Search database by RMgm ID
RMgm-4051
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1463600; Gene model (P.falciparum): PF3D7_1250700; Gene product: conserved Plasmodium protein, unknown function |
Phenotype | No phenotype has been described |
RMgm-4052
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1463700; Gene model (P.falciparum): PF3D7_1250800; Gene product: DNA repair protein rhp16, putative |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-4053
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1464600; Gene model (P.falciparum): PF3D7_1251600; Gene product: conserved Plasmodium protein, unknown function |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-4054
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1465500; Gene model (P.falciparum): Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-4055
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1466100; Gene model (P.falciparum): Not available; Gene product: Not available |
Phenotype |
Asexual bloodstage;
|
RMgm-4056
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0512800; Gene model (P.falciparum): PF3D7_1028700; Gene product: merozoite TRAP-like protein (MTRAP) |
Transgene |
Transgene not Plasmodium: mCherrry Promoter: Gene model: Not available; Gene model (P.falciparum): Not available; Gene product: Not available 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_0512800; Gene product: merozoite TRAP-like protein (MTRAP) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-4057
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1030600; Gene model (P.falciparum): PF3D7_1414500; Gene product: atypical protein kinase, ABC-1 family, putative (ABCk2) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p) |
Phenotype | No phenotype has been described |
RMgm-4058
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1137800; Gene model (P.falciparum): PF3D7_1361800; Gene product: glideosome-associated connector (GAC) Name tag: GFP |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-4059
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0902500; Gene model (P.falciparum): PF3D7_1146600; Gene product: oocyst rupture protein 1, putative | CCAAT-box DNA binding protein subunit B (ORP1; NFYB) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS) Replacement locus: Gene model: PBANKA_0902500; Gene product: oocyst rupture protein 1, putative; CCAAT-box DNA binding protein subunit B (ORP1; NFYB) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4060
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1303400; Gene model (P.falciparum): PF3D7_1439500; Gene product: oocyst rupture protein 2, putative (ORP2; NFYC) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1340000; Gene product: dihydrofolate synthase/folylpolyglutamate synthase, putative (PbDHFS-FPGS) Replacement locus: Gene model: PBANKA_1303400; Gene product: oocyst rupture protein 2, putative (ORP2; NFYC) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4061
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0902500; Gene model (P.falciparum): PF3D7_1146600; Gene product: oocyst rupture protein 1, putative | CCAAT-box DNA binding protein subunit B (ORP1; NFYB) Details mutation: Deletion of part of the α2 to αC domains of the Histone Fold Domain (amino 52 acids 797 to 860). |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4062
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: ORP1 (PBANKA_0902500) fused to GFP Promoter: Gene model: PBANKA_0902500; Gene model (P.falciparum): PF3D7_1146600; Gene product: oocyst rupture protein 1, putative | CCAAT-box DNA binding protein subunit B (ORP1; NFYB) 3'UTR: Gene model: PBANKA_0902500; Gene product: oocyst rupture protein 1, putative; CCAAT-box DNA binding protein subunit B (ORP1; NFYB) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit)) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-4063
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1303400; Gene model (P.falciparum): PF3D7_1439500; Gene product: oocyst rupture protein 2, putative (ORP2; NFYC) Name tag: mCherry |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4064
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1009500; Gene model (P.falciparum): PF3D7_1435300; Gene product: NAD(P)H-dependent glutamate synthase, putative (GLuS) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Oocyst;
Sporozoite; Liver stage; |
RMgm-4065
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1119200; Gene model (P.falciparum): PF3D7_0620000; Gene product: secreted ookinete protein 25, putative | ookinete surface-associated protein 8, putative (PSOP25, POS8) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-4066
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1432300; Gene model (P.falciparum): PF3D7_1216600; Gene product: cell traversal protein for ookinetes and sporozoites (CelTOS) Details mutation: The P. berghei celtos gene replaced by P. falciparum celtos |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4067
