7_1349300; Gene product: tyrosine kinase-like protein (TKL3)
Phenotype	No phenotype has been described

RMgm-1222

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1445600; Gene model (P.falciparum): PF3D7_1230900; Gene product: serine/threonine protein kinase RIO1, putative (RIO1)
Phenotype	Asexual bloodstage;

RMgm-1223

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_0625700; Gene model (P.falciparum): Not available; Gene product: 18S ribosomal RNA (small subunit (ssu) of the d-type ribosomal rna gene unit)
Phenotype	Oocyst; Sporozoite;

RMgm-1224

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_0522400; Gene model (P.falciparum): Not available; Gene product: 18S ribosomal RNA (small subunit (ssu) of the c-type ribosomal rna gene unit)
Phenotype	No phenotype has been described

RMgm-1225

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1128100; Gene model (P.falciparum): PF3D7_0629300; Gene product: phosphatidylcholine-sterol acyltransferase, putative \| phospholipase, putative (PL, UIS10)
Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Sporozoite; Liver stage;

RMgm-1226

Malaria parasite	P. berghei
Genotype
Transgene	Transgene Plasmodium: Gene model: PBANKA_1128100; Gene model (P.falciparum): PF3D7_0629300; Gene product: phosphatidylcholine-sterol acyltransferase, putative \| phospholipase, putative (PL, UIS10) Promoter: Gene model: PBANKA_1003000; Gene model (P.falciparum): PF3D7_0405300; Gene product: liver specific protein 2, putative \| sequestrin \| 6-cysteine protein (6-cysteine protein; sequestrin; LISP2) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Liver stage;

RMgm-1227

Malaria parasite	P. berghei
Genotype
Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-1228

Malaria parasite	P. berghei
Genotype
Transgene	Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0800500; Gene model (P.falciparum): PF3D7_1252200; Gene product: chitinase (CHT1) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-1229

Malaria parasite	P. berghei
Genotype
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0800500; Gene model (P.falciparum): PF3D7_1252200; Gene product: chitinase (CHT1) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	No phenotype has been described

RMgm-1230

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1103300; Gene model (P.falciparum): PF3D7_0503600; Gene product: myosin B (MyoB; PfM-B) Name tag: GFP
Phenotype	Asexual bloodstage; Fertilization and ookinete; Sporozoite; Liver stage;

RMgm-1231

Malaria parasite	P. yoelii
Genotype
Disrupted	Gene model (rodent): PY17X_1421600; Gene model (P.falciparum): PF3D7_1321600; Gene product: phosphodiesterase gamma, putative (PDEgamma; PDEγ)
Transgene	Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_1421600; Gene product: phosphodiesterase gamma, putative (PDEgamma)
Phenotype	Asexual bloodstage; Sporozoite; Liver stage;

RMgm-1232

Malaria parasite	P. yoelii
Genotype
Tagged	Gene model (rodent): PY17X_1421600; Gene model (P.falciparum): PF3D7_1321600; Gene product: phosphodiesterase gamma, putative (PDEgamma; PDEγ) Name tag: cMyc (4x)
Phenotype	Asexual bloodstage; Sporozoite;

RMgm-1233

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1200400; Gene model (P.falciparum): Not available; Gene product: BIR protein PIR protein (PIR protein; PIR4) Name tag: mCherry
Phenotype	Asexual bloodstage;

RMgm-1234

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1300200; Gene model (P.falciparum): Not available; Gene product: BIR protein PIR protein (PIR protein; PIR5) Name tag: mCherry
Phenotype	Asexual bloodstage;

RMgm-1235

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1040561; Gene model (P.falciparum): Not available; Gene product: PIR protein; BIR protein (PIR7) Name tag: mCherry
Phenotype	Asexual bloodstage;

RMgm-1236

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0524600; Gene model (P.falciparum): Not available; Gene product: BIR protein; PIR protein (PIR8) Name tag: mCherry
Phenotype	Asexual bloodstage; Liver stage;

RMgm-1237

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1365500; Gene model (P.falciparum): Not available; Gene product: intra-erythrocytic P. berghei-induced structures protein 1 exported protein IBIS1 (Exported protein IBIS1; intra-erythrocytic P. berghei-induced structures protein 1) Name tag: GFP
Phenotype	Asexual bloodstage; Liver stage;

