374 results for:

1. RMgm-1

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_051490; Gene model (P.falciparum): PF10_0302; Gene product: 28 kDa ookinete surface protein (Pbs21; P28)
   Phenotype	Fertilization and ookinete; Oocyst;

   
   
2. RMgm-2

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_051500; Gene model (P.falciparum): PF10_0303; Gene product: 25 kDa ookinete surface antigen precursor (pfs25) (Pbs25; P25)
   Phenotype	Fertilization and ookinete; Oocyst;

   
   
3. RMgm-3

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_051490; Gene model (P.falciparum): PF10_0302; Gene product: 28 kDa ookinete surface protein (Pbs21; P28)
   Disrupted	Gene model (rodent): PBANKA_051500; Gene model (P.falciparum): PF10_0303; Gene product: 25 kDa ookinete surface antigen precursor (pfs25) (Pbs25; P25)
   Phenotype	Fertilization and ookinete; Oocyst;

   
   
4. RMgm-4

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_052270; Gene model (P.falciparum): PFD1050w; Gene product: alpha-tubulin ii
   Phenotype	No phenotype has been described

   
   
5. RMgm-5

   Malaria parasite	P. berghei
   Genotype
   Transgene	Transgene not Plasmodium: GFP (gfp-mut3) Promoter: Gene model: PBANKA_113330; Gene model (P.falciparum): PF13_0305; Gene product: elongation factor 1 alpha (eef1a) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-type unit))
   Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

   
   
6. RMgm-7

   Malaria parasite	P. berghei
   Genotype
   Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_113330; Gene model (P.falciparum): PF13_0305; Gene product: elongation factor 1 alpha (eef1a) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Replacement locus: Gene model: PBANKA_030600; Gene product: Pfs45-48 related protein, putative (230p)
   Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

   
   
7. RMgm-8

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_041770; Gene model (P.falciparum): PFI0180w; Gene product: alpha-tubulin
   Phenotype	No phenotype has been described

   
   
8. RMgm-9

   Malaria parasite	P. berghei
   Genotype
   Disrupted	Gene model (rodent): PBANKA_040320; Gene model (P.falciparum): PFC0210c; Gene product: circumsporozoite (CS) protein (CSP)
   Phenotype	Oocyst; Sporozoite; Liver stage;

   
   
9. RMgm-10

   Malaria parasite	P. berghei
   Genotype
   Genetic modification not successful
   Disrupted	Gene model (rodent): PBANKA_091500; Gene model (P.falciparum): PF11_0344; Gene product: apical membrane antigen 1, AMA1
   Phenotype	No phenotype has been described

   
   
10. RMgm-11

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene Plasmodium: Gene model: PF11_0344; Gene model (P.falciparum): PF11_0344; Gene product: apical membrane antigen 1, AMA1 Promoter: Gene model: PBANKA_091500; Gene model (P.falciparum): PF11_0344; Gene product: apical membrane antigen 1 precursor, putative (AMA1; pb66) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts)
    Phenotype	Asexual bloodstage;

    
    
11. RMgm-12

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_061520; Gene model (P.falciparum): PF07_0072; Gene product: calcium-dependent protein kinase 4 (CDPK4)
    Phenotype	Gametocyte/Gamete; Fertilization and ookinete; Oocyst;

    
    
12. RMgm-13

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: GFP-aequorin (Ca2+ sensor protein). Promoter: Gene model: PBANKA_113330; Gene model (P.falciparum): PF13_0305; Gene product: elongation factor 1 alpha (eef1a) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c-or d-type unit))
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

    
    
13. RMgm-15

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_135960; Gene model (P.falciparum): PF13_0247; Gene product: transmission blocking target antigen precursor (P48/45)
    Phenotype	Gametocyte/Gamete; Fertilization and ookinete;

    
    
14. RMgm-16

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_052480; Gene model (P.falciparum): Not available; Gene product: hypothetical protein (SEP1; early transcribed membrane protein, ETRAMP; Pbsep1)
    Phenotype	No phenotype has been described

    
    
15. RMgm-18

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_052480; Gene model (P.falciparum): Not available; Gene product: hypothetical protein (SEP1; early transcribed membrane protein, ETRAMP; Pbsep1)
    Phenotype	No phenotype has been described

    
    
16. RMgm-21

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): Not available; Gene model (P.falciparum): Not available; Gene product: c-type ribosomal RNA gene unit (c-rRNA gene)
    Phenotype	Oocyst;

    
    
17. RMgm-22

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): Not available; Gene model (P.falciparum): Not available; Gene product: c-type ribosomal RNA gene unit (c-rRNA gene)
    Phenotype	Oocyst;

    
    