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1335900; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene Plasmodium: Gene model: PF3D7_1302200; Gene model (P.falciparum): PF3D7_1302200; Gene product: early transcribed membrane protein 13 (ETRAMP13; UIS3) Promoter: Gene model: PBANKA_0501200; Gene model (P.falciparum): Not available; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) 3'UTR: Gene model: PBANKA_0501200; Gene product: early transcribed membrane protein up-regulated in infective sporozoites (ETRAMP10.3; UIS4) Replacement locus: Gene model: PBANKA_1206800; Gene product: zinc finger (CCCH type) protein, putative |
Phenotype |
Sporozoite; |
RMgm-4068
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1003600; Gene model (P.falciparum): PF3D7_0404500; Gene product: 6-cysteine protein (P36p; P52) |
Disrupted | Gene model (rodent): PY17X_1003500; Gene model (P.falciparum): PF3D7_0404400; Gene product: 6-cysteine protein (P36) |
Disrupted | Gene model (rodent): PY17X_0903500; Gene model (P.falciparum): PF3D7_1147000; Gene product: sporozoite and liver stage asparagine-rich protein | sporozoite asparagine-rich protein (SAP1, SLARP; sporozoite (and liver stage) asparagine-rich protein; S22) |
Phenotype |
Liver stage; |
RMgm-4069
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_0415800; Gene model (P.falciparum): PF3D7_0315200; Gene product: circumsporozoite- and TRAP-related protein (CTRP) |
Tagged | Gene model (rodent): PY17X_0515900; Gene model (P.falciparum): PF3D7_1030900; Gene product: ookinete surface protein P28 (P28, Pfs28) Name tag: mCherry |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-4070
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_0410700; Gene model (P.falciparum): PF3D7_0310100; Gene product: calcium-dependent protein kinase 3 (CDPK3) |
Tagged | Gene model (rodent): PY17X_0515900; Gene model (P.falciparum): PF3D7_1030900; Gene product: ookinete surface protein P28 (P28, Pfs28) Name tag: mCherry |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-4071
Malaria parasite | P. yoelii |
Genotype | |
Tagged | Gene model (rodent): PY17X_0515900; Gene model (P.falciparum): PF3D7_1030900; Gene product: ookinete surface protein P28 (P28, Pfs28) Name tag: mCherry |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-4072
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0910900; Gene model (P.falciparum): PF3D7_1137800; Gene product: sporozoite surface protein essential for liver stage development, putative (SPELD) |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0711900; Gene product: heat shock protein 70 (HSP70) Replacement locus: Gene model: PBANKA_0910900; Gene product: sporozoite surface protein essential for liver stage development, putative (SPELD) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-4073
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0910900; Gene model (P.falciparum): PF3D7_1137800; Gene product: sporozoite surface protein essential for liver stage development, putative (SPELD) Name tag: mCherry |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4074
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1026200; Gene model (P.falciparum): PF3D7_1416500; Gene product: NADP-specific glutamate dehydrogenase (GDH1; GDHa) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4075
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1228200; Gene model (P.falciparum): PF3D7_0802000; Gene product: glutamate dehydrogenase, putative (GDH3; GDHc) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4076
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1014000; Gene model (P.falciparum): PF3D7_1430700; Gene product: NADP-specific glutamate dehydrogenase (GDH2; GDHb) |
Phenotype | No phenotype has been described |
RMgm-4077
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1026200; Gene model (P.falciparum): PF3D7_1416500; Gene product: NADP-specific glutamate dehydrogenase (GDH1; GDHa) |
Disrupted | Gene model (rodent): PBANKA_1228200; Gene model (P.falciparum): PF3D7_0802000; Gene product: glutamate dehydrogenase, putative (GDH3; GDHc) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4078
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1003400; Gene model (P.falciparum): PF3D7_0405700; Gene product: lysine decarboxylase, putative (lysine decarboxylase/ glutamate decarboxylase (LDC/GAD)) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-4079
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0107400; Gene model (P.falciparum): PF3D7_0608800; Gene product: ornithine aminotransferase (OAT) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
|
RMgm-4080
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0306700; Gene model (P.falciparum): PF3D7_0209600; Gene product: transporter, putative (TRP) |
Phenotype | No phenotype has been described |
RMgm-4081
