Search database by RMgm ID
RMgm-12
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-1200
Malaria parasite | P. berghei |
Genotype | |
Other modification | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Details modification: Successful gene deletion as determined by barcode PCR in a large pool of gene-deletion mutants |
Phenotype | No phenotype has been described |
RMgm-1510
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (cdpk4) Details mutation: The mutant contains a FRTed ORF of the cdpk4 locus Details conditional mutagenesis: The ORF of cdpk4 is removed in the sporozoite stage by the Flp/FRT system |
Transgene |
Transgene not Plasmodium: FlpL recombinase of yeast (FlpL) Promoter: Gene model: PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2; SSP-2) 3'UTR: Gene model: PBANKA_1349800; Gene product: sporozoite surface protein 2 thrombospondin-related anonymous protein (sporozoite surface protein 2; SSP2; SSP-2) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-2125
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-4155
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4156
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Details mutation: The mutant expresses a mutated form of CDPK4, CDPK4(S147M) |
Phenotype | No phenotype has been described |
RMgm-4157
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Name tag: c-myc |
Phenotype | No phenotype has been described |
RMgm-4158
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Details mutation: myristoylated glycine 2 was replaced by an alanine residue preventing myristoylation of CDPK4 |
Tagged | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Name tag: c-myc |
Phenotype |
Gametocyte/Gamete;
|
RMgm-4546
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) |
Phenotype |
Asexual bloodstage;
|
RMgm-4552
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) |
Mutated | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Details mutation: a mutated pkg in which the threonine gatekeeper residue ((T619Q) is mutated to glutamine |
Tagged | Gene model (rodent): PBANKA_1008200; Gene model (P.falciparum): PF3D7_1436600; Gene product: cGMP-dependent protein kinase (PKG) Name tag: triple-HA |
Phenotype |
Asexual bloodstage;
|
RMgm-4557
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Name tag: triple-HA |
Phenotype |
Asexual bloodstage;
|
RMgm-4818
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_0617900; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) |
Phenotype |
Gametocyte/Gamete;
|
RMgm-4868
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0615200; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (CDPK4) Details mutation: C-terminal tagging of CDPK4 with the AID-2xHA degron |
Transgene |
Transgene not Plasmodium: (myc-tagged) Os-TIR1 protein Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0514900; Gene product: 28 kDa ookinete surface protein (P28) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-5159
Malaria parasite | P. yoelii |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PY17X_0617900; Gene model (P.falciparum): PF3D7_0717500; Gene product: calcium-dependent protein kinase 4 (cdpk4) Promoter: Gene model: PBANKA_1324300; Gene model (P.falciparum): PF3D7_1460600; Gene product: inner membrane complex sub-compartment protein 3 (ISP3) 3'UTR: Gene model: Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|