18. RMgm-23

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): Not available; Gene model (P.falciparum): Not available; Gene product: d-type ribosomal RNA gene unit (d-rRNA gene)
    Phenotype	Oocyst; Sporozoite;

    
    
19. RMgm-24

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): Not available; Gene model (P.falciparum): Not available; Gene product: d-type ribosomal RNA gene unit (d-rRNA gene)
    Phenotype	Oocyst; Sporozoite;

    
    
20. RMgm-25

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): Not available; Gene model (P.falciparum): Not available; Gene product: d-type ribosomal RNA gene unit (d-rRNA gene)
    Phenotype	Oocyst; Sporozoite;

    
    
21. RMgm-26

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_144400; Gene model (P.falciparum): PFL1420w; Gene product: macrophage migration inhibitory factor homolog, putative (MIF)
    Phenotype	Asexual bloodstage;

    
    
22. RMgm-27

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_144400; Gene model (P.falciparum): PFL1420w; Gene product: macrophage migration inhibitory factor homolog, putative (MIF) Name tag: EGFP
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Fertilization and ookinete; Oocyst; Sporozoite;

    
    
23. RMgm-28

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-65) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_113330; Gene model (P.falciparum): PF13_0305; Gene product: elongation factor 1 alpha (eef1a) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (d-type unit))
    Phenotype	Asexual bloodstage; Gametocyte/Gamete;

    
    
24. RMgm-29

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_113330; Gene model (P.falciparum): PF13_0305; Gene product: elongation factor 1 alpha (eef1a) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Replacement locus: Gene model: PBANKA_030600; Gene product: Pfs45-48 related protein, putative (230p)
    Phenotype	Asexual bloodstage; Gametocyte/Gamete; Oocyst; Sporozoite; Liver stage;

    
    
25. RMgm-30

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_091500; Gene model (P.falciparum): PF11_0344; Gene product: apical membrane antigen 1, AMA1 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (d-type unit))
    Phenotype	Asexual bloodstage;

    
    
26. RMgm-31

    Malaria parasite	P. berghei
    Genotype
    Tagged	Gene model (rodent): PBANKA_144400; Gene model (P.falciparum): PFL1420w; Gene product: macrophage migration inhibitory factor homolog, putative (MIF) Name tag: c-myc
    Phenotype	Asexual bloodstage; Gametocyte/Gamete;

    
    
27. RMgm-32

    Malaria parasite	P. berghei
    Genotype
    Transgene	Transgene not Plasmodium: A fusion of GFP (gfp-mu3) and Luciferase Firefly (LucIAV) Promoter: Gene model: PBANKA_091500; Gene model (P.falciparum): PF11_0344; Gene product: apical membrane antigen 1, AMA1 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Replacement locus: Gene model: PBANKA_030600; Gene product: Pfs45-48 related protein, putative (230p)
    Phenotype	Asexual bloodstage;

    
    
28. RMgm-33

    Malaria parasite	P. chabaudi
    Genotype
    Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_113330; Gene model (P.falciparum): PF13_0305; Gene product: elongation factor 1 alpha (eef1a) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (ssu-rrna locus (contig 827))
    Phenotype	Asexual bloodstage;

    
    
29. RMgm-34

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_020910; Gene model (P.falciparum): PFA0200w; Gene product: Sporozoite stage TSP1 domain protein, S21 (thrombospondin related sporozoite protein; TRSP)
    Phenotype	Sporozoite; Liver stage;

    
    
30. RMgm-35

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_050120; Gene model (P.falciparum): Not available; Gene product: hypothetical protein (UIS4, up-regulated in infective sporozoites)
    Phenotype	Liver stage;

    
    
31. RMgm-36

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_140080; Gene model (P.falciparum): PF13_0012; Gene product: early transcribed membrane protein 13, ETRAMP13 (UIS3; up-regulated in infective sporozoites)
    Phenotype	Liver stage;

    
    
32. RMgm-37

    Malaria parasite	P. yoelii
    Genotype
    Disrupted	Gene model (rodent): PY03011; Gene model (P.falciparum): PF13_0012; Gene product: early transcribed membrane protein 13, ETRAMP13 (UIS3, up-regulated in infective sporozoites)
    Phenotype	Liver stage;

    
    
33. RMgm-38

    Malaria parasite	P. yoelii
    Genotype
    Disrupted	Gene model (rodent): PY00204; Gene model (P.falciparum): Not available; Gene product: hypothetical protein (UIS4, up-regulated in infective sporozoites)
    Phenotype	Liver stage;

    
    
34. RMgm-39

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_140080; Gene model (P.falciparum): PF13_0012; Gene product: early transcribed membrane protein 13, ETRAMP13 (UIS3, up-regulated in infective sporozoites)
    Disrupted	Gene model (rodent): PBANKA_050120; Gene model (P.falciparum): Not available; Gene product: hypothetical protein (UIS4, up-regulated in infective sporozoites)
    Phenotype	Liver stage;

