RMgmDB - Rodent Malaria genetically modified Parasites

  
Search for genetically modified parasite lines by:
Gene ID

Gene Model: P. falciparum or rodent parasite

       
 
 
 
 
  
Text term

For example ama1, ookinete, gamete, GFP
Phenotype

First select the phenotype:

Then select the type of modification:

         
RMgm number

Search database by RMgm number
RMgmDB News
  • 26 March 2010 - In GeneDB there are direct links from appropriate gene pages to genetically modified rodent malaria parasites in the RMgm database.
  • 5 March 2010 - We have now changed from using the previous P. berghei gene models (i.e. PBXXXXX.XX.X) to the new systematic id’s as provided by GeneDB; i.e. PBANKA_xxxxxx). This means:
    - For all mutants only the new gene models will be visible
    - The database can still be searched using old gene models, however only new gene models will be displayed
    - The P. berghei gene models are now linked to GeneDB gene pages (and not to     PlasmoDB, as it still uses the old gene models).
    - Existing links in PlasmoDB out to the RMgm database are not affected. Information on new mutant entries will be linked to PlasmoDB once they have adopted the new gene models.
  • 29 December 2009 - The database contains at this moment information on more than 300 different mutants.
  • 23 July 2009 - In PlasmoDB there are direct links from appropriate gene pages to genetically modified rodent malaria parasites in the RMgm database.
  • 16 June 2009 - The database contains at this moment information on more than 260 different mutants.
  • 1 April 2009 - The database contains at this moment information on more than 200 different mutants.
  • 28 January 2009 - The database contains information on approximately 150 different mutants.
  • 6 November 2008 - This database is in its preliminary stages; we are still technically improving the database. At this moment we have information on less then 100 parasite mutant lines.
  • 5 October 2008 - The new database, RMgmDB, online!

 

 

 

Pberghei.eu hosts a database containing information on genetically modified, mutant malaria parasite generated by many labs worldwide. It contains data of three rodent malaria parasite species; Plasmodium berghei, P. yoelii and P. chabaudi. The aim of this database is to provide the research community access to detailed information on the generation (e.g. disruption, tagging, mutation, transgene expression) and phenotype of mutant malaria parasites.

The database not only provides information on ‘successful’ mutants with a clear phenotype, but also (un)published mutants without a clear phenotype and (un)published negative trials to disrupt genes.


Submission of information or mutants for publication in the database
For all mutants a ‘comment-box’ is available, where it is possible to submit additional information, corrections and comments as well as suggestions for improving the description of the mutants. Information on new mutants to be published in the database can be submitted either in excel format or uploaded directly onto the database (please contact Dr. Chris J. Janse for more information on how to submit/upload this information).


RMgmDB is provided and generated by the Leiden Malaria Research Group (LUMC, Leiden, The Netherlands). For questions, suggestions and remarks please contact Dr. Chris J. Janse

  

 The database is supported by:
BioMalPar

LUMC logo

the European Commission (FP6 BioMalPar Network of Excellence)

the Leiden University Medical Centre
Conceptual design of the database: Dr. C.J. Janse (Leiden Malaria Research Group, Leiden, The Netherlands).
Technical design and realization: StudioDrie StudioDrie; S. Mededovic and A. van Wigcheren