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1355200; Gene model (P.falciparum): PF3D7_1342100; Gene product: aconitate hydratase | iron regulatory protein (ACO; IRP) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-4082
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1355900; Gene model (P.falciparum): PF3D7_1342800; Gene product: phosphoenolpyruvate carboxykinase (PEPCK) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4083
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1022600; Gene model (P.falciparum): PF3D7_1420600; Gene product: pantothenate kinase 1, putative (PANK1) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4084
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0611400; Gene model (P.falciparum): PF3D7_1437400; Gene product: pantothenate kinase 2, putative (PANK2) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4085
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1022600; Gene model (P.falciparum): PF3D7_1420600; Gene product: pantothenate kinase 1, putative (PANK1) |
Disrupted | Gene model (rodent): PBANKA_0611400; Gene model (P.falciparum): PF3D7_1437400; Gene product: pantothenate kinase 2, putative (PANK2) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4086
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1319700; Gene model (P.falciparum): PF3D7_1456000; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4087
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0521700; Gene model (P.falciparum): PF3D7_0420300; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4088
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0909600; Gene model (P.falciparum): PF3D7_1139300; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4089
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0939100; Gene model (P.falciparum): PF3D7_1107800; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4090
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1356000; Gene model (P.falciparum): PF3D7_1342900; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4091
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0109500; Gene model (P.falciparum): PF3D7_0611200; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4092
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0835200; Gene model (P.falciparum): PF3D7_0934400; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4093
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1415700; Gene model (P.falciparum): PF3D7_1317200; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4094
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0112100; Gene model (P.falciparum): PF3D7_0613800; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4095
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1205900; Gene model (P.falciparum): PF3D7_1007700; Gene product: AP2 domain transcription factor AP2-I (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4096
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1228100; Gene model (P.falciparum): PF3D7_0802100; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4097
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1453700; Gene model (P.falciparum): PF3D7_1239200; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4098
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1313200; Gene model (P.falciparum): PF3D7_1449500; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4099
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1403700; Gene model (P.falciparum): PF3D7_1305200; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4100
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0932300; Gene model (P.falciparum): PF3D7_1115500; Gene product: AP2 domain transcription factor, putative (ApiAP2) |
Phenotype | No phenotype has been described |
RMgm-4101
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1437500; Gene model (P.falciparum): PF3D7_1222600; Gene product: AP2 domain transcription factor AP2-G (ApiAP2; AP2-G) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4102
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1034300; Gene model (P.falciparum): PF3D7_1408200; Gene product: AP2 domain transcription factor AP2-G2, putative (ApiAP2; AP2-G2) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
Oocyst;
|
RMgm-4103
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1015500; Gene model (P.falciparum): PF3D7_1429200; Gene product: AP2 domain transcription factor AP2-O3, putative (ApiAP2; AP2-O3; PbAP2-FG2) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-4104
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0905900; Gene model (P.falciparum): PF3D7_1143100; Gene product: AP2 domain transcription factor AP2-O, putative (ApiAP2; AP2-O) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Fertilization and ookinete;
Oocyst;
|
RMgm-4105
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1231600; Gene model (P.falciparum): PF3D7_0516800; Gene product: AP2 domain transcription factor AP2-O2, putative (ApiAP2; AP2-O2) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-4106
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1363700; Gene model (P.falciparum): PF3D7_1350900; Gene product: AP2 domain transcription factor AP2-O4, putative (ApiAP2; AP2-O4) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4107
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1034300; Gene model (P.falciparum): PF3D7_1408200; Gene product: AP2 domain transcription factor AP2-G2, putative (ApiAP2; AP2-G2) |
Disrupted | Gene model (rodent): PBANKA_1437500; Gene model (P.falciparum): PF3D7_1222600; Gene product: AP2 domain transcription factor AP2-G (ApiAP2; AP2-G) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4108
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1329800; Gene model (P.falciparum): PF3D7_1466400; Gene product: AP2 domain transcription factor AP2-SP (ApiAP2; AP2-SP) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4109
Malaria parasite | P. yoelii |
Genotype | |
Disrupted | Gene model (rodent): PY17X_1126500; Gene model (P.falciparum): PF3D7_0626300; Gene product: 3-oxoacyl-acyl-carrier protein synthase I/II (FABB/F) |
Transgene |
Transgene not Plasmodium: GFP-Luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: PY17X_0306600; Gene product: 6-cysteine protein (P230p; 230p) |
Phenotype |
Liver stage; |
RMgm-4110
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. berghei csp gene replaced by P. falciparum csp |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4111
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1432300; Gene model (P.falciparum): PF3D7_1216600; Gene product: cell traversal protein for ookinetes and sporozoites (CelTOS) Details mutation: The P. berghei celtos gene replaced by P. vivax (Sal I) celtos (PVX_123510) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4112
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1349800; Gene model (P.falciparum): PF3D7_1335900; Gene product: thrombospondin-related anonymous protein | sporozoite surface protein 2 (TRAP; SSP2) Details mutation: The P. berghei trap gene replaced by P. falciparum trap |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4113
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1001800; Gene model (P.falciparum): PF3D7_0404100; Gene product: AP2 domain transcription factor AP2-SP2, putative (ApiAP2; AP2-SP2) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4114
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1121800; Gene model (P.falciparum): PF3D7_0622900; Gene product: AP2 domain transcription factor AP2Tel | AP2 domain transcription factor AP2-SP3, putative (ApiAP2; AP2-SP3) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4115
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0214400; Gene model (P.falciparum): PF3D7_0730300; Gene product: AP2 domain transcription factor AP2-L, putative (ApiAP2; AP2-L) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-4116
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1404100; Gene model (P.falciparum): PF3D7_1305600; Gene product: site-2 protease S2P, putative (S2P) Name tag: triple-HA |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Fertilization and ookinete;
Oocyst;
Sporozoite; |
RMgm-4117
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0707900; Gene model (P.falciparum): PF3D7_0822700; Gene product: thrombospondin-related protein 1, putative (TRP1) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4118
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0707900; Gene model (P.falciparum): PF3D7_0822700; Gene product: thrombospondin-related protein 1, putative (TRP1) |
Transgene |
Transgene not Plasmodium: mCherry Promoter: Gene model: PBANKA_0707900; Gene model (P.falciparum): PF3D7_0822700; Gene product: thrombospondin-related protein 1, putative (TRP1) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_0707900; Gene product: thrombospondin-related protein 1, putative (TRP1) |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4119
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0707900; Gene model (P.falciparum): PF3D7_0822700; Gene product: thrombospondin-related protein 1, putative (TRP1) Name tag: GFP |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4120
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0707900; Gene model (P.falciparum): PF3D7_0822700; Gene product: thrombospondin-related protein 1, putative (TRP1) Details mutation: The N-terminal sequence after the signal peptide until the start of the TSR domain (549 aa) removed. |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4121
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0707900; Gene model (P.falciparum): PF3D7_0822700; Gene product: thrombospondin-related protein 1, putative (TRP1) Details mutation: The last 41 amino acids of the open reading frame, corresponding to the CTD removed. |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4122
