Mutant/mutation
The endogenous hexose transporter 1 gene (pbht1) is replaced with a HA-tagged copy of pbht1.

Protein (function)
PbHT1 is a facilitative hexose transporter in the Major Facilitator Superfamily of integral membrane proteins that mediates the uptake of glucose and fructose by the parasite. HT1 of P. falciparum is known to transport glucose and fructose and is essential for blood stage parasites, in vitro (see also RMgm-390 and 'Additional information' below).

Phenotype
In the paper unsuccessful attempt to disrupt pbht1 are reported (see also RMgm-390). These unsuccessful attempts indicate an essential role of PbHT1 in the asexual blood stages.
Immunofluorescence analysis using rabbit anti-HA antibody showed parasite surface location in parasite blood stages (schizonts) and on the plasma membrane of liver stages. Normal production of  blood stages, sporozoites and liver stages indicates that the HA-tag does not affect the function of PbHT1.
See also the analyses of mutant RMgm-391, which expresses a (C-terminal) GFP-tagged form of PbHT1.

Additional information
In the paper it is shown that PbHT1 can transport glucose (Km~87 µM), mannose (Ki~93 µM), fructose (Ki~0.54 mM), and galactose (Ki~5 mM).
In the paper a mutant (RMgm-604) is described in which the endogenous hexose transporter 1 gene (pbht1) is replaced with the P. falciparum ortholog, pfht1

Other mutants
RMgm-390: unsuccessful attempt to disrupt pbht1
RMgm-391: a mutant expressing a GFP-tagged form of PbHT1
RMgm-604: a mutant in which the endogenous hexose transporter 1 gene (pbht1) is replaced with the P. falciparum ortholog, pfht1