    
    
35. RMgm-40

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_100220; Gene model (P.falciparum): PFD0215c; Gene product: pf52 protein (P36p; Pb36p; P52)
    Phenotype	Liver stage;

    
    
36. RMgm-41

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_100220; Gene model (P.falciparum): PFD0215c; Gene product: pf52 protein (P36p; Pb36p; P52)
    Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_113330; Gene model (P.falciparum): PF13_0305; Gene product: elongation factor 1 alpha (eef1a) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Insertion locus: Gene model: Not available; Gene product: Not available (small subunit ribosomal rna gene (c/d-type unit))
    Phenotype	Liver stage;

    
    
37. RMgm-42

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_100220; Gene model (P.falciparum): PFD0215c; Gene product: pf52 protein (P36p; Pb36p; P52)
    Disrupted	Gene model (rodent): PBANKA_100210; Gene model (P.falciparum): PFD0210c; Gene product: pbs36 homologue (P36)
    Transgene	Transgene not Plasmodium: GFP (gfp-mu3) Promoter: Gene model: PBANKA_113330; Gene model (P.falciparum): PF13_0305; Gene product: elongation factor 1 alpha (eef1a) 3'UTR: Gene model: PBANKA_071930; Gene product: bifunctional dihydrofolate reductase-thymidylate synthase (dhfr/ts) Replacement locus: Gene model: PBANKA_030600; Gene product: Pfs45-48 related protein, putative (230p)
    Phenotype	Liver stage;

    
    
38. RMgm-43

    Malaria parasite	P. yoelii
    Genotype
    Disrupted	Gene model (rodent): PY01340; Gene model (P.falciparum): PFD0215c; Gene product: pf52 protein (P36p; Pb36p; P52)
    Disrupted	Gene model (rodent): PY01341; Gene model (P.falciparum): PFD0210c; Gene product: pbs36 homologue (P36)
    Phenotype	Liver stage;

    
    
39. RMgm-44

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_100220; Gene model (P.falciparum): PFD0215c; Gene product: pf52 protein (P36p; Pb36p; P52)
    Phenotype	Liver stage;

    
    
40. RMgm-45

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_100210; Gene model (P.falciparum): PFD0210c; Gene product: pbs36 homologue (P36)
    Phenotype	Liver stage;

    
    
41. RMgm-46

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_143230; Gene model (P.falciparum): PFL0800c; Gene product: conserved Plasmodium protein, unknown function (CelTOS; cell traversal protein for ookinetes and sporozoites)
    Phenotype	Fertilization and ookinete; Oocyst; Sporozoite; Liver stage;

    
    
42. RMgm-47

    Malaria parasite	P. berghei
    Genotype
    Disrupted	Gene model (rodent): PBANKA_134980; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2)
    Phenotype	Sporozoite; Liver stage;

    
    
43. RMgm-48

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_134980; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2) Details mutation: Mutation of the A-domain
    Phenotype	Sporozoite; Liver stage;

    
    
44. RMgm-49

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_134980; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2) Details mutation: Mutation of the A-domain
    Phenotype	Sporozoite; Liver stage;

    
    
45. RMgm-50

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_134980; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2) Details mutation: Mutation of the TSR-domain (the distal tryptophan in the WSXW sequence was substituted by alanine)
    Phenotype	Sporozoite; Liver stage;

    
    
46. RMgm-51

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_134980; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2) Details mutation: Mutation of the TSR-domain (basic residues in the C-terminal cluster changed to alanine residues).
    Phenotype	Sporozoite; Liver stage;

    
    
47. RMgm-52

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_134980; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2) Details mutation: Mutations in both the A- and TSR-domain
    Phenotype	Sporozoite; Liver stage;

    
    
48. RMgm-53

    Malaria parasite	P. yoelii
    Genotype
    Disrupted	Gene model (rodent): PY03052; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2)
    Phenotype	Sporozoite; Liver stage;

    
    
49. RMgm-54

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_134980; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2) Details mutation: Mutation in the cytoplasmic tail (abrogation of the tyrosine motif)
    Phenotype	Sporozoite; Liver stage;

    
    
50. RMgm-55

    Malaria parasite	P. berghei
    Genotype
    Mutated	Gene model (rodent): PBANKA_134980; Gene model (P.falciparum): PF13_0201; Gene product: Thrombospondin-related anonymous protein, TRAP (sporozoite surface protein 2; SSP2; SSP-2) Details mutation: Mutation in the cytoplasmic tail (lacking the 14 carboxy-terminal residues)
    Phenotype	Sporozoite; Liver stage;