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_0707900; Gene model (P.falciparum): PF3D7_0822700; Gene product: thrombospondin-related protein 1, putative (TRP1) Name tag: GFP |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4123
Malaria parasite | P. chabaudi |
Genotype | |
Transgene |
Transgene not Plasmodium: Firefly luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: PCHAS_0308200; Gene product: 6-cysteine protein (P230p) |
Phenotype |
Asexual bloodstage;
|
RMgm-4124
Malaria parasite | P. chabaudi |
Genotype | |
Transgene |
Transgene not Plasmodium: Firefly luciferase Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Insertion locus: Gene model: PCHAS_0308200; Gene product: 6-cysteine protein (P230p) |
Phenotype |
Asexual bloodstage;
|
RMgm-4125
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_0926700; Gene model (P.falciparum): PF3D7_1121600; Gene product: exported protein 1 | circumsporozoite-related antigen | parasitophorous vacuole membrane antigen QF 116 (EXP1; CRA; Ag5.1; HEP17) |
Phenotype | No phenotype has been described |
RMgm-4126
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Mutated | Gene model (rodent): PBANKA_0926700; Gene model (P.falciparum): PF3D7_1121600; Gene product: exported protein 1 | circumsporozoite-related antigen | parasitophorous vacuole membrane antigen QF 116 (EXP1; CRA; Ag5.1; HEP17) Details mutation: Replacement of the promoter region by the ama1-PBANKA_091500-promoter by 'promoter swap' technology |
Phenotype | No phenotype has been described |
RMgm-4127
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0926700; Gene model (P.falciparum): PF3D7_1121600; Gene product: exported protein 1 | circumsporozoite-related antigen | parasitophorous vacuole membrane antigen QF 116 (EXP1; CRA; Ag5.1; HEP17) Details mutation: The C2 terminal region (93 bp) of the exp1 gene deleted |
Transgene |
Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Liver stage; |
RMgm-4128
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1329100; Gene model (P.falciparum): PF3D7_1465700; Gene product: plasmepsin VIII, putative |
Transgene |
Transgene not Plasmodium: GFP Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PBANKA_1329100; Gene product: plasmepsin VIII |
Phenotype |
Oocyst;
Sporozoite; Liver stage; |
RMgm-4129
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1202000; Gene model (P.falciparum): PF3D7_1003600; Gene product: inner membrane complex protein 1c, putative (IMC1c; ALV2) Details mutation: Three carboxy-terminal cysteines substituted and tagged with mCherry |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4130
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0208300; Gene model (P.falciparum): PF3D7_0104800; Gene product: novel putative transporter 1, putative (Novel Putative Transporter, NPT1) |
Phenotype |
Gametocyte/Gamete;
|
RMgm-4131
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1032100; Gene model (P.falciparum): PF3D7_1410400; Gene product: rhoptry-associated protein 1 (RAP1) Name tag: triple-HA |
Phenotype |
Asexual bloodstage;
|
RMgm-4132
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1032100; Gene model (P.falciparum): PF3D7_1410400; Gene product: rhoptry-associated protein 1 (RAP1) Details mutation: The rap1 promoter modified to contain a tet-inducible promoter and TRAD4 activating domain Details conditional mutagenesis: Downregulation of RAP expression by addition of the tetracycline derivative anhydrotetracycline(ATc) |
Phenotype |
Asexual bloodstage;
|
RMgm-4133
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1101400; Gene model (P.falciparum): PF3D7_0501600; Gene product: rhoptry-associated protein 2 (RAP2/3; rhoptry-associated protein 2/3) Details mutation: The rap2/3 promoter modified to contain a tet-inducible promoter and TRAD4 activating domain Details conditional mutagenesis: Downregulation of RAP expression by addition of the tetracycline derivative anhydrotetracycline(ATc) |
Phenotype |
Asexual bloodstage;
|
RMgm-4134
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PbANKA_0830200; Gene model (P.falciparum): PF3D7_0929400; Gene product: high molecular weight rhoptry protein 2 (RhopH2) Details mutation: The rhoph2 promoter modified to contain a tet-inducible promoter and TRAD4 activating domain Details conditional mutagenesis: Downregulation of RhopH2 by addition of the tetracycline derivative anhydrotetracycline(ATc) |
Phenotype |
Asexual bloodstage;
|
RMgm-4135
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. berghei csp gene replaced by P. falciparum csp |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4136
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. berghei cs gene replaced by P. vivax cs VK210 (PVP01_0835600) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4137
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_0403200; Gene model (P.falciparum): PF3D7_0304600; Gene product: circumsporozoite (CS) protein (CSP) Details mutation: The P. berghei cs gene replaced by P. vivax cs VK247 (PVP01_0835600) |
Transgene |
Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: PBANKA_0719300; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase, putative (dhfr/ts) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Sporozoite; Liver stage; |
RMgm-4138
Malaria parasite | P. berghei |
Genotype | |
Mutated | Gene model (rodent): PBANKA_1035200; Gene model (P.falciparum): PF3D7_1407000; Gene product: LCCL domain-containing protein | scavenger receptor-like protein (PbSR; P. berghei Scavenger Receptor-like protein; PSLAP; LAP1; CCP3) Details mutation: The pentaxin (PTX) domain removed |
Phenotype |
Oocyst;
Sporozoite; |
RMgm-4139
Malaria parasite | P. chabaudi |
Genotype | |
Disrupted | Gene model (rodent): PCHAS_0101300; Gene model (P.falciparum): Not available; Gene product: schizont membrane associated cytoadherence protein, putative (SMAC) |
Phenotype |
Asexual bloodstage;
|
RMgm-4140
Malaria parasite | P. chabaudi |
Genotype | |
Disrupted | Gene model (rodent): PCHAS_0101300; Gene model (P.falciparum): Not available; Gene product: schizont membrane associated cytoadherence protein, putative (SMAC) |
Transgene |
Transgene not Plasmodium: Luciferase (firefly) Promoter: Gene model: PBANKA_1133300; Gene model (P.falciparum): PF3D7_1357100; Gene product: elongation factor 1-alpha (eef1a) 3'UTR: Gene model: Not available; Gene product: Not available Replacement locus: Gene model: PCHAS_0101300; Gene product: schizont membrane associated cytoadherence protein, putative (SMAC) |
Phenotype |
Asexual bloodstage;
|
RMgm-4141
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: FRB::mCherry::TM Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4142
Malaria parasite | P. berghei |
Genotype | |
Transgene |
Transgene not Plasmodium: FRB::mCherry::TM Promoter: Gene model: PBANKA_0711900; Gene model (P.falciparum): PF3D7_0818900; Gene product: heat shock protein 70 (HSP70) 3'UTR: Gene model: PBANKA_0514900; Gene product: 28 kDa ookinete surface protein (Pbs21; P28) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4143
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0720200; Gene model (P.falciparum): PF3D7_0418100; Gene product: protein SOC1, putative (SOC1) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4144
Malaria parasite | P. berghei |
Genotype | |
Genetic modification not successful | |
Disrupted | Gene model (rodent): PBANKA_1115300; Gene model (P.falciparum): PF3D7_0515700; Gene product: glideosome-associated protein 40, putative (GAP40) |
Phenotype | No phenotype has been described |
RMgm-4145
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1442200; Gene model (P.falciparum): PF3D7_1227500; Gene product: protein SOC2, putative (SOC2) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Asexual bloodstage;
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4146
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_1304500; Gene model (P.falciparum): PF3D7_1440600; Gene product: protein SOC3, putative (SOC3) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4147
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0706400; Gene model (P.falciparum): PF3D7_0824200; Gene product: conserved Plasmodium protein, unknown function (SOC4) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4148
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0704700; Gene model (P.falciparum): PF3D7_0825900; Gene product: conserved Plasmodium protein, unknown function (SOC5) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype | No phenotype has been described |
RMgm-4149
Malaria parasite | P. berghei |
Genotype | |
Disrupted | Gene model (rodent): PBANKA_0707700; Gene model (P.falciparum): PF3D7_0822900; Gene product: conserved Plasmodium protein, unknown function (SOC6) |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
Fertilization and ookinete;
|
RMgm-4151
Malaria parasite | P. berghei |
Genotype | |
Tagged | Gene model (rodent): PBANKA_1442200; Gene model (P.falciparum): PF3D7_1227500; Gene product: protein SOC2, putative (SOC2) Name tag: triple-HA |
Transgene |
Transgene not Plasmodium: RFP Promoter: Gene model: PBANKA_1319500; Gene model (P.falciparum): PF3D7_1455800; Gene product: LCCL domain-containing protein (LAP4; LCCL/lectin adhesive-like protein 4; CCp2) 3'UTR: Gene model: PBANKA_1359600; Gene product: transmission blocking target antigen precursor 6-cysteine protein (P48/45) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Transgene |
Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_0416100; Gene model (P.falciparum): PF3D7_0905300; Gene product: dynein heavy chain, putative 3'UTR: Gene model: PBANKA_1010600; Gene product: calmodulin, putative (cam) Replacement locus: Gene model: PBANKA_0306000; Gene product: 6-cysteine protein (230p) |
Phenotype |
Gametocyte/Gamete;
|