RMgm-1238

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0100600; Gene model (P.falciparum): Not available; Gene product: schizont membrane associated cytoadherence protein (SMAC) Name tag: mCherry
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Liver stage;

RMgm-1239

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1450300; Gene model (P.falciparum): PF3D7_1235700; Gene product: ATP synthase subunit beta, mitochondrial (PbATPβ protein)
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-1240

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1450300; Gene model (P.falciparum): PF3D7_1235700; Gene product: ATP synthase subunit beta, mitochondrial (PbATPβ protein)
Transgene	Transgene not Plasmodium: YFP Promoter: Gene model: PBANKA_0719300; Gene model (P.falciparum): PF3D7_0417200; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (DHFR/TS) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR/TS) Replacement locus: Gene model: PBANKA_1450300; Gene product: ATP synthase subunit beta, mitochondrial (PbATPβ protein)
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-1241

Malaria parasite	P. berghei
Genotype
Disrupted	Gene model (rodent): PBANKA_1450300; Gene model (P.falciparum): PF3D7_1235700; Gene product: ATP synthase subunit beta, mitochondrial (PbATPβ protein)
Transgene	Transgene not Plasmodium: dtTomato Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS) Replacement locus: Gene model: Not available; Gene product: Not available
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

RMgm-1242

Malaria parasite	P. berghei
Genotype
Transgene	Transgene not Plasmodium: GFP (fused to mtichondrial targeting sequence of PbATPβ) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (DHFR/TS)
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Oocyst; Sporozoite;

RMgm-1243

Malaria parasite	P. berghei
Genotype
Transgene	Transgene not Plasmodium: dtTomato Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS) Replacement locus: Gene model: Not available; Gene product: Not available
Phenotype	Asexual bloodstage;

RMgm-1244

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1327300; Gene model (P.falciparum): Not available; Gene product: fam-a protein (fam-a2) Name tag: mCherry
Tagged	Gene model (rodent): PBANKA_0836800; Gene model (P.falciparum): Not available; Gene product: erythrocyte membrane associated protein 1; fam-a protein (EMAP1; fam-a1) Name tag: GFP
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Liver stage;

RMgm-1245

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0836800; Gene model (P.falciparum): Not available; Gene product: erythrocyte membrane associated protein 1; fam-a protein (EMAP1; fam-a1) Name tag: mCherry
Tagged	Gene model (rodent): PBANKA_1327300; Gene model (P.falciparum): Not available; Gene product: fam-a protein (fam-a2) Name tag: EGFP
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Liver stage;

RMgm-1246

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_0316700; Gene model (P.falciparum): Not available; Gene product: fam-b protein (fam-b1) Name tag: mCherry
Tagged	Gene model (rodent): PBANKA_0722600; Gene model (P.falciparum): Not available; Gene product: fam-b protein (fam-b2) Name tag: EGFP
Phenotype	Asexual bloodstage; Gametocyte/Gamete; Liver stage;

RMgm-1247

Malaria parasite	P. berghei
Genotype
Tagged	Gene model (rodent): PBANKA_1400300; Gene model (P.falciparum): Not available; Gene product: PIR protein; BIR protein (PIR1) Name tag: mCherry
Tagged	Gene model (rodent): PBANKA_0500200; Gene model (P.falciparum): Not available; Gene product: BIR protein; PIR protein (PIR3) Name tag: EGFP
Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_0915000; Gene model (P.falciparum): PF3D7_1133400; Gene product: apical membrane antigen 1 (ama-1) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p)
Phenotype	Asexual bloodstage; Liver stage;

all	gene disrupted	gene mutated / conditional mutagenesis	gene tagged	gene transgene all transgene promoter 3'UTR	gene other

all	gene disrupted	gene mutated / conditional mutagenesis	gene tagged	gene other

all	gene disrupted	gene mutated / conditional mutagenesis	gene tagged	gene transgene all transgene promoter 3'UTR	gene other

all	gene disrupted	gene mutated / conditional mutagenesis	gene tagged	gene transgene	gene other

RMgmDB - Rodent Malaria genetically modified Parasites

Search for genetically modified parasite lines by:

4